Novel N-bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis, in vitro and in silico studies
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Novel N-bridged pyrazole-1-carbothioamides with potential antiproliferative activity: design, synthesis, in vitro and in silico studies
Authors
Keywords
-
Journal
Future Medicinal Chemistry
Volume -, Issue -, Pages -
Publisher
Future Science Ltd
Online
2021-08-24
DOI
10.4155/fmc-2021-0066
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- New Mononuclear and Binuclear Cu(II), Co(II), Ni(II), and Zn(II) Thiosemicarbazone Complexes with Potential Biological Activity: Antimicrobial and Molecular Docking Study
- (2021) Ahmed Gaber et al. MOLECULES
- Stereoselective Synthesis of Novel Sphingoid Bases Utilized for Exploring the Secrets of Sphinx
- (2021) Essa M. Saied et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Pyrazoles and Pyrazolines as Anti-Inflammatory Agents
- (2021) Martha Mantzanidou et al. MOLECULES
- Design, synthesis, and pharmacological evaluation of 4- or 6-phenyl-pyrimidine derivatives as novel and selective Janus kinase 3 inhibitors
- (2020) Lei Shu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses
- (2020) Valeria Francesconi et al. MOLECULES
- Design, Synthesis, and Antimicrobial Evaluation of New Annelated Pyrimido[2,1-c][1,2,4]triazolo[3,4-f][1,2,4]triazines
- (2020) Islam H. El Azab et al. MOLECULES
- Subunit composition of the mammalian serine-palmitoyltransferase defines the spectrum of straight and methyl-branched long-chain bases
- (2020) Museer A. Lone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel Papaverine Metal Complexes with Potential Anticancer Activities
- (2020) Ahmed Gaber et al. MOLECULES
- Design, synthesis, and apoptosis-promoting effect evaluation of novel pyrazole with benzo[d]thiazole derivatives containing aminoguanidine units
- (2019) Da Chuan Liu et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Structure-based design, synthesis and biological evaluation of a newer series of pyrazolo[1,5-a]pyrimidine analogues as potential anti-tubercular agents
- (2019) Palmi Modi et al. BIOORGANIC CHEMISTRY
- Thiazolyl-pyrazole derivatives as potential antimycobacterial agents
- (2019) Sushma J. Takate et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of nitroxide labeled pyrimidines as Aurora kinase inhibitors
- (2019) You-Zhen Ma et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthetic approaches and pharmaceutical applications of chloro-containing molecules for drug discovery: A critical review
- (2019) Wan-Yin Fang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities
- (2019) Fang Yang et al. BIOORGANIC CHEMISTRY
- Discovery of novel pyrimidine-based benzothiazole derivatives as potent cyclin-dependent kinase 2 inhibitors with anticancer activity
- (2019) Peng-Cheng Diao et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design, synthesis and biological evaluation of 2-(4-alkoxy-3-cyano)phenyl-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives as novel xanthine oxidase inhibitors
- (2019) Qing Mao et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors
- (2019) Sravani Sana et al. BIOORGANIC CHEMISTRY
- 1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships
- (2019) Zhi Xu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design, synthesis, biological evaluation and molecular docking study of novel thieno[3,2-d]pyrimidine derivatives as potent FAK inhibitors
- (2019) Ruifeng Wang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- 2-Substituted-1-(2-morpholinoethyl)-1 H -naphtho[2,3- d ]imidazole-4,9-diones: Design, synthesis and antiproliferative activity
- (2018) Zhanxiong Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi-target inhibitors for the treatment of non-small cell lung cancer
- (2018) Andrea Bistrović et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Kinase-targeted cancer therapies: progress, challenges and future directions
- (2018) Khushwant S. Bhullar et al. Molecular Cancer
- Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma
- (2018) Roland Sonntag et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclin-Dependent Kinase 2 Inhibitors in Cancer Therapy: An Update
- (2018) Solomon Tadesse et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure of a human intramembrane ceramidase explains enzymatic dysfunction found in leukodystrophy
- (2018) Ieva Vasiliauskaité-Brooks et al. Nature Communications
- Synthesis, in silico experiments and biological evaluation of 1,3,4-trisubstituted pyrazole derivatives as antimalarial agents
- (2018) Adnan A. Bekhit et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design, synthesis, modeling studies and biological evaluation of thiazolidine derivatives containing pyrazole core as potential anti-diabetic PPAR-γ agonists and anti-inflammatory COX-2 selective inhibitors
- (2018) Khaled R.A. Abdellatif et al. BIOORGANIC CHEMISTRY
- Recent advances of pyrazole-containing derivatives as anti-tubercular agents
- (2017) Zhi Xu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Antimicrobial Activity of Novel Azolopyrimidines and Pyrido-Triazolo-Pyrimidinones Incorporating Pyrazole Moiety
- (2017) Ikhlass M. Abbas et al. JOURNAL OF HETEROCYCLIC CHEMISTRY
- Substituted N-Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery
- (2017) Elisa Azzali et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Activity of the Neutral Sphingomyelinase Is Important in T Cell Recruitment and Directional Migration
- (2017) Lena Collenburg et al. Frontiers in Immunology
- Cytoplasmic Cyclin E and Phospho–Cyclin-Dependent Kinase 2 Are Biomarkers of Aggressive Breast Cancer
- (2016) Cansu Karakas et al. AMERICAN JOURNAL OF PATHOLOGY
- Mycobacterium Tuberculosis (MTB) GyrB inhibitors: An attractive approach for developing novel drugs against TB
- (2016) Kavita Chaudhari et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Recent developments of C-4 substituted coumarin derivatives as anticancer agents
- (2016) Jyoti Dandriyal et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Pyrazole clubbed triazolo[1,5-a]pyrimidine hybrids as an anti-tubercular agents: Synthesis, in vitro screening and molecular docking study
- (2015) Jaimin D. Bhatt et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and biological evaluation of pyrazolylthiazole carboxylic acids as potent anti-inflammatory–antimicrobial agents
- (2015) Poonam Khloya et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis, biological activity evaluation and molecular docking studies of novel coumarin substituted thiazolyl-3-aryl-pyrazole-4-carbaldehydes
- (2015) Krishnaiah Vaarla et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A series of ceramide analogs modified at the 1-position with potent activity against the intracellular growth of Chlamydia trachomatis
- (2015) Essa M Saied et al. Future Medicinal Chemistry
- Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1)
- (2015) Zhanping Lu et al. Oncotarget
- Facile Synthesis of the CERT Inhibitor HPA-12 and Some Novel Derivatives
- (2014) Essa M. Saied et al. Chemistry-An Asian Journal
- Crystal Structure of Sphingosine Kinase 1 with PF-543
- (2014) Jing Wang et al. ACS Medicinal Chemistry Letters
- Synthesis, molecular docking and evaluation of thiazolyl-pyrazoline derivatives containing benzodioxole as potential anticancer agents
- (2012) Hai-Hong Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
- (2012) M. Nagahashi et al. CANCER RESEARCH
- Synthesis and anti-tumor activity of novel ethyl 3-aryl-4-oxo-3,3a,4,6-tetrahydro-1H-furo[3,4-c]pyran-3a-carboxylates
- (2011) Tiantian Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis of rotenoid derivatives with cytotoxic and topoisomerase II inhibitory activities
- (2011) Supranee Sangthong et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of 1-substituted-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors
- (2011) Cheng Hua Jin et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Cytotoxicity of some Cameroonian spices and selected medicinal plant extracts
- (2011) Victor Kuete et al. JOURNAL OF ETHNOPHARMACOLOGY
- Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG1 axis in hepatocellular carcinoma
- (2011) Meiyan Bao et al. LIVER INTERNATIONAL
- Synthesis and biological evaluation of 2-pyridyl-substituted pyrazoles and imidazoles as transforming growth factor-β type 1 receptor kinase inhibitors
- (2010) Purushottam M. Dewang et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Sensitivity and resistance towards isoliquiritigenin, doxorubicin and methotrexate in T cell acute lymphoblastic leukaemia cell lines by pharmacogenomics
- (2010) Mahmoud Youns et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Synthesis and biological evaluation of some nitrogen containing steroidal heterocycles
- (2010) Mervat M. Abdelhalim et al. STEROIDS
- Synthesis and biological evaluation of a novel series of pyrazole chalcones as anti-inflammatory, antioxidant and antimicrobial agents
- (2009) Babasaheb P. Bandgar et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Microwave assisted synthesis of new indophenazine 1,3,5-trisubstruted pyrazoline derivatives of benzofuran and their antimicrobial activity
- (2009) Kuntal Manna et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist
- (2009) Atsushi Satoh et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Antiproliferative and Proapoptotic Activities of a New Class of Pyrazole Derivatives in HL-60 Cells
- (2009) Maria Anzaldi et al. CHEMISTRY & BIODIVERSITY
- Synthesis and anticancer activity of N-bis(trifluoromethyl)alkyl-N′-thiazolyl and N-bis(trifluoromethyl)alkyl-N′-benzothiazolyl ureas
- (2009) Elena L. Luzina et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and in vitro anticancer activity of 2,4-azolidinedione-acetic acids derivatives
- (2009) Danylo Kaminskyy et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Spectroscopic and Thermal Studies of Mn(II), Fe(III), Cr(III) and Zn(II) Complexes Derived from the Ligand Resulted by the Reaction Between 4-Acetyl Pyridine and Thiosemicarbazide
- (2009) Moamen S. Refat et al. Journal of Inorganic and Organometallic Polymers and Materials
- Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus
- (2009) Jason M. Uslaner et al. NEUROPHARMACOLOGY
- The role of sphingosine kinase 1 in cancer: Oncogene or non-oncogene addiction?
- (2008) M VADAS BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Synthesis and antiviral evaluation of some new pyrazole and fused pyrazolopyrimidine derivatives
- (2008) Aymn E. Rashad et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis, structure and antibacterial activity of novel 1-(5-substituted-3-substituted-4,5-dihydropyrazol-1-yl)ethanone oxime ester derivatives
- (2008) Xin-Hua Liu et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis and antiviral activity of novel pyrazole derivatives containing oxime esters group
- (2008) Guiping Ouyang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Thiazolyl/oxazolyl formazanyl indoles as potent anti-inflammatory agents
- (2008) Nisha Singh et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis of novel thiazolone-based compounds containing pyrazoline moiety and evaluation of their anticancer activity
- (2008) Dmytro Havrylyuk et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Role for sphingosine kinase 1 in colon carcinogenesis
- (2008) Toshihiko Kawamori et al. FASEB JOURNAL
- Cost-Utility Analysis of Rimonabant in the Treatment of Obesity
- (2008) Christian Hampp et al. VALUE IN HEALTH
- Design and synthesis of 2-(2,6-dibromophenyl)-3-heteroaryl-1,3-thiazolidin-4-ones as anti-HIV agents
- (2007) Ravindra K. Rawal et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now