Design, synthesis, and pharmacological evaluation of 4- or 6-phenyl-pyrimidine derivatives as novel and selective Janus kinase 3 inhibitors

Published 2020 View Full Article

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Title
Design, synthesis, and pharmacological evaluation of 4- or 6-phenyl-pyrimidine derivatives as novel and selective Janus kinase 3 inhibitors
Authors
Keywords
Autoimmune diseases, Covalent JAK3 inhibitors, Cys909, Janus kinase, 4- or 6-phenyl-pyrimidine derivatives
Journal
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Volume 191, Issue -, Pages 112148
Publisher
Elsevier BV
Online
2020-02-16
DOI
10.1016/j.ejmech.2020.112148

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