Metaplasticity mechanisms restore plasticity and associativity in an animal model of Alzheimer’s disease

ZIP It: Neural Silencing Is an Additional Effect of the PKM-Zeta Inhibitor Zeta-Inhibitory Peptide

(2016) M. J. LeBlancq et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial dysfunction remodels one-carbon metabolism in human cells

(2016) Xiaoyan Robert Bao et al.   eLife

Zeta Inhibitory Peptide, a Candidate Inhibitor of Protein Kinase M , Is Excitotoxic to Cultured Hippocampal Neurons

(2015) N. Sadeh et al.   JOURNAL OF NEUROSCIENCE

Defective Age-Dependent Metaplasticity in a Mouse Model of Alzheimer's Disease

(2015) A. Megill et al.   JOURNAL OF NEUROSCIENCE

Ryanodine receptors

(2014) Mounia Chami et al.   Channels

PKCλ is critical in AMPA receptor phosphorylation and synaptic incorporation during LTP

(2013) Si-Qiang Ren et al.   EMBO JOURNAL

Prkcz null mice show normal learning and memory

(2013) Anna M. Lee et al.   NATURE

PKM-ζ is not required for hippocampal synaptic plasticity, learning and memory

(2013) Lenora J. Volk et al.   NATURE

Emerging roles of metaplasticity in behaviour and disease

(2013) Sarah R. Hulme et al.   TRENDS IN NEUROSCIENCES

Making Synapses Strong: Metaplasticity Prolongs Associativity of Long-Term Memory by Switching Synaptic Tag Mechanisms

(2012) Qin Li et al.   CEREBRAL CORTEX

Synaptic Distributions of GluA2 and PKM  in the Monkey Dentate Gyrus and Their Relationships with Aging and Memory

(2012) Y. Hara et al.   JOURNAL OF NEUROSCIENCE

Metaplasticity governs compartmentalization of synaptic tagging and capture through brain-derived neurotrophic factor (BDNF) and protein kinase M  (PKM )

(2011) S. Sajikumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation

(2011) T. Adasme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Making memories last: the synaptic tagging and capture hypothesis

(2010) Roger L. Redondo et al.   NATURE REVIEWS NEUROSCIENCE

Early neuronal dysfunction by amyloid β oligomers depends on activation of NR2B-containing NMDA receptors

(2010) Raik Rönicke et al.   NEUROBIOLOGY OF AGING

Dysregulation of the mTOR Pathway Mediates Impairment of Synaptic Plasticity in a Mouse Model of Alzheimer's Disease

(2010) Tao Ma et al.   PLoS One

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Metaplasticity: tuning synapses and networks for plasticity

(2008) Wickliffe C. Abraham   NATURE REVIEWS NEUROSCIENCE

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON