Homeostasis of the Gram-negative cell envelope

The assembly of β-barrel outer membrane proteins

(2021) David Tomasek et al.   CURRENT OPINION IN MICROBIOLOGY

Complex Response of the CpxAR Two-Component System to β-Lactams on Antibiotic Resistance and Envelope Homeostasis in Enterobacteriaceae

(2020) Muriel Masi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide

(2020) Randi L. Guest et al.   mBio

An Essential Membrane Protein Modulates the Proteolysis of LpxC to Control Lipopolysaccharide Synthesis in Escherichia coli

(2020) Elayne M. Fivenson et al.   mBio

Lipoprotein Lpp regulates the mechanical properties of the E. coli cell envelope

(2020) Marion Mathelié-Guinlet et al.   Nature Communications

Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria

(2020) Jim E. Horne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the essential inner membrane lipopolysaccharide–PbgA complex

(2020) Thomas Clairfeuille et al.   NATURE

Structural insight into the formation of lipoprotein-β-barrel complexes

(2020) Raquel Rodríguez-Alonso et al.   Nature Chemical Biology

IgaA negatively regulates the Rcs Phosphorelay via contact with the RcsD Phosphotransfer Protein

(2020) Erin A. Wall et al.   PLoS Genetics

Border Control: Regulating LPS Biogenesis

(2020) Randi L. Guest et al.   TRENDS IN MICROBIOLOGY

Bacterial Cell Wall Quality Control during Environmental Stress

(2020) Elizabeth A. Mueller et al.   mBio

Rcs Phosphorelay Responses to Truncated Lipopolysaccharide-Induced Cell Envelope Stress in Yersinia enterocolitica

(2020) Jiao Meng et al.   MOLECULES

Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect

(2019) Niccolò Morè et al.   mBio

Fine tuning of σE activation suppresses multiple assembly-defective mutations in Escherichia coli

(2019) Elizabeth M. Hart et al.   JOURNAL OF BACTERIOLOGY

The lipoprotein NlpE is a Cpx sensor that serves as a sentinel for protein sorting and folding defects in the Escherichia coli envelope

(2019) Antoine Delhaye et al.   JOURNAL OF BACTERIOLOGY

Chemical Validation of DegS As a Target for the Development of Antibiotics with a Novel Mode of Action

(2019) Jens Bongard et al.   ChemMedChem

A Stress Response Monitoring Lipoprotein Trafficking to the Outer Membrane

(2019) Kerrie L. May et al.   mBio

Improper Coordination of BamA and BamD Results in Bam Complex Jamming by a Lipoprotein Substrate

(2019) Muralidhar Tata et al.   mBio

Envelope stress responses: balancing damage repair and toxicity

(2019) Angela M. Mitchell et al.   NATURE REVIEWS MICROBIOLOGY

A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier

(2019) Elizabeth M. Hart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibitor of intramembrane protease RseP blocks the σEresponse causing lethal accumulation of unfolded outer membrane proteins

(2018) Anna Konovalova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The outer membrane is an essential load-bearing element in Gram-negative bacteria

(2018) Enrique R. Rojas et al.   NATURE

Redefining the essential trafficking pathway for outer membrane lipoproteins

(2017) Marcin Grabowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Rcs-Regulated Colanic Acid Capsule Maintains Membrane Potential in Salmonella enterica serovar Typhimurium

(2017) Jasmine M. Pando et al.   mBio

The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli

(2017) Ghee Chuan Lai et al.   PLoS Genetics

A Suppressor Mutation That Creates a Faster and More Robust σE Envelope Stress Response

(2016) Anna Konovalova et al.   JOURNAL OF BACTERIOLOGY

Crosstalk between the lipopolysaccharide and phospholipid pathways during outer membrane biogenesis inEscherichia coli

(2016) Akintunde Emiola et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fine-Tuning of the Cpx Envelope Stress Response Is Required for Cell Wall Homeostasis in Escherichia coli

(2016) Antoine Delhaye et al.   mBio

The CpxQ sRNA Negatively Regulates Skp To Prevent Mistargeting of β-Barrel Outer Membrane Proteins into the Cytoplasmic Membrane

(2016) Marcin Grabowicz et al.   mBio

Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli

(2016) Jean-Emmanuel Hugonnet et al.   eLife

A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane

(2016) Anna Konovalova et al.   eLife

Beta-Lactam Antibiotics Induce a Lethal Malfunctioning of the Bacterial Cell Wall Synthesis Machinery

(2014) Hongbaek Cho et al.   CELL

Detecting Envelope Stress by Monitoring β-Barrel Assembly

(2014) Seung-Hyun Cho et al.   CELL

MicL, a new  E-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein

(2014) M. S. Guo et al.   GENES & DEVELOPMENT

The Cpx Envelope Stress Response Modifies Peptidoglycan Cross-Linking via the l,d-Transpeptidase LdtD and the Novel Protein YgaU

(2014) Margarita Bernal-Cabas et al.   JOURNAL OF BACTERIOLOGY

Transmembrane domain of surface-exposed outer membrane lipoprotein RcsF is threaded through the lumen of  -barrel proteins

(2014) A. Konovalova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eliminating a Set of Four Penicillin Binding Proteins Triggers the Rcs Phosphorelay and Cpx Stress Responses in Escherichia coli

(2013) K. L. Evans et al.   JOURNAL OF BACTERIOLOGY

The Rcs Stress Response and Accessory Envelope Proteins Are Required for De Novo Generation of Cell Shape in Escherichia coli

(2013) D. K. Ranjit et al.   JOURNAL OF BACTERIOLOGY

Dual Molecular Signals Mediate the Bacterial Response to Outer-Membrane Stress

(2013) S. Lima et al.   SCIENCE

The Spanin Complex Is Essential for Lambda Lysis

(2012) J. Berry et al.   JOURNAL OF BACTERIOLOGY

Defective Lipoprotein Sorting Induces lolA Expression through the Rcs Stress Response Phosphorelay System

(2012) K. Tao et al.   JOURNAL OF BACTERIOLOGY

Exploring the relationship between lipoprotein mislocalization and activation of the Rcs signal transduction system in Escherichia coli

(2012) Y. Shiba et al.   MICROBIOLOGY-SGM

Analysis of the Networks Controlling the Antimicrobial-Peptide-Dependent Induction of Klebsiella pneumoniae Virulence Factors

(2011) Enrique Llobet et al.   INFECTION AND IMMUNITY

Genetic Interaction Maps in Escherichia coli Reveal Functional Crosstalk among Cell Envelope Biogenesis Pathways

(2011) Mohan Babu et al.   PLoS Genetics

Antimicrobial Peptides Activate the Rcs Regulon through the Outer Membrane Lipoprotein RcsF

(2010) C. Farris et al.   JOURNAL OF BACTERIOLOGY

The Rcs Two-Component System Regulates Expression of Lysozyme Inhibitors and Is Induced by Exposure to Lysozyme

(2009) L. Callewaert et al.   JOURNAL OF BACTERIOLOGY

Characterization of the Cpx Regulon in Escherichia coli Strain MC4100

(2008) N. L. Price et al.   JOURNAL OF BACTERIOLOGY

The Rcs Phosphorelay Is a Cell Envelope Stress Response Activated by Peptidoglycan Stress and Contributes to Intrinsic Antibiotic Resistance

(2008) M. E. Laubacher et al.   JOURNAL OF BACTERIOLOGY

Structural biology of membrane-intrinsic β-barrel enzymes: Sentinels of the bacterial outer membrane

(2007) Russell E. Bishop   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES