Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research
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Title
Mouse models of hepatocellular carcinoma: an overview and highlights for immunotherapy research
Authors
Keywords
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Journal
Nature Reviews Gastroenterology & Hepatology
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-06-14
DOI
10.1038/s41575-018-0033-6
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Note: Only part of the references are listed.- Preclinical models of non-alcoholic fatty liver disease
- (2018) Prasanna K. Santhekadur et al. JOURNAL OF HEPATOLOGY
- A simple diet- and chemical-induced murine NASH model with rapid progression of steatohepatitis, fibrosis and liver cancer
- (2018) Takuma Tsuchida et al. JOURNAL OF HEPATOLOGY
- Successful chemoimmunotherapy against hepatocellular cancer in a novel murine model
- (2017) Guangfu Li et al. JOURNAL OF HEPATOLOGY
- Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma
- (2017) Austin G. Duffy et al. JOURNAL OF HEPATOLOGY
- Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial
- (2017) Anthony B El-Khoueiry et al. LANCET
- Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
- (2017) Shabnam Shalapour et al. NATURE
- Regorafenib as second-line therapy in hepatocellular carcinoma
- (2017) Austin G. Duffy et al. Nature Reviews Gastroenterology & Hepatology
- Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention
- (2017) Zobair Younossi et al. Nature Reviews Gastroenterology & Hepatology
- Exclusion of Kaposi Sarcoma From Analysis of Cancer Burden—Reply
- (2017) Christina Fitzmaurice et al. JAMA Oncology
- The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level
- (2017) et al. JAMA Oncology
- Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development
- (2016) Jessica Endig et al. CANCER CELL
- Inhibition of the Wnt/β-catenin signaling pathway improves the anti-tumor effects of sorafenib against hepatocellular carcinoma
- (2016) Hsiao-Hui Lin et al. CANCER LETTERS
- Humanized Mouse Xenograft Models: Narrowing the Tumor–Microenvironment Gap
- (2016) J. Jason Morton et al. CANCER RESEARCH
- Use of non-invasive imaging to monitor response to aflibercept treatment in murine models of colorectal cancer liver metastases
- (2016) Karianne G. Fleten et al. CLINICAL & EXPERIMENTAL METASTASIS
- Rationale for anti-CD137 cancer immunotherapy
- (2016) Amani Makkouk et al. EUROPEAN JOURNAL OF CANCER
- Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients
- (2016) Andreas Teufel et al. GASTROENTEROLOGY
- Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes
- (2016) Zobair M. Younossi et al. HEPATOLOGY
- Programmed cell death-1 blockade enhances response to stereotactic radiation in an orthotopic murine model of hepatocellular carcinoma
- (2016) David Friedman et al. HEPATOLOGY RESEARCH
- A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer
- (2016) Amon Asgharpour et al. JOURNAL OF HEPATOLOGY
- Experimental in vitro and in vivo models for the study of human hepatitis B virus infection
- (2016) Lena Allweiss et al. JOURNAL OF HEPATOLOGY
- NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis
- (2016) Chi Ma et al. NATURE
- Immunotherapy and stereotactic ablative radiotherapy (ISABR): a curative approach?
- (2016) Michael B. Bernstein et al. Nature Reviews Clinical Oncology
- Erratum: Oncolytic viruses: a new class of immunotherapy drugs
- (2016) Howard L. Kaufman et al. NATURE REVIEWS DRUG DISCOVERY
- Adapting Cancer Immunotherapy Models for the Real World
- (2016) Lauryn E. Klevorn et al. TRENDS IN IMMUNOLOGY
- Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease
- (2016) Aditya Ambade et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Hepatocellular carcinoma
- (2016) Josep M. Llovet et al. Nature Reviews Disease Primers
- Identification and Validation of HCC-specific Gene Transcriptional Signature for Tumor Antigen Discovery
- (2016) Annacarmen Petrizzo et al. Scientific Reports
- Time Course of Contrast Enhancement by Micro-CT with Dedicated Contrast Agents in Normal Mice and Mice with Hepatocellular Carcinoma
- (2015) Jan H. Rothe et al. ACADEMIC RADIOLOGY
- A phase I/IIa study of adjuvant immunotherapy with tumour antigen-pulsed dendritic cells in patients with hepatocellular carcinoma
- (2015) Jeong-Hoon Lee et al. BRITISH JOURNAL OF CANCER
- Radiotherapy Combined with Novel STING-Targeting Oligonucleotides Results in Regression of Established Tumors
- (2015) J. R. Baird et al. CANCER RESEARCH
- PD-1 Blockers
- (2015) Jedd D. Wolchok CELL
- Animal Models of Nonalcoholic Steatohepatitis: Eat, Delete, and Inflame
- (2015) Samar H. Ibrahim et al. DIGESTIVE DISEASES AND SCIENCES
- Tumor-induced CD11b+ Gr-1+ myeloid-derived suppressor cells exacerbate immune-mediated hepatitis in mice in a CD40-dependent manner
- (2015) Tamar Kapanadze et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Adjuvant Immunotherapy With Autologous Cytokine-Induced Killer Cells for Hepatocellular Carcinoma
- (2015) Joon Hyeok Lee et al. GASTROENTEROLOGY
- T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice
- (2015) Christina Dargel et al. GASTROENTEROLOGY
- CXCR4 inhibition in tumor microenvironment facilitates anti-programmed death receptor-1 immunotherapy in sorafenib-treated hepatocellular carcinoma in mice
- (2015) Yunching Chen et al. HEPATOLOGY
- Transgenic mouse models generated by hydrodynamic transfection for genetic studies of liver cancer and preclinical testing of anti-cancer therapy
- (2015) Hye-Lim Ju et al. INTERNATIONAL JOURNAL OF CANCER
- Serum-based tracking of de novo initiated liver cancer progression reveals early immunoregulation and response to therapy
- (2015) Jeff J. Subleski et al. JOURNAL OF HEPATOLOGY
- Viral Infection of Tumors Overcomes Resistance to PD-1-immunotherapy by Broadening Neoantigenome-directed T-cell Responses
- (2015) Norman Woller et al. MOLECULAR THERAPY
- An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis
- (2015) Thomas Reiberger et al. Nature Protocols
- Neoantigens in cancer immunotherapy
- (2015) T. N. Schumacher et al. SCIENCE
- The Microsatellite Instable Subset of Colorectal Cancer Is a Particularly Good Candidate for Checkpoint Blockade Immunotherapy
- (2015) Yanping Xiao et al. Cancer Discovery
- Nonalcoholic Steatohepatitis: A Search for Factual Animal Models
- (2015) Sheila Cristina L. Sanches et al. Biomed Research International
- HCV infection-associated hepatocellular carcinoma in humanized mice
- (2015) Zhao Wang et al. Infectious Agents and Cancer
- Fast food diet with CCl4 micro-dose induced hepatic-fibrosis –a novel animal model
- (2014) Tarak K Chheda et al. BMC GASTROENTEROLOGY
- ER Stress Cooperates with Hypernutrition to Trigger TNF-Dependent Spontaneous HCC Development
- (2014) Hayato Nakagawa et al. CANCER CELL
- Metabolic Activation of Intrahepatic CD8+ T Cells and NKT Cells Causes Nonalcoholic Steatohepatitis and Liver Cancer via Cross-Talk with Hepatocytes
- (2014) Monika Julia Wolf et al. CANCER CELL
- Persistent hepatitis C virus infections and hepatopathological manifestations in immune-competent humanized mice
- (2014) Jizheng Chen et al. CELL RESEARCH
- Development of T Cells Redirected to Glypican-3 for the Treatment of Hepatocellular Carcinoma
- (2014) H. Gao et al. CLINICAL CANCER RESEARCH
- Agonistic anti-CD137 antibody treatment leads to antitumor response in mice with liver cancer
- (2014) Vanessa Gauttier et al. INTERNATIONAL JOURNAL OF CANCER
- CRISPR-mediated direct mutation of cancer genes in the mouse liver
- (2014) Wen Xue et al. NATURE
- PD-1 blockade induces responses by inhibiting adaptive immune resistance
- (2014) Paul C. Tumeh et al. NATURE
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- (2014) Tatsuhiro Shibata et al. Nature Reviews Gastroenterology & Hepatology
- Extensive double humanization of both liver and hematopoiesis in FRGN mice
- (2014) Elizabeth M. Wilson et al. Stem Cell Research
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- (2014) Tobias Eggert et al. Journal for ImmunoTherapy of Cancer
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- (2013) Qianjun Zhou et al. CANCER LETTERS
- Hepatocellular Carcinoma from an Immunologic Perspective
- (2013) T. F. Greten et al. CLINICAL CANCER RESEARCH
- Alcoholic Hepatitis: Current Challenges and Future Directions
- (2013) Ashwani K. Singal et al. Clinical Gastroenterology and Hepatology
- Role of the Microenvironment in the Pathogenesis and Treatment of Hepatocellular Carcinoma
- (2013) Virginia Hernandez–Gea et al. GASTROENTEROLOGY
- Adjuvant gemcitabine therapy improves survival in a locally induced, R0-resectable model of metastatic intrahepatic cholangiocarcinoma
- (2013) Engin Gürlevik et al. HEPATOLOGY
- An improved mouse model that rapidly develops fibrosis in non-alcoholic steatohepatitis
- (2013) Masahiko Matsumoto et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
- (2013) Bruno Sangro et al. JOURNAL OF HEPATOLOGY
- Regulation of accumulation and function of myeloid derived suppressor cells in different murine models of hepatocellular carcinoma
- (2013) Tamar Kapanadze et al. JOURNAL OF HEPATOLOGY
- Altered profile of human gut microbiome is associated with cirrhosis and its complications
- (2013) Jasmohan S. Bajaj et al. JOURNAL OF HEPATOLOGY
- Prevalence and Trends of Metabolic Syndrome in the Adult U.S. Population, 1999–2010
- (2013) Hiram Beltrán-Sánchez et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Mouse models for liver cancer
- (2013) Latifa Bakiri et al. Molecular Oncology
- Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
- (2013) Shin Yoshimoto et al. NATURE
- Completion of the entire hepatitis C virus life cycle in genetically humanized mice
- (2013) Marcus Dorner et al. NATURE
- Mouse model of chronic and binge ethanol feeding (the NIAAA model)
- (2013) Adeline Bertola et al. Nature Protocols
- Synergistic function of Kras mutation and HBx in initiation and progression of hepatocellular carcinoma in mice
- (2013) H Ye et al. ONCOGENE
- Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma
- (2013) M. Feng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Mechanisms of Fibrosis-Associated Promotion of Liver Carcinogenesis
- (2013) Takeki Uehara et al. TOXICOLOGICAL SCIENCES
- Value of α-fetoprotein in association with clinicopathological features of hepatocellular carcinoma
- (2013) Chang Liu WORLD JOURNAL OF GASTROENTEROLOGY
- Antigen-Specific T-Cell Activation Independently of the MHC: Chimeric Antigen Receptor-Redirected T Cells
- (2013) Markus Chmielewski et al. Frontiers in Immunology
- Animal models of chronic liver diseases
- (2012) Yan Liu et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4
- (2012) Dianne H. Dapito et al. CANCER CELL
- Disruption of Trp53 in Livers of Mice Induces Formation of Carcinomas With Bilineal Differentiation
- (2012) Sarah–Fee Katz et al. GASTROENTEROLOGY
- Natural killer cells in liver disease
- (2012) Zhigang Tian et al. HEPATOLOGY
- Combination therapy of radiofrequency ablation and bevacizumab monitored with power Doppler ultrasound in a murine model of hepatocellular carcinoma
- (2012) Ashesh A. Thaker et al. INTERNATIONAL JOURNAL OF HYPERTHERMIA
- Mouse intragastric infusion (iG) model
- (2012) Akiko Ueno et al. Nature Protocols
- Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
- (2012) Julie R. Brahmer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase 1 Study of Stereotactic Body Radiotherapy and Interleukin-2--Tumor and Immunological Responses
- (2012) S. K. Seung et al. Science Translational Medicine
- Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
- (2012) Yoshihisa Takahashi WORLD JOURNAL OF GASTROENTEROLOGY
- Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition
- (2011) Michael Charlton et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Animal models for the study of hepatic fibrosis
- (2011) Peter Starkel et al. BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY
- Critical Appraisal of the Side Population Assay in Stem Cell and Cancer Stem Cell Research
- (2011) Anna Golebiewska et al. Cell Stem Cell
- An Experimental Mouse Model for Hepatitis C Virus
- (2011) Kiminori KIMURA et al. EXPERIMENTAL ANIMALS
- An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice
- (2011) Pranoti Mandrekar et al. HEPATOLOGY
- A genetically humanized mouse model for hepatitis C virus infection
- (2011) Marcus Dorner et al. NATURE
- Hepatocellular carcinoma: insight from animal models
- (2011) Yan Li et al. Nature Reviews Gastroenterology & Hepatology
- Micro-CT Based Experimental Liver Imaging Using a Nanoparticulate Contrast Agent: A Longitudinal Study in Mice
- (2011) Hanne Boll et al. PLoS One
- Sex-related efficiency in NSG mouse engraftment
- (2010) I. Martin-Padura et al. BLOOD
- Engraftment of human hematopoietic stem cells is more efficient in female NOD/SCID/IL-2Rgc-null recipients
- (2010) F. Notta et al. BLOOD
- Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression
- (2010) Eek Joong Park et al. CELL
- Complement and Alcoholic Liver Disease: Role of C1q in the Pathogenesis of Ethanol-Induced Liver Injury in Mice
- (2010) Jessica I. Cohen et al. GASTROENTEROLOGY
- Antitumoural immunity by virus-mediated immunogenic apoptosis inhibits metastatic growth of hepatocellular carcinoma
- (2010) B. Boozari et al. GUT
- Liver antigen-presenting cells
- (2010) Ian Nicholas Crispe JOURNAL OF HEPATOLOGY
- Application of magnetic resonance imaging in transgenic and chemical mouse models of hepatocellular carcinoma
- (2010) Julia Freimuth et al. Molecular Cancer
- Animal models of nonalcoholic fatty liver disease
- (2010) Lionel Hebbard et al. Nature Reviews Gastroenterology & Hepatology
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene
- (2009) Dawang Zhou et al. CANCER CELL
- Glypican-3 expression is correlated with poor prognosis in hepatocellular carcinoma
- (2009) Hirofumi Shirakawa et al. CANCER SCIENCE
- c-Jun N-terminal Kinase-1 From Hematopoietic Cells Mediates Progression From Hepatic Steatosis to Steatohepatitis and Fibrosis in Mice
- (2009) Yuzo Kodama et al. GASTROENTEROLOGY
- Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice
- (2009) Astrid Spruss et al. HEPATOLOGY
- Diet-induced hepatocellular carcinoma in genetically predisposed mice
- (2009) A. E. Hill-Baskin et al. HUMAN MOLECULAR GENETICS
- Experimental mouse models for hepatocellular carcinoma research
- (2009) Femke Heindryckx et al. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
- Application of micro-CT in small animal imaging
- (2009) Sebastian J. Schambach et al. METHODS
- Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
- (2009) Alexander Ploss et al. NATURE
- Role of Alcohol in Liver Carcinogenesis
- (2009) Iain McKillop et al. SEMINARS IN LIVER DISEASE
- Glypican 3 Expression in Human Nonneoplastic, Preneoplastic, and Neoplastic Tissues
- (2008) Daniel Baumhoer et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- The Transition from Fatty Liver to NASH Associates with SAMe Depletion in db/db Mice Fed a Methionine Choline-Deficient Diet
- (2008) Matthew Wortham et al. DIGESTIVE DISEASES AND SCIENCES
- Mouse xenograft models vs GEM models for human cancer therapeutics
- (2008) A. Richmond et al. Disease Models & Mechanisms
- A phase II study of adoptive immunotherapy using dendritic cells pulsed with tumor lysate in patients with hepatocellular carcinoma
- (2008) Daniel H. Palmer et al. HEPATOLOGY
- Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development
- (2008) Silke Marhenke et al. HEPATOLOGY
- Fructose consumption as a risk factor for non-alcoholic fatty liver disease
- (2008) Xiaosen Ouyang et al. JOURNAL OF HEPATOLOGY
- Experimental models of hepatocellular carcinoma
- (2008) Philippa Newell et al. JOURNAL OF HEPATOLOGY
- Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice
- (2008) Rebeca Salguero Palacios et al. LABORATORY INVESTIGATION
- CYP2E1 and oxidative liver injury by alcohol
- (2007) Yongke Lu et al. FREE RADICAL BIOLOGY AND MEDICINE
- Interstrain differences in susceptibility to non-alcoholic steatohepatitis
- (2007) Yuichi Yamazaki et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
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