Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP

Fragile X syndrome due to a missense mutation

(2014) Leila K Myrick et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Human FMRP contains an integral tandem Agenet (Tudor) and KH motif in the amino terminal domain

(2014) Leila K. Myrick et al.   HUMAN MOLECULAR GENETICS

Analysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequences

(2014) Joshua A. Suhl et al.   HUMAN MOLECULAR GENETICS

Fragile X Mental Retardation Protein Regulates Translation by Binding Directly to the Ribosome

(2014) Eileen Chen et al.   MOLECULAR CELL

C9orf72 nucleotide repeat structures initiate molecular cascades of disease

(2014) Aaron R. Haeusler et al.   NATURE

A G-quadruplex–containing RNA activates fluorescence in a GFP-like fluorophore

(2014) Hao Huang et al.   Nature Chemical Biology

Structural basis for activity of highly efficient RNA mimics of green fluorescent protein

(2014) Katherine Deigan Warner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Subcellular Fractionation and Localization Studies Reveal a Direct Interaction of the Fragile X Mental Retardation Protein (FMRP) with Nucleolin

(2014) Mohamed S. Taha et al.   PLoS One

Defining the RGG/RG Motif

(2013) Palaniraja Thandapani et al.   MOLECULAR CELL

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

RGG motif proteins: Modulators of mRNA functional states

(2012) Purusharth Rajyaguru et al.   CELL CYCLE

The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts

(2012) Alexander G. Baltz et al.   MOLECULAR CELL

FMRP targets distinct mRNA sequence elements to regulate protein expression

(2012) Manuel Ascano et al.   NATURE

G-quadruplexes in RNA biology

(2012) Stefania Millevoi et al.   Wiley Interdisciplinary Reviews-RNA

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

G–quadruplex RNA structure as a signal for neurite mRNA targeting

(2011) Murugan Subramanian et al.   EMBO REPORTS

Identification of Ewing’s sarcoma protein as a G-quadruplex DNA- and RNA-binding protein

(2011) Kentaro Takahama et al.   FEBS Journal

A new regulatory function of the region proximal to the RGG box in the Fragile X mental retardation protein

(2011) E. Blackwell et al.   JOURNAL OF CELL SCIENCE

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction

(2011) Anh Tuân Phan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Which Comes First in Fragile X Syndrome, Dendritic Spine Dysgenesis or Defects in Circuit Plasticity?

(2011) Carlos Portera-Cailliau   NEUROSCIENTIST

Differential radial capillary action of ligand assay for high-throughput detection of protein-metabolite interactions

(2011) K. G. Roelofs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FMR1 and the Continuum of Primary Ovarian Insufficiency

(2011) Shannon Sullivan et al.   SEMINARS IN REPRODUCTIVE MEDICINE

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Identification of novel FMR1 variants by massively parallel sequencing in developmentally delayed males

(2010) Stephen C. Collins et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P

(2010) R. L. Coffee et al.   Disease Models & Mechanisms

Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA

(2010) E. Blackwell et al.   HUMAN MOLECULAR GENETICS

Fragile X Mental Retardation Protein Is Required for Synapse Elimination by the Activity-Dependent Transcription Factor MEF2

(2010) Brad E. Pfeiffer et al.   NEURON

Autism spectrum disorder in fragile X syndrome: A longitudinal evaluation

(2009) R. Nick Hernandez et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs

(2009) J. C. Darnell et al.   HUMAN MOLECULAR GENETICS

Role for G-Quadruplex RNA Binding by Epstein-Barr Virus Nuclear Antigen 1 in DNA Replication and Metaphase Chromosome Attachment

(2009) J. Norseen et al.   JOURNAL OF VIROLOGY

Fragile X mental retardation protein recognition of G quadruplex structure per se is sufficient for high affinity binding to RNA

(2008) Medhavi Bole et al.   Molecular BioSystems

Fragile X Syndrome: Loss of Local mRNA Regulation Alters Synaptic Development and Function

(2008) Gary J. Bassell et al.   NEURON

Fragile X mental retardation protein interactions with the microtubule associated protein 1B RNA

(2008) L. Menon et al.   RNA