The glycine arginine‐rich domain of the RNA‐binding protein nucleolin regulates its subcellular localization

A Kinesin adapter directly mediates dendritic mRNA localization during neural development in mice

(2020) Hao Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of the RGG Domain and RNA Recognition Motif of Nucleolin in G-Quadruplex Stabilization

(2020) Tatsuki Masuzawa et al.   ACS Omega

Nucleolin Discriminates Drastically between Long-Loop and Short-Loop Quadruplexes

(2020) Abhijit Saha et al.   BIOCHEMISTRY

A reconstituted mammalian APC-kinesin complex selectively transports defined packages of axonal mRNAs

(2020) Sebastian Baumann et al.   Science Advances

FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences

(2020) Raeann Goering et al.   eLife

A Ca2+-Dependent Switch Activates Axonal Casein Kinase 2α Translation and Drives G3BP1 Granule Disassembly for Axon Regeneration

(2020) Pabitra K. Sahoo et al.   CURRENT BIOLOGY

RNA-recognition motifs and glycine and arginine-rich region cooperatively regulate the nucleolar localization of nucleolin

(2020) Mitsuru Okuwaki et al.   JOURNAL OF BIOCHEMISTRY

Importin α3 regulates chronic pain pathways in peripheral sensory neurons

(2020) Letizia Marvaldi et al.   SCIENCE

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

(2019) Jean-Michel Cioni et al.   CELL

Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation

(2019) Brian Tsang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell size sensing—a one-dimensional solution for a three-dimensional problem?

(2019) Ida Rishal et al.   BMC BIOLOGY

Nucleolin-based targeting strategies for cancer therapy: from targeted drug delivery to cytotoxic ligands

(2019) Sofia Romano et al.   DRUG DISCOVERY TODAY

The regulation, functions and clinical relevance of arginine methylation

(2019) Ernesto Guccione et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

(2019) Ya-Cheng Liao et al.   CELL

Arginine “Magic”: Guanidinium Like-Charge Ion Pairing from Aqueous Salts to Cell Penetrating Peptides

(2018) Mario Vazdar et al.   ACCOUNTS OF CHEMICAL RESEARCH

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation

(2018) Mario Hofweber et al.   CELL

RGG/RG Motif Regions in RNA Binding and Phase Separation

(2018) P. Andrew Chong et al.   JOURNAL OF MOLECULAR BIOLOGY

G-quadruplex binding ability of TLS/FUS depends on the β-spiral structure of the RGG domain

(2018) Ryota Yagi et al.   NUCLEIC ACIDS RESEARCH

Locally translated mTOR controls axonal local translation in nerve injury

(2018) Marco Terenzio et al.   SCIENCE

Citrullination of RGG Motifs in FET Proteins by PAD4 Regulates Protein Aggregation and ALS Susceptibility

(2018) Chizu Tanikawa et al.   Cell Reports

Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration

(2018) Pabitra K. Sahoo et al.   Nature Communications

Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

(2018) Noga Gershoni-Emek et al.   Frontiers in Molecular Neuroscience

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Arginine-rich cell-penetrating peptides induce membrane multilamellarity and subsequently enter via formation of a fusion pore

(2018) Christoph Allolio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-efficiency optogenetic silencing with soma-targeted anion-conducting channelrhodopsins

(2018) Mathias Mahn et al.   Nature Communications

Genetic mutations in RNA-binding proteins and their roles in ALS

(2017) Katannya Kapeli et al.   HUMAN GENETICS

Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems

(2017) Ken Y Chan et al.   NATURE NEUROSCIENCE

Nucleolin Targeting Impairs the Progression of Pancreatic Cancer and Promotes the Normalization of Tumor Vasculature

(2016) Maud-Emmanuelle Gilles et al.   CANCER RESEARCH

Current Understanding of Direct Translocation of Arginine-Rich Cell-Penetrating Peptides and Its Internalization Mechanisms

(2016) Toshihide Takeuchi et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size

(2016) Rotem Ben-Tov Perry et al.   Cell Reports

The roles of nucleolin subcellular localization in cancer

(2015) Caroline Madeleine Berger et al.   BIOCHIMIE

Spatiotemporal control of phosphatidylinositol 4-phosphate by Sac2 regulates endocytic recycling

(2015) FoSheng Hsu et al.   JOURNAL OF CELL BIOLOGY

Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord Injury

(2015) Y. Zou et al.   JOURNAL OF NEUROSCIENCE

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP

(2015) Nikita Vasilyev et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CHARMM-GUIMembrane Buildertoward realistic biological membrane simulations

(2014) Emilia L. Wu et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Translocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins

(2014) Janely Pae et al.   JOURNAL OF CONTROLLED RELEASE

Fundamental Molecular Mechanism for the Cellular Uptake of Guanidinium-Rich Molecules

(2014) Henry D. Herce et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of arginine-rich cell penetrating peptides on membrane pore formation and life-times: a molecular simulation study

(2014) Delin Sun et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

SAINTexpress: Improvements and additional features in Significance Analysis of INTeractome software

(2013) Guoci Teo et al.   Journal of Proteomics

Defining the RGG/RG Motif

(2013) Palaniraja Thandapani et al.   MOLECULAR CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Cell length sensing for neuronal growth control

(2013) Christin A. Albus et al.   TRENDS IN CELL BIOLOGY

A Motor-Driven Mechanism for Cell-Length Sensing

(2012) Ida Rishal et al.   Cell Reports

Oncogenic Synergism between ErbB1, Nucleolin, and Mutant Ras

(2011) K. Farin et al.   CANCER RESEARCH

A Data Processing Pipeline for Mammalian Proteome Dynamics Studies Using Stable Isotope Metabolic Labeling

(2011) Shenheng Guan et al.   MOLECULAR & CELLULAR PROTEOMICS

Accounting for electronic polarization in non-polarizable force fields

(2011) Igor Leontyev et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Translocation of HIV TAT peptide and analogues induced by multiplexed membrane and cytoskeletal interactions

(2011) A. Mishra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types

(2010) Jeffery B. Klauda et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Rank–rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures

(2010) Seema B. Plaisier et al.   NUCLEIC ACIDS RESEARCH

Inpp5f Is a Polyphosphoinositide Phosphatase That Regulates Cardiac Hypertrophic Responsiveness

(2009) Wenting Zhu et al.   CIRCULATION RESEARCH

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Conditional knockout of nucleolin in DT40 cells reveals the functional redundancy of its RNA-binding domains

(2008) Sébastien Storck et al.   BIOLOGY OF THE CELL