The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition
Authors
Keywords
-
Journal
ONCOGENE
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-04-09
DOI
10.1038/s41388-019-0802-x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells
- (2018) Jianghong Man et al. Cell Stem Cell
- CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk
- (2017) Pinjia Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis
- (2017) Ravshan Burikhanov et al. Cell Reports
- Autophagy inhibitor chloroquine increases sensitivity to cisplatin in QBC939 cholangiocarcinoma cells by mitochondrial ROS
- (2017) Xianzhi Qu et al. PLoS One
- Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres
- (2016) Manabu Natsumeda et al. BRAIN PATHOLOGY
- Research progress of hydroxychloroquine and autophagy inhibitors on cancer
- (2016) Ting-Ting Shi et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia
- (2015) Daniel Herranz et al. NATURE MEDICINE
- Notch is a direct negative regulator of the DNA-damage response
- (2015) Jelena Vermezovic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Chloroquine inhibits hepatocellular carcinoma cell growth in vitro and in vivo
- (2015) TAO HU et al. ONCOLOGY REPORTS
- Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
- (2015) Christina H. Eng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Autophagosome–lysosome fusion is independent of V-ATPase-mediated acidification
- (2015) Caroline Mauvezin et al. Nature Communications
- Notch is a direct negative regulator of the DNA-damage response
- (2015) Jelena Vermezovic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Tumor Vessel Normalization by Chloroquine Independent of Autophagy
- (2014) Hannelore Maes et al. CANCER CELL
- Mitochondrial membrane potential and reactive oxygen species in cancer stem cells
- (2014) Bei-bei Zhang et al. Familial Cancer
- Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells
- (2014) Yusuke S. Hori et al. JOURNAL OF NEURO-ONCOLOGY
- Suppression of autophagy by chloroquine sensitizes 5-fluorouracil-mediated cell death in gallbladder carcinoma cells
- (2014) Xiao Liang et al. Cell and Bioscience
- Complementary Genomic Screens Identify SERCA as a Therapeutic Target in NOTCH1 Mutated Cancer
- (2013) Giovanni Roti et al. CANCER CELL
- Chloroquine Engages the Immune System to Eradicate Irradiated Breast Tumors in Mice
- (2013) Josephine Anna Ratikan et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Notch-Nrf2 Axis: Regulation of Nrf2 Gene Expression and Cytoprotection by Notch Signaling
- (2013) N. Wakabayashi et al. MOLECULAR AND CELLULAR BIOLOGY
- Autophagy: shaping the tumor microenvironment and therapeutic response
- (2013) Hannelore Maes et al. TRENDS IN MOLECULAR MEDICINE
- Impaired endolysosomal function disrupts Notch signalling in optic nerve astrocytes
- (2013) Mallika Valapala et al. Nature Communications
- Activation of Notch in lgd mutant cells requires the fusion of late endosomes with the lysosome
- (2012) M. Schneider et al. JOURNAL OF CELL SCIENCE
- Autophagy Activation in Hepatocellular Carcinoma Contributes to the Tolerance of Oxaliplatin via Reactive Oxygen Species Modulation
- (2011) Z.-B. Ding et al. CLINICAL CANCER RESEARCH
- Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells
- (2010) Kazuhito Sasaki et al. BMC CANCER
- The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor
- (2010) T. Vaccari et al. DEVELOPMENT
- Rabconnectin-3 Is a Functional Regulator of Mammalian Notch Signaling
- (2010) Nilay Sethi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CD23 Sheddase A Disintegrin and Metalloproteinase 10 (ADAM10) Is Also Required for CD23 Sorting into B Cell-derived Exosomes
- (2010) Joel A. Mathews et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)
- (2009) D. I. Marks et al. BLOOD
- Metalloprotease ADAM10 Is Required for Notch1 Site 2 Cleavage
- (2009) Geert van Tetering et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
- (2009) Kasper M.A. Rouschop et al. JOURNAL OF CLINICAL INVESTIGATION
- Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
- (2009) Kasper M.A. Rouschop et al. RADIOTHERAPY AND ONCOLOGY
- Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis
- (2007) Kirsteen H. Maclean et al. JOURNAL OF CLINICAL INVESTIGATION
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started