Genome‐wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

(2020) Connor A. Emdin et al.   PLoS Genetics

Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis

(2020) Tom G. Richardson et al.   PLOS MEDICINE

Polygenic Hyperlipidemias and Coronary Artery Disease Risk

(2020) Pietari Ripatti et al.   Circulation-Genomic and Precision Medicine

The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits

(2019) Sanghoon Moon et al.   Scientific Reports

Genome‐Wide Association Study Identifies Loci for Liver Enzyme Concentrations in Mexican Americans: The GUARDIAN Consortium

(2019) Kendra A. Young et al.   Obesity

A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease

(2018) Noura S. Abul-Husn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

(2018) Wei Zhou et al.   NATURE GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

NAFLD: PNPLA3 and obesity: a synergistic relationship in NAFLD

(2017) Jake P. Mann et al.   Nature Reviews Gastroenterology & Hepatology

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

Genome-wide analysis of health-related biomarkers in the UK Household Longitudinal Study reveals novel associations

(2017) Bram P. Prins et al.   Scientific Reports

Prevalence of chronic liver disease and cirrhosis by underlying cause in understudied ethnic groups: The multiethnic cohort

(2016) Veronica Wendy Setiawan et al.   HEPATOLOGY

Next-generation genotype imputation service and methods

(2016) Sayantan Das et al.   NATURE GENETICS

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

(2016) Frederick E. Dewey et al.   SCIENCE

Recommendations for Diagnosis, Referral for Liver Biopsy, and Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

(2015) Erin K. Spengler et al.   MAYO CLINIC PROCEEDINGS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation

(2015) Nuala A. O'Leary et al.   NUCLEIC ACIDS RESEARCH

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

(2015) et al.   SCIENCE

Liver enzymes, metabolomics and genome-wide association studies: From systems biology to the personalized medicine

(2015) Silvia Sookoian et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals

(2014) Yu-Cheng Lin et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

PRIMUS: Rapid Reconstruction of Pedigrees from Genome-wide Estimates of Identity by Descent

(2014) Jeffrey Staples et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The PNPLA3 Ile148Met interacts with overweight and dietary intakes on fasting triglyceride levels

(2014) Ivana A. Stojkovic et al.   Genes and Nutrition

Prevalence of Childhood and Adult Obesity in the United States, 2011-2012

(2014) Cynthia L. Ogden et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome

(2014) Hannele Yki-Järvinen   Lancet Diabetes & Endocrinology

Association of Polymorphisms in Glutamate-Cysteine Ligase Catalytic Subunit and Microsomal Triglyceride Transfer Protein Genes with Nonalcoholic Fatty Liver Disease

(2011) Mohammad Hashemi et al.   DNA AND CELL BIOLOGY

The Association of PNPLA3 Variants with Liver Enzymes in Childhood Obesity Is Driven by the Interaction with Abdominal Fat

(2011) Emanuele Miraglia del Giudice et al.   PLoS One

Microsomal triglyceride transfer protein and nonalcoholic fatty liver disease

(2011) Isabel VA Pereira et al.   Expert Review of Gastroenterology & Hepatology

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications

(2009) Elisa Fabbrini et al.   HEPATOLOGY

Genetic factors contribute to variation in serum alanine aminotransferase activity independent of obesity and alcohol: A study in monozygotic and dizygotic twins

(2009) Janne Makkonen et al.   JOURNAL OF HEPATOLOGY

Epidemiology and Genetic Epidemiology of the Liver Function Test Proteins

(2009) Nilufer Rahmioglu et al.   PLoS One

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

(2008) Stefano Romeo et al.   NATURE GENETICS