Three-Dimensional Cell Culture: A Breakthrough in Vivo

Dynamic transcription factor activity profiling in 2D and 3D cell cultures

(2012) Abigail D. Bellis et al.   BIOTECHNOLOGY AND BIOENGINEERING

Cancer cell spheroids as a model to evaluate chemotherapy protocols

(2012) Federico Perche et al.   CANCER BIOLOGY & THERAPY

The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer

(2012) Kenny Chitcholtan et al.   Journal of Translational Medicine

Recapitulation of Tumor Heterogeneity and Molecular Signatures in a 3D Brain Cancer Model with Decreased Sensitivity to Histone Deacetylase Inhibition

(2012) Stuart J. Smith et al.   PLoS One

384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids

(2011) Amy Y. Hsiao et al.   BIOTECHNOLOGY AND BIOENGINEERING

Turning round: multipotent stromal cells, a three-dimensional revolution?

(2011) Fatima A. Saleh et al.   CYTOTHERAPY

High drug attrition rates—where are we going wrong?

(2011) Lisa Hutchinson et al.   Nature Reviews Clinical Oncology

Anticancer drug development: the grand challenges

(2010) William N. Hait   NATURE REVIEWS DRUG DISCOVERY

The Use of Animal Models for Cancer Chemoprevention Drug Development

(2010) Vernon E. Steele et al.   SEMINARS IN ONCOLOGY

Models for prevention and treatment of cancer: Problems vs promises

(2009) Bharat B. Aggarwal et al.   BIOCHEMICAL PHARMACOLOGY

Recent advances in three-dimensional multicellular spheroid culture for biomedical research

(2008) Ruei-Zhen Lin et al.   Biotechnology Journal

Three-Dimensional Cell Culture Matrices: State of the Art

(2008) Jungwoo Lee et al.   TISSUE ENGINEERING PART B-REVIEWS

Development of a bioreactor for evaluating novel nerve conduits

(2007) Tao Sun et al.   BIOTECHNOLOGY AND BIOENGINEERING