RANKL from bone marrow adipose lineage cells promotes osteoclast formation and bone loss

Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures

(2020) Yixuan Wang et al.   JOURNAL OF MEDICAL VIROLOGY

Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk

(2020) Lijun Wang et al.   Nature Communications

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

(2020) Leilei Zhong et al.   eLife

Macrophage-lineage TRAP+ cells recruit periosteum-derived cells for periosteal osteogenesis and regeneration

(2019) Bo Gao et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation

(2019) Sara G. Romeo et al.   NATURE CELL BIOLOGY

Clinical implications of bone marrow adiposity

(2018) A. G. Veldhuis-Vlug et al.   JOURNAL OF INTERNAL MEDICINE

Soluble RANKL contributes to osteoclast formation in adult mice but not ovariectomy-induced bone loss

(2018) Jinhu Xiong et al.   Nature Communications

A Matrine Derivative M54 Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss by Targeting Ribosomal Protein S5

(2018) Zhi Xin et al.   Frontiers in Pharmacology

18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways

(2018) Xiao Chen et al.   Frontiers in Pharmacology

PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ

(2018) Bo Yu et al.   Cell Stem Cell

Role of androgen receptor on cyclic mechanical stretch-regulated proliferation of C2C12 myoblasts and its upstream signals: IGF-1-mediated PI3K/Akt and MAPKs pathways

(2017) Yiming Ma et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF

(2017) Bo O. Zhou et al.   NATURE CELL BIOLOGY

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption

(2016) Jian Luo et al.   NATURE MEDICINE

PPAR-γ regulates pharmacological but not physiological or pathological osteoclast formation

(2016) Wei Zou et al.   NATURE MEDICINE

What's the matter with MAT? Marrow adipose tissue, metabolism, and skeletal health

(2014) Erica L. Scheller et al.   Annals of the New York Academy of Sciences

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow

(2014) Bo O. Zhou et al.   Cell Stem Cell

Comparison of circulating tumour necrosis factor superfamily cytokines in periodontitis patients undergoing supportive therapy: a case-controlled cross-sectional study comparing smokers and non-smokers in health and disease

(2013) Christopher J. Nile et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Osteoprotegerin, RANKL and bone turnover in postmenopausal osteoporosis

(2011) S. Jabbar et al.   JOURNAL OF CLINICAL PATHOLOGY

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

PGC1β Mediates PPARγ Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss

(2010) Wei Wei et al.   Cell Metabolism

Soluble receptor activator of nuclear factor-κB ligand (RANKL) and osteoprotegerin in ankylosing spondylitis: OPG is associated with poor physical mobility and reflects systemic inflammation

(2010) Chun-Hsiung Chen et al.   CLINICAL RHEUMATOLOGY

Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes

(2010) R. E. Aubert et al.   DIABETES OBESITY & METABOLISM

Cellular and Molecular Mechanisms of Bone Remodeling

(2010) Liza J. Raggatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of risedronate on bone marrow adipocytes in postmenopausal women

(2010) G. Duque et al.   OSTEOPOROSIS INTERNATIONAL

Rosiglitazone-Associated Fractures in Type 2 Diabetes: An analysis from A Diabetes Outcome Progression Trial (ADOPT)

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Role of platelet-derived growth factors in physiology and medicine

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