Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma

Loss of Cyclin E1 attenuates hepatitis and hepatocarcinogenesis in a mouse model of chronic liver injury

(2018) Haksier Ehedego et al.   ONCOGENE

Kinase-independent function of E-type cyclins in liver cancer

(2018) Yan Geng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting CCl4 -induced liver fibrosis by RNA interference-mediated inhibition of cyclin E1 in mice

(2017) Jörg-Martin Bangen et al.   HEPATOLOGY

Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma

(2017) Lindsey N. Kent et al.   JOURNAL OF CLINICAL INVESTIGATION

Prognostic Biomarker Identification Through Integrating the Gene Signatures of Hepatocellular Carcinoma Properties

(2017) Jialin Cai et al.   EBioMedicine

ECT2 regulates the Rho/ERK signalling axis to promote early recurrence in human hepatocellular carcinoma

(2015) Jianxiang Chen et al.   JOURNAL OF HEPATOLOGY

The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations

(2014) Xavier Bisteau et al.   Cancers

Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis

(2013) Yulia A. Nevzorova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Differences in regulation and function of E-cyclins in human cancer cells

(2013) Yan Geng et al.   CELL CYCLE

Concurrent deletion of cyclin E1 and cyclin-dependent kinase 2 in hepatocytes inhibits DNA replication and liver regeneration in mice

(2013) Wei Hu et al.   HEPATOLOGY

Nucleophosmin (NPM1/B23) Interacts with Activating Transcription Factor 5 (ATF5) Protein and Promotes Proteasome- and Caspase-dependent ATF5 Degradation in Hepatocellular Carcinoma Cells

(2012) Xijun Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation

(2011) Junko Odajima et al.   DEVELOPMENTAL CELL

Hepatocyte IKKβ/NF-κB Inhibits Tumor Promotion and Progression by Preventing Oxidative Stress-Driven STAT3 Activation

(2010) Guobin He et al.   CANCER CELL

Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer

(2010) C Caldon et al.   Cell Division

Aberrant Cell Cycle Progression and Endoreplication in Regenerating Livers of Mice That Lack a Single E-Type Cyclin

(2009) Yulia A. Nevzorova et al.   GASTROENTEROLOGY