Activation of the Farnesoid X Receptor (FXR) Suppresses Linoleic Acid-Induced Inflammation in the Large Yellow Croaker (Larimichthys crocea)

High percentage of dietary palm oil suppressed growth and antioxidant capacity and induced the inflammation by activation of TLR-NF-κB signaling pathway in large yellow croaker (Larimichthys crocea)

(2019) Xueshan Li et al.   FISH & SHELLFISH IMMUNOLOGY

Molecular Cloning, Characterization, and Nutritional Regulation of Elovl6 in Large Yellow Croaker (Larimichthys crocea)

(2019) Yongnan Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

High level of dietary olive oil decreased growth, increased liver lipid deposition and induced inflammation by activating the p38 MAPK and JNK pathways in large yellow croaker (Larimichthys crocea)

(2019) Xueshan Li et al.   FISH & SHELLFISH IMMUNOLOGY

Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis and NLRP3 activation in mice

(2018) Susanne Schuster et al.   JOURNAL OF LIPID RESEARCH

Farnesoid X receptor agonist obeticholic acid inhibits renal inflammation and oxidative stress during lipopolysaccharide-induced acute kidney injury

(2018) Jin-Bo Zhu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Influence of a Dietary Vegetable Oil Blend on Serum Lipid Profiles in Large Yellow Croaker (Larimichthys crocea)

(2018) Si Zhu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dietary vegetable oil suppressed non-specific immunity and liver antioxidant capacity but induced inflammatory response in Japanese sea bass ( Lateolabrax japonicus )

(2017) Peng Tan et al.   FISH & SHELLFISH IMMUNOLOGY

Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammation

(2017) Yimeng Zhang et al.   TOXICOLOGY

Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea)

(2017) Songlin Li et al.   Scientific Reports

Vegetable oil induced inflammatory response by altering TLR-NF-κB signalling, macrophages infiltration and polarization in adipose tissue of large yellow croaker ( Larimichthys crocea )

(2016) Peng Tan et al.   FISH & SHELLFISH IMMUNOLOGY

Linoleic acid and the pathogenesis of obesity

(2016) Shaan S. Naughton et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Characterization of Cyclooxygenase-2 and its induction pathways in response to high lipid diet-induced inflammation in Larmichthys crocea

(2016) Tianjiao Wang et al.   Scientific Reports

Dietary vegetable oils: Effects on the expression of immune-related genes in Senegalese sole (Solea senegalensis) intestine

(2015) Daniel Montero et al.   FISH & SHELLFISH IMMUNOLOGY

Excessive dietary linoleic acid induces proinflammatory markers in rats

(2015) Justine Marchix et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Replacement of Fish Oil with Linseed Oil or Soybean Oil in Feeds for Japanese Seabass,Lateolabrax japonicus: Effects on Growth Performance, Immune Response, and Tissue Fatty Acid Composition

(2015) Houguo Xu et al.   JOURNAL OF THE WORLD AQUACULTURE SOCIETY

Farnesoid X receptor: a master regulator of hepatic triglyceride and glucose homeostasis

(2014) Yang Jiao et al.   ACTA PHARMACOLOGICA SINICA

Growth performance, lipid deposition and hepatic lipid metabolism related gene expression in juvenile turbot (Scophthalmus maximus L.) fed diets with various fish oil substitution levels by soybean oil

(2014) Mo Peng et al.   AQUACULTURE

Dietary ALA, But not LNA, Increase Growth, Reduce Inflammatory Processes, and Increase Anti-Oxidant Capacity in the Marine Finfish Larimichthys crocea

(2014) Rantao Zuo et al.   LIPIDS

FXR agonist GW4064 alleviates endotoxin-induced hepatic inflammation by repressing macrophage activation

(2014) Jun Yao   WORLD JOURNAL OF GASTROENTEROLOGY

The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species

(2011) Matthew D Krasowski et al.   BMC BIOCHEMISTRY

Effects of dietary n-3 highly unsaturated fatty acids on growth, nonspecific immunity, expression of some immune related genes and disease resistance of large yellow croaker (Larmichthys crocea) following natural infestation of parasites (Cryptocaryon irritans)

(2011) Rantao Zuo et al.   FISH & SHELLFISH IMMUNOLOGY

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

(2011) R. M. Gadaleta et al.   GUT

The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors

(2011) Jae-Min Yuk et al.   NATURE IMMUNOLOGY

Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro☆

(2010) Deanna L. Howarth et al.   AQUATIC TOXICOLOGY

Role of nuclear receptor SHP in metabolism and cancer

(2010) Yuxia Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Replacement of dietary fish oil by vegetable oils affects humoral immunity and expression of pro-inflammatory cytokines genes in gilthead sea bream Sparus aurata

(2010) D. Montero et al.   FISH & SHELLFISH IMMUNOLOGY

FXR Regulates Liver Repair after CCl4-Induced Toxic Injury

(2010) Zhipeng Meng et al.   MOLECULAR ENDOCRINOLOGY

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

(2009) P. Vavassori et al.   JOURNAL OF IMMUNOLOGY

Exposure to the synthetic FXR agonist GW4064 causes alterations in gene expression and sublethal hepatotoxicity in eleutheroembryo medaka (Oryzias latipes)

(2009) Deanna L. Howarth et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Farnesoid X receptor antagonizes nuclear factor κB in hepatic inflammatory response

(2008) Yan-Dong Wang et al.   HEPATOLOGY

Immunolocalization of farnesoid X receptor (FXR) in mouse tissues using tissue microarray

(2007) Hiroyuki Higashiyama et al.   ACTA HISTOCHEMICA

The opposing effects of n−3 and n−6 fatty acids

(2007) Gerd Schmitz et al.   PROGRESS IN LIPID RESEARCH