Unexpected beta-amyloid production by middle doses of resveratrol through stabilization of APP protein and AMPK-mediated inhibition of trypsin-like proteasome activity in a cell model of Alzheimer's disease

Potential Adverse Effects of Resveratrol: A Literature Review

(2020) Abdullah Shaito et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer’s disease

(2020) Claudia P. Boix et al.   Alzheimers Research & Therapy

The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition

(2019) Judith Hounjet et al.   ONCOGENE

Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity

(2019) Stella Kouloulia et al.   Cell Reports

Brain targeting of resveratrol by nasal administration of chitosan-coated lipid microparticles

(2018) Valentina Trotta et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Trichostatin A and Sirtinol Regulate the Expression and Nucleocytoplasmic Shuttling of Histone Deacetylases in All-Trans Retinoic Acid-Induced Differentiation of Neuroblastoma Cells

(2018) Bong-Geum Jang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Resveratrol Induces Brain Resilience Against Alzheimer Neurodegeneration Through Proteostasis Enhancement

(2018) Rubén Corpas et al.   MOLECULAR NEUROBIOLOGY

cAMP, cGMP and Amyloid β: Three Ideal Partners for Memory Formation

(2018) Roberta Ricciarelli et al.   TRENDS IN NEUROSCIENCES

Measurement of Altered AβPP Isoform Expression in Frontal Cortex of Patients with Alzheimer's Disease by Absolute Quantification Real-Time PCR

(2018) William G. Tharp et al.   JOURNAL OF ALZHEIMERS DISEASE

Different effect of resveratrol to induction of apoptosis depending on the type of human cancer cells

(2017) Michinori Takashina et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

(2017) Charbel Moussa et al.   Journal of Neuroinflammation

Resveratrol Downregulates Biomarkers of Sepsis via Inhibition of Proteasomeʼs Proteases

(2017) Neerupma Silswal et al.   SHOCK

Sirtinol promotes PEPCK1 degradation and inhibits gluconeogenesis by inhibiting deacetylase SIRT2

(2017) Mingming Zhang et al.   Scientific Reports

The paradoxical pro- and antiangiogenic actions of resveratrol: therapeutic applications in cancer and diabetes

(2016) Mohammad Amin Kamaleddin   Annals of the New York Academy of Sciences

AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs

(2016) D. Grahame Hardie et al.   TRENDS IN CELL BIOLOGY

Piceatannol, a natural analogue of resveratrol, effectively reduces beta-amyloid levels via activation of alpha-secretase and matrix metalloproteinase-9

(2016) Boyoung Choi et al.   Journal of Functional Foods

The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling

(2016) Gang Wang et al.   Oncotarget

Chloroquine and Chloroquinoline Derivatives as Models for the Design of Modulators of Amyloid Peptide Precursor Metabolism

(2015) Patricia Melnyk et al.   ACS Chemical Neuroscience

The molecular targets of resveratrol

(2015) Sameer S. Kulkarni et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sirtuin inhibitor sirtinol is an intracellular iron chelator

(2015) R. Gautam et al.   CHEMICAL COMMUNICATIONS

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease

(2015) R. Scott Turner et al.   NEUROLOGY

Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice

(2015) Hong Cai et al.   Science Translational Medicine

Compartmentalized AMPK Signaling Illuminated by Genetically Encoded Molecular Sensors and Actuators

(2015) Takafumi Miyamoto et al.   Cell Reports

SUMO1 promotes Aβ production via the modulation of autophagy

(2014) Sun-Jung Cho et al.   Autophagy

Minireview: Hey U(PS): Metabolic and Proteolytic Homeostasis Linked via AMPK and the Ubiquitin Proteasome System

(2014) Sarah M. Ronnebaum et al.   MOLECULAR ENDOCRINOLOGY

Resveratrol promotes proteasome-dependent degradation of Nanog via p53 activation and induces differentiation of glioma stem cells

(2013) Atsushi Sato et al.   Stem Cell Research

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

(2012) Sung-Jun Park et al.   CELL

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

FBL2 Regulates Amyloid Precursor Protein (APP) Metabolism by Promoting Ubiquitination-Dependent APP Degradation and Inhibition of APP Endocytosis

(2012) T. Watanabe et al.   JOURNAL OF NEUROSCIENCE

Phlorotannin-rich Ecklonia cava reduces the production of beta-amyloid by modulating alpha- and gamma-secretase expression and activity

(2012) Il-Jun Kang et al.   NEUROTOXICOLOGY

Ubiquilin-1 regulates amyloid precursor protein maturation and degradation by stimulating K63-linked polyubiquitination of lysine 688

(2012) A. El Ayadi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resveratrol as a calorie restriction mimetic: therapeutic implications

(2012) Jay H. Chung et al.   TRENDS IN CELL BIOLOGY

The specificities of small molecule inhibitors of the TGFß and BMP pathways

(2011) Janis Vogt et al.   CELLULAR SIGNALLING

Resveratrol, a Phytochemical Inducer of Multiple Cell Death Pathways: Apoptosis, Autophagy and Mitotic Catastrophe

(2011) D. Delmas et al.   CURRENT MEDICINAL CHEMISTRY

The controversial links among calorie restriction, SIRT1, and resveratrol

(2011) Yi Hu et al.   FREE RADICAL BIOLOGY AND MEDICINE

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Compound C induces protective autophagy in cancer cells through AMPK inhibition-independent blockade of Akt/mTOR pathway

(2010) Ljubica Vucicevic et al.   Autophagy

AMP-activated protein kinase and its downstream transcriptional pathways

(2010) Carles Cantó et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

In VitroBACE-1 Inhibitory Activity of Resveratrol Oligomers from the Seed Extract ofPaeonia lactiflora

(2010) Chun Choi et al.   PLANTA MEDICA

AMP-Activated Protein Kinase-Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

(2009) J.-H. Um et al.   DIABETES

Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway

(2009) Elizabeth D. Brookins Danz et al.   FREE RADICAL BIOLOGY AND MEDICINE

Resveratrol inhibits beta-amyloid oligomeric cytotoxicity but does not prevent oligomer formation

(2009) Ying Feng et al.   NEUROTOXICOLOGY