BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

Neuronal activity alters BDNF–TrkB signaling kinetics and downstream functions

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proBDNF Negatively Regulates Neuronal Remodeling, Synaptic Transmission, and Synaptic Plasticity in Hippocampus

(2014) Jianmin Yang et al.   Cell Reports

Val66Met polymorphism of BDNF alters prodomain structure to induce neuronal growth cone retraction

(2013) Agustin Anastasia et al.   Nature Communications

BDNF and its pro-peptide are stored in presynaptic dense core vesicles in brain neurons

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The BDNF Val66Met Polymorphism Impairs NMDA Receptor-Dependent Synaptic Plasticity in the Hippocampus

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Plasma membrane insertion of the AMPA receptor GluA2 subunit is regulated by NSF binding and Q/R editing of the ion pore

(2010) Y. Araki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal release of proBDNF

(2009) Jianmin Yang et al.   NATURE NEUROSCIENCE

A critical role for PSD-95/AKAP interactions in endocytosis of synaptic AMPA receptors

(2009) Samarjit Bhattacharyya et al.   NATURE NEUROSCIENCE

Synaptic AMPA Receptor Plasticity and Behavior

(2009) Helmut W. Kessels et al.   NEURON

Mechanisms, locations, and kinetics of synaptic BDNF secretion: An update

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Multiple functions of precursor BDNF to CNS neurons: negative regulation of neurite growth, spine formation and cell survival

(2009) Hisatsugu Koshimizu et al.   Molecular Brain

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF

(2008) Tomoya Matsumoto et al.   NATURE NEUROSCIENCE

Understanding Synapses: Past, Present, and Future

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