- Home
- Publications
- Publication Search
- Publication Details
Title
Up-down regulation of HIF-1α in cancer progression
Authors
Keywords
HIF-1α, Cancer progression, Invasion and metastasis, Cancer stem cells, Proliferation and apoptosis, Drug resistance
Journal
GENE
Volume 798, Issue -, Pages 145796
Publisher
Elsevier BV
Online
2021-06-25
DOI
10.1016/j.gene.2021.145796
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mitochondrial TCA cycle metabolites control physiology and disease
- (2020) Inmaculada Martínez-Reyes et al. Nature Communications
- The Role of Circulating Tumor Cells in the Metastatic Cascade: Biology, Technical Challenges, and Clinical Relevance
- (2020) Hassan Dianat-Moghadam et al. Cancers
- Impact of hypoxia on DNA repair and genome integrity
- (2019) Alanna R Kaplan et al. MUTAGENESIS
- Epigenetic Regulation of p21cip1/waf1 in Human Cancer
- (2019) Matthias Ocker et al. Cancers
- Succinate induces synovial angiogenesis in rheumatoid arthritis through metabolic remodeling and HIF-1α/VEGF axis
- (2018) Yi Li et al. FREE RADICAL BIOLOGY AND MEDICINE
- Hepatitis transactivator protein X promotes extracellular matrix modification through HIF/LOX pathway in liver cancer
- (2018) Aki Pui-Wah Tse et al. Oncogenesis
- C/EBPδ links IL-6 and HIF-1 signaling to promote breast cancer stem cell-associated phenotypes
- (2018) Kuppusamy Balamurugan et al. ONCOGENE
- HIF-1α-induced miR-23a∼27a∼24 cluster promotes colorectal cancer progression via reprogramming metabolism
- (2018) Fangfang Jin et al. CANCER LETTERS
- HIF-1α-derived cell-penetrating peptides inhibit ERK-dependent activation of HIF-1 and trigger apoptosis of cancer cells under hypoxia
- (2018) Angeliki Karagiota et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Drug Resistance Driven by Cancer Stem Cells and Their Niche
- (2017) Marta Prieto-Vila et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Expression of Hypoxia-Associated Protein HIF-1α in Follicular Thyroid Cancer is Associated with Distant Metastasis
- (2017) Aumayr Klaus et al. PATHOLOGY & ONCOLOGY RESEARCH
- Alpha-linolenic acid stabilizes HIF-1 α and downregulates FASN to promote mitochondrial apoptosis for mammary gland chemoprevention
- (2017) Subhadeep Roy et al. Oncotarget
- The impact of hypoxia on tumor-associated macrophages
- (2016) Anne-Theres Henze et al. JOURNAL OF CLINICAL INVESTIGATION
- Cancer metabolism: a therapeutic perspective
- (2016) Ubaldo E. Martinez-Outschoorn et al. Nature Reviews Clinical Oncology
- The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression
- (2016) Jiandong Chen Cold Spring Harbor Perspectives in Medicine
- Pathophysiological Basis for the Formation of the Tumor Microenvironment
- (2016) Michael R. Horsman et al. Frontiers in Oncology
- HIF-1 at the crossroads of hypoxia, inflammation, and cancer
- (2015) Kuppusamy Balamurugan INTERNATIONAL JOURNAL OF CANCER
- Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H+ symporters
- (2015) Ibtissam Marchiq et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- HIF-1α mediates Hypoxia-induced epithelial–mesenchymal transition in peritoneal mesothelial cells
- (2015) Yoshiyuki Morishita et al. RENAL FAILURE
- T cell exclusion, immune privilege, and the tumor microenvironment
- (2015) J. A. Joyce et al. SCIENCE
- Biology of Hypoxia
- (2015) Paul N. Span et al. SEMINARS IN NUCLEAR MEDICINE
- Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3
- (2014) Meghan B. Azad et al. Autophagy
- HIF-1 can act as a tumor suppressor gene in murine acute myeloid leukemia
- (2014) T. Velasco-Hernandez et al. BLOOD
- Evolution of the Cancer Stem Cell Model
- (2014) Antonija Kreso et al. Cell Stem Cell
- Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1α/miR-210/Bcl-2 pathway in colon cancer cells
- (2014) YONG SUN et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Preclinical evaluation of bortezomib/dipyridamole novel combination as a potential therapeutic modality for hematologic malignancies
- (2014) Ahmed E. Goda et al. Molecular Oncology
- Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
- (2014) Antonina V. Kurtova et al. NATURE
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Critical Role of Aberrant Angiogenesis in the Development of Tumor Hypoxia and Associated Radioresistance
- (2014) Gabriele Multhoff et al. Cancers
- Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
- (2013) Gregg L. Semenza Annual Review of Pathology-Mechanisms of Disease
- A Mechanism of Hypoxia-Mediated Escape from Adaptive Immunity in Cancer Cells
- (2013) I. B. Barsoum et al. CANCER RESEARCH
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- A mathematical model of HiF-1-mediated response to hypoxia on the G1/S transition
- (2013) B. Bedessem et al. MATHEMATICAL BIOSCIENCES
- Catabolism of Exogenous Lactate Reveals It as a Legitimate Metabolic Substrate in Breast Cancer
- (2013) Kelly M. Kennedy et al. PLoS One
- Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
- (2012) Y.-L. Hu et al. CANCER RESEARCH
- Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
- (2012) Yan Xia et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- M2 isoform of pyruvate kinase is dispensable for tumor maintenance and growth
- (2012) M. Cortes-Cros et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The VHL/HIF axis in clear cell renal carcinoma
- (2012) Chuan Shen et al. SEMINARS IN CANCER BIOLOGY
- Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
- (2012) Gregg L. Semenza TRENDS IN PHARMACOLOGICAL SCIENCES
- Lactate: A Metabolic Key Player in Cancer
- (2011) F. Hirschhaeuser et al. CANCER RESEARCH
- Pyruvate Kinase Triggers a Metabolic Feedback Loop that Controls Redox Metabolism in Respiring Cells
- (2011) Nana-Maria Grüning et al. Cell Metabolism
- p38 MAPK regulates G1-S transition in hypoxic cardiac fibroblasts
- (2011) Malini S. Pillai et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Bortezomib represses HIF-1α protein expression and nuclear accumulation by inhibiting both PI3K/Akt/TOR and MAPK pathways in prostate cancer cells
- (2011) Christina D. Befani et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
- (2011) D. Anastasiou et al. SCIENCE
- Revisiting the TCA cycle: signaling to tumor formation
- (2011) Nuno Raimundo et al. TRENDS IN MOLECULAR MEDICINE
- Genetic and Functional Studies Implicate HIF1 as a 14q Kidney Cancer Suppressor Gene
- (2011) C. Shen et al. Cancer Discovery
- Hypoxia. 2. Hypoxia regulates cellular metabolism
- (2010) William W. Wheaton et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- In vivo Dynamics and Distinct Functions of Hypoxia in Primary Tumor Growth and Organotropic Metastasis of Breast Cancer
- (2010) X. Lu et al. CANCER RESEARCH
- The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
- (2010) John M. Heddleston et al. CELL CYCLE
- Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis
- (2010) X. Lu et al. CLINICAL CANCER RESEARCH
- AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells
- (2010) L. Harhaji-Trajkovic et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Apigenin Down-Regulates the Hypoxia Response Genes: HIF-1α, GLUT-1, and VEGF in Human Pancreatic Cancer Cells
- (2010) Laleh G. Melstrom et al. JOURNAL OF SURGICAL RESEARCH
- Hypoxia and RAS-signaling pathways converge on and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs
- (2010) F Loayza-Puch et al. ONCOGENE
- Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells
- (2009) Zhizhong Li et al. CANCER CELL
- Ansamycin Inhibitors of Hsp90: Natures Prototype for Anti-Chaperone Therapy
- (2009) James Porter et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex
- (2009) Johannes von Burstin et al. GASTROENTEROLOGY
- FM19G11, a New Hypoxia-inducible Factor (HIF) Modulator, Affects Stem Cell Differentiation Status
- (2009) Victoria Moreno-Manzano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Development of HIF-1 inhibitors for cancer therapy
- (2009) Barbara Onnis et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Role of hypoxia in the hallmarks of human cancer
- (2009) Kai Ruan et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Physiologic Oxygen Concentration Enhances the Stem-Like Properties of CD133+ Human Glioblastoma Cells In vitro
- (2009) A. M. McCord et al. MOLECULAR CANCER RESEARCH
- Increased antitumor activity of bevacizumab in combination with hypoxia inducible factor-1 inhibition
- (2009) A. Rapisarda et al. MOLECULAR CANCER THERAPEUTICS
- Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
- (2009) G L Semenza ONCOGENE
- Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α
- (2009) A Soeda et al. ONCOGENE
- Pluripotent Transcription Factors Possess Distinct Roles in Normal versus Transformed Human Stem Cells
- (2009) Junfeng Ji et al. PLoS One
- Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells
- (2009) K. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Low Oxygen Enhances Primitive and Definitive Neural Stem Cell Colony Formation by Inhibiting Distinct Cell Death Pathways
- (2009) Laura Clarke et al. STEM CELLS
- TGFβ Primes Breast Tumors for Lung Metastasis Seeding through Angiopoietin-like 4
- (2008) David Padua et al. CELL
- Novel Delivery of SN38 Markedly Inhibits Tumor Growth in Xenografts, Including a Camptothecin-11-Refractory Model
- (2008) P. Sapra et al. CLINICAL CANCER RESEARCH
- Chemosensitization of Cancer by Nitric Oxide
- (2008) Richard Sullivan et al. CURRENT PHARMACEUTICAL DESIGN
- PX-478, an inhibitor of hypoxia-inducible factor-1α, enhances radiosensitivity of prostate carcinoma cells
- (2008) Sanjeewani T. Palayoor et al. INTERNATIONAL JOURNAL OF CANCER
- Survival of the Fittest: Cancer Stem Cells in Therapeutic Resistance and Angiogenesis
- (2008) Christine E. Eyler et al. JOURNAL OF CLINICAL ONCOLOGY
- Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study
- (2008) Roy Vergis et al. LANCET ONCOLOGY
- Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1
- (2008) M. Y. Koh et al. MOLECULAR CANCER THERAPEUTICS
- Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity
- (2008) R. Sullivan et al. MOLECULAR CANCER THERAPEUTICS
- A RNA antagonist of hypoxia-inducible factor-1 , EZN-2968, inhibits tumor cell growth
- (2008) L. M. Greenberger et al. MOLECULAR CANCER THERAPEUTICS
- An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors
- (2008) Ittai Ben-Porath et al. NATURE GENETICS
- Silibinin inhibits hypoxia-inducible factor-1α and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy
- (2008) P García-Maceira et al. ONCOGENE
- Hypoxia Enhances Tumor Stemness by Increasing the Invasive and Tumorigenic Side Population Fraction
- (2008) Bikul Das et al. STEM CELLS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now