18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways
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Title
18β-Glycyrrhetinic Acid Inhibits Osteoclastogenesis In Vivo and In Vitro by Blocking RANKL-Mediated RANK–TRAF6 Interactions and NF-κB and MAPK Signaling Pathways
Authors
Keywords
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Journal
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-06-20
DOI
10.3389/fphar.2018.00647
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Note: Only part of the references are listed.- Structure-based development of an osteoprotegerin-like glycopeptide that blocks RANKL/RANK interactions and reduces ovariectomy-induced bone loss in mice
- (2018) Chao Liu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- (2018) Abhishek Chandra et al. FASEB JOURNAL
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- (2018) Zhi Xin et al. Frontiers in Pharmacology
- 18β-Glycyrrhetinic acid, the major bioactive component of Glycyrrhizae Radix, attenuates airway inflammation by modulating Th2 cytokines, GATA-3, STAT6, and Foxp3 transcription factors in an asthmatic mouse model
- (2017) Seung-Hyung Kim et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
- Enzyme replacement prevents neonatal death, liver damage, and osteoporosis in murine homocystinuria
- (2017) Tomas Majtan et al. FASEB JOURNAL
- Declining histone acetyltransferase GCN5 represses BMSC-mediated angiogenesis during osteoporosis
- (2017) Huan Jing et al. FASEB JOURNAL
- RANKL induces Bach1 nuclear import and attenuates Nrf2-mediated antioxidant enzymes, thereby augmenting intracellular reactive oxygen species signaling and osteoclastogenesis in mice
- (2017) Hiroyuki Kanzaki et al. FASEB JOURNAL
- Matrine prevents bone loss in ovariectomized mice by inhibiting RANKL-induced osteoclastogenesis
- (2017) Xiao Chen et al. FASEB JOURNAL
- Anti-inflammatory and hepatoprotective effects of glycyrrhetinic acid on CCl 4 -induced damage in precision-cut liver slices from Jian carp ( Cyprinus carpio var . jian) through inhibition of the nf-kƁ pathway
- (2017) Liping Cao et al. FISH & SHELLFISH IMMUNOLOGY
- Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice
- (2017) Genling Yang et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- 18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration
- (2017) Saisai Wang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Glycyrrhetinic acid-modified TPGS polymeric micelles for hepatocellular carcinoma-targeted therapy
- (2017) Xiumei Zhu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Addressing the Crisis in the Treatment of Osteoporosis: Better Paths Forward
- (2017) William V Stoecker et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Primary Osteoporosis Is Not Reflected by Disease-Specific DNA Methylation or Accelerated Epigenetic Age in Blood
- (2017) Eduardo Fernandez-Rebollo et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Prevalence of Osteoporosis and Low Bone Mass Among Puerto Rican Older Adults
- (2017) Sabrina E Noel et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Comparative Analysis of the Radiology of Osteoporotic Vertebral Fractures in Women and Men: Cross-Sectional and Longitudinal Observations from the Canadian Multicentre Osteoporosis Study (CaMos)
- (2017) Brian C Lentle et al. JOURNAL OF BONE AND MINERAL RESEARCH
- 18α-Glycyrrhetinic acid monoglucuronide as an anti-inflammatory agent through suppression of the NF-κB and MAPK signaling pathway
- (2017) Bo Li et al. MedChemComm
- Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis
- (2017) Xiao Chen et al. Cell Death & Disease
- Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway
- (2017) Mengrui Wu et al. Nature Communications
- The Optimal Duration of PTH(1–34) Infusion Is One Hour per Day to Increase Bone Mass in Rats
- (2016) Masaru Shimizu et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Prevalence of osteoporosis in China: a meta-analysis and systematic review
- (2016) Peng Chen et al. BMC PUBLIC HEALTH
- Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease
- (2016) Chang Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dedicated Perioperative Hip Fracture Comanagement Programs are Cost-effective in High-volume Centers: An Economic Analysis
- (2015) Eric Swart et al. CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
- Glycyrrhizic acid attenuates stem cell-like phenotypes of human dermal papilla cells
- (2015) Chayanin Kiratipaiboon et al. PHYTOMEDICINE
- Induction of osteoclast progenitors in inflammatory conditions: key to bone destruction in arthritis
- (2014) Alan Šućur et al. INTERNATIONAL ORTHOPAEDICS
- Delphinidin, One of the Major Anthocyanidins, Prevents Bone Loss through the Inhibition of Excessive Osteoclastogenesis in Osteoporosis Model Mice
- (2014) Sawako Moriwaki et al. PLoS One
- Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK signaling
- (2013) Fredrik Strålberg et al. FASEB JOURNAL
- Redundant miR-3077-5p and miR-705 mediate the shift of mesenchymal stem cell lineage commitment to adipocyte in osteoporosis bone marrow
- (2013) L Liao et al. Cell Death & Disease
- Adverse Reactions and Drug–Drug Interactions in the Management of Women with Postmenopausal Osteoporosis
- (2011) René Rizzoli et al. CALCIFIED TISSUE INTERNATIONAL
- Orai1-mediated calcium entry plays a critical role in osteoclast differentiation and function by regulating activation of the transcription factor NFATc1
- (2011) Sung-Yong Hwang et al. FASEB JOURNAL
- Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-κB and MAPK signaling pathways
- (2010) Chenghai Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Differential effects between the loss of MMP-2 and MMP-9 on structural and tissue-level properties of bone
- (2010) Jeffry S Nyman et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Diphenylhydantoin Inhibits Osteoclast Differentiation and Function Through Suppression of NFATc1 Signaling
- (2009) Masanori Koide et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Prevention of free fatty acid-induced hepatic lipotoxicity by 18β-glycyrrhetinic acid through lysosomal and mitochondrial pathways
- (2008) Xudong Wu et al. HEPATOLOGY
- RelA/p65 promotes osteoclast differentiation by blocking a RANKL-induced apoptotic JNK pathway in mice
- (2008) Sergio Vaira et al. JOURNAL OF CLINICAL INVESTIGATION
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