Plant homeodomain fingers form a helping hand for transcription

Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4

(2010) Chengyang Huang et al.   CELL RESEARCH

Structural insights into a novel histone demethylase PHF8

(2010) Lin Yu et al.   CELL RESEARCH

Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans

(2010) Hanqing Lin et al.   CELL RESEARCH

Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans

(2010) Ying Yang et al.   CELL RESEARCH

The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation

(2010) Jihui Qiu et al.   CELL RESEARCH

PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis

(2010) Ziqi Zhu et al.   CELL RESEARCH

Crystal structure of the PHF8 Jumonji domain, anNε-methyl lysine demethylase

(2010) Wyatt W. Yue et al.   FEBS LETTERS

KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development

(2010) Y.-i. Tsukada et al.   GENES & DEVELOPMENT

Recognition of Histone H3K4 Trimethylation by the Plant Homeodomain of PHF2 Modulates Histone Demethylation

(2010) Hong Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PHF8 Targets Histone Methylation and RNA Polymerase II To Activate Transcription

(2010) K. Fortschegger et al.   MOLECULAR AND CELLULAR BIOLOGY

A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation

(2010) Daniela Kleine-Kohlbrecher et al.   MOLECULAR CELL

PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression

(2010) Wen Liu et al.   NATURE

Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development

(2010) Hank H. Qi et al.   NATURE

PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation

(2010) Weijun Feng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Autism-associated familial microdeletion of Xp11.22

(2009) Y Qiao et al.   CLINICAL GENETICS

AIRE activated tissue specific genes have histone modifications associated with inactive chromatin

(2009) Tõnis Org et al.   HUMAN MOLECULAR GENETICS

PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase

(2009) Christoph Loenarz et al.   HUMAN MOLECULAR GENETICS

Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

(2009) John R Horton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Crosstalk among Histone Modifications

(2008) Tamaki Suganuma et al.   CELL

Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters

(2008) Leighton J. Core et al.   SCIENCE