The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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Title
The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
Authors
Keywords
Miz1, inflammation, hepatocyte NF-κB, metadherin, MTDH, hepatocellular carcinoma, HCC, scRNA-seq
Journal
IMMUNITY
Volume 54, Issue 6, Pages 1168-1185.e8
Publisher
Elsevier BV
Online
2021-05-25
DOI
10.1016/j.immuni.2021.04.027
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Note: Only part of the references are listed.- A comparison of single-cell trajectory inference methods
- (2019) Wouter Saelens et al. NATURE BIOTECHNOLOGY
- Integrated multiomic analysis reveals comprehensive tumour heterogeneity and novel immunophenotypic classification in hepatocellular carcinomas
- (2019) Qi Zhang et al. GUT
- The Role of Myeloid-Derived Cells in the Progression of Liver Disease
- (2019) Chris John Weston et al. Frontiers in Immunology
- Tumor Cell Biodiversity Drives Microenvironmental Reprogramming in Liver Cancer
- (2019) Lichun Ma et al. CANCER CELL
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- (2018) Elham Azizi et al. CELL
- A novel TGF-β and H19 signaling axis in tumor-initiating hepatocytes that regulates hepatic carcinogenesis
- (2018) Jinqiang Zhang et al. HEPATOLOGY
- Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2
- (2018) Tian Lan et al. HEPATOLOGY
- The immunology of hepatocellular carcinoma
- (2018) Marc Ringelhan et al. NATURE IMMUNOLOGY
- Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research
- (2018) Zachary J. Brown et al. Nature Reviews Gastroenterology & Hepatology
- Astrocyte elevated gene-1 (AEG-1) regulates macrophage activation in hepatocellular carcinogenesis
- (2018) Chadia L Robertson et al. CANCER RESEARCH
- Lineage tracking reveals dynamic relationships of T cells in colorectal cancer
- (2018) Lei Zhang et al. NATURE
- Targeting hepatic macrophages to treat liver diseases
- (2017) Frank Tacke JOURNAL OF HEPATOLOGY
- New insights into the multidimensional concept of macrophage ontogeny, activation and function
- (2016) Florent Ginhoux et al. NATURE IMMUNOLOGY
- AEG-1 promotes mesenchymal transition through the activation of Rho GTPases in human glioblastoma cells
- (2016) Sang-Yoon Park et al. ONCOLOGY REPORTS
- STK4 regulates TLR pathways and protects against chronic inflammation–related hepatocellular carcinoma
- (2015) Weiyun Li et al. JOURNAL OF CLINICAL INVESTIGATION
- Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate
- (2015) Ramesh K. Krishnan et al. Nature Communications
- PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis
- (2015) Wenjie Zhang et al. Oncotarget
- Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase
- (2014) S. Peter et al. EMBO Molecular Medicine
- Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles
- (2014) Susanne Walz et al. NATURE
- The expression of Survivin and NF-κB associated with prognostically worse clinicopathologic variables in hepatocellular carcinoma
- (2014) Yi Jin et al. TUMOR BIOLOGY
- Identification of Liver Cancer Progenitors Whose Malignant Progression Depends on Autocrine IL-6 Signaling
- (2013) Guobin He et al. CELL
- Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15
- (2013) S. Inoue et al. GENES & DEVELOPMENT
- A murine model for non-alcoholic steatohepatitis showing evidence of association between diabetes and hepatocellular carcinoma
- (2013) Masato Fujii et al. Medical Molecular Morphology
- Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ
- (2013) Hanh Chi Do-Umehara et al. NATURE IMMUNOLOGY
- NAFLD, NASH and liver cancer
- (2013) Gregory A. Michelotti et al. Nature Reviews Gastroenterology & Hepatology
- Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4
- (2012) Dianne H. Dapito et al. CANCER CELL
- Astrocyte elevated gene-1 promotes hepatocarcinogenesis: Novel insights from a mouse model
- (2012) Jyoti Srivastava et al. HEPATOLOGY
- Miz1 Is a Critical Repressor of cdkn1a during Skin Tumorigenesis
- (2012) Jan Hönnemann et al. PLoS One
- IL-7R-dependent survival and differentiation of early T-lineage progenitors is regulated by the BTB/POZ domain transcription factor Miz-1
- (2011) I. Saba et al. BLOOD
- Oncogene AEG-1 Promotes Glioma-Induced Neurodegeneration by Increasing Glutamate Excitotoxicity
- (2011) S.-G. Lee et al. CANCER RESEARCH
- Metadherin Promotes Hepatocellular Carcinoma Metastasis through Induction of Epithelial-Mesenchymal Transition
- (2011) K. Zhu et al. CLINICAL CANCER RESEARCH
- Obesity, inflammation, and liver cancer
- (2011) Beicheng Sun et al. JOURNAL OF HEPATOLOGY
- Inflammation meets cancer, with NF-κB as the matchmaker
- (2011) Yinon Ben-Neriah et al. NATURE IMMUNOLOGY
- Site-specific ubiquitination is required for relieving the transcription factor Miz1-mediated suppression on TNF- -induced JNK activation and inflammation
- (2011) J. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation
- (2010) Guobin He et al. CANCER CELL
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- The interaction between Myc and Miz1 is required to antagonize TGF -dependent autocrine signaling during lymphoma formation and maintenance
- (2010) J. van Riggelen et al. GENES & DEVELOPMENT
- Bcl-6 and NF- B cistromes mediate opposing regulation of the innate immune response
- (2010) G. D. Barish et al. GENES & DEVELOPMENT
- Transcription Factor Miz-1 Is Required to Regulate Interleukin-7 Receptor Signaling at Early Commitment Stages of B Cell Differentiation
- (2010) Christian Kosan et al. IMMUNITY
- E3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNF -induced JNK activation
- (2010) Y. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MTDH Activation by 8q22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer
- (2009) Guohong Hu et al. CANCER CELL
- A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma
- (2009) Johannes Haybaeck et al. CANCER CELL
- Angiotensin II Activates IκB Kinase Phosphorylation of RelA at Ser536 to Promote Myofibroblast Survival and Liver Fibrosis
- (2009) Fiona Oakley et al. GASTROENTEROLOGY
- Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression
- (2009) Byoung Kwon Yoo et al. JOURNAL OF CLINICAL INVESTIGATION
- Gfi-1 represses CDKN2B encoding p15INK4B through interaction with Miz-1
- (2009) S. Basu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma
- (2009) M. Saito et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Miz1 is a signal- and pathway-specific modulator or regulator (SMOR) that suppresses TNF- -induced JNK1 activation
- (2009) J. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NF- B as a Critical Link Between Inflammation and Cancer
- (2009) M. Karin Cold Spring Harbor Perspectives in Biology
- Molecular Basis of Nuclear Factor- B Activation by Astrocyte Elevated Gene-1
- (2008) D. Sarkar et al. CANCER RESEARCH
- Miz1 and HectH9 regulate the stability of the checkpoint protein, TopBP1
- (2008) Steffi Herold et al. EMBO JOURNAL
- EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features
- (2008) Taro Yamashita et al. GASTROENTEROLOGY
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