The assembly of β-barrel outer membrane proteins

Structure of a nascent membrane protein as it folds on the BAM complex

(2020) David Tomasek et al.   NATURE

Structural insight into the formation of lipoprotein-β-barrel complexes

(2020) Raquel Rodríguez-Alonso et al.   Nature Chemical Biology

The gain-of-function allelebamAE470Kbypasses the essential requirement for BamD in β-barrel outer membrane protein assembly

(2020) Elizabeth M. Hart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insight into mitochondrial β-barrel outer membrane protein biogenesis

(2020) Kathryn A. Diederichs et al.   Nature Communications

Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA

(2020) Elizabeth M. Hart et al.   JOURNAL OF BACTERIOLOGY

Bacterial outer membrane proteins assemble via asymmetric interactions with the BamA β-barrel

(2019) Matthew T. Doyle et al.   Nature Communications

Chimeric peptidomimetic antibiotics against Gram-negative bacteria

(2019) Anatol Luther et al.   NATURE

A new antibiotic selectively kills Gram-negative pathogens

(2019) Yu Imai et al.   NATURE

A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier

(2019) Elizabeth M. Hart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA

(2019) James Lee et al.   eLife

Monoclonal antibody targeting the β-barrel assembly machine ofEscherichia coliis bactericidal

(2018) Kelly M. Storek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion

(2018) James Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane protein insertion through a mitochondrial β-barrel gate

(2018) Alexandra I. C. Höhr et al.   SCIENCE

The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane

(2018) Sachith D. Gunasinghe et al.   Cell Reports

Conformational Changes That Coordinate the Activity of BamA and BamD Allowing β-Barrel Assembly

(2017) Anne L. McCabe et al.   JOURNAL OF BACTERIOLOGY

The TPR domain of BepA is required for productive interaction with substrate proteins and the β-barrel assembly machinery complex

(2017) Yasushi Daimon et al.   MOLECULAR MICROBIOLOGY

Job contenders: roles of the β-barrel assembly machinery and the translocation and assembly module in autotransporter secretion

(2017) Cécile Albenne et al.   MOLECULAR MICROBIOLOGY

Membrane integration of an essential β-barrel protein prerequires burial of an extracellular loop

(2017) Joseph S. Wzorek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folding of a bacterial integral outer membrane protein is initiated in the periplasm

(2017) Rakesh Sikdar et al.   Nature Communications

A Supercomplex Spanning the Inner and Outer Membranes Mediates the Biogenesis of β-Barrel Outer Membrane Proteins in Bacteria

(2016) Yan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis of outer membrane protein insertion by the BAM complex

(2016) Yinghong Gu et al.   NATURE

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins

(2016) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Characterization of a stalled complex on the β-barrel assembly machine

(2016) James Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of the  -barrel assembly machinery complex

(2016) J. Bakelar et al.   SCIENCE

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

(2016) Matthew G. Iadanza et al.   Nature Communications

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins

(2016) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane

(2016) Anna Konovalova et al.   eLife

BamA Alone Accelerates Outer Membrane Protein Folding In Vitro through a Catalytic Mechanism

(2015) Ashlee M. Plummer et al.   BIOCHEMISTRY

Inhibition of the β-barrel assembly machine by a peptide that binds BamD

(2015) Christine L. Hagan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detecting Envelope Stress by Monitoring β-Barrel Assembly

(2014) Seung-Hyun Cho et al.   CELL

Structural and functional analysis of the β-barrel domain of BamA from Escherichia coli

(2014) Dongchun Ni et al.   FASEB JOURNAL

Lateral Opening and Exit Pore Formation Are Required for BamA Function

(2014) Nicholas Noinaj et al.   STRUCTURE

Structure of BamA, an essential factor in outer membrane protein biogenesis

(2014) Reinhard Albrecht et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural insight into the biogenesis of β-barrel membrane proteins

(2013) Nicholas Noinaj et al.   NATURE

Activation of the Escherichia coli  -barrel assembly machine (Bam) is required for essential components to interact properly with substrate

(2012) D. P. Ricci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disulfide Rearrangement Triggered by Translocon Assembly Controls Lipopolysaccharide Export

(2012) S.-S. Chng et al.   SCIENCE

The ReconstitutedEscherichia coliBam Complex Catalyzes Multiple Rounds of β-Barrel Assembly

(2011) Christine L. Hagan et al.   BIOCHEMISTRY

BamE Modulates the Escherichia coli Beta-Barrel Assembly Machine Component BamA

(2011) N. W. Rigel et al.   JOURNAL OF BACTERIOLOGY

The complex that inserts lipopolysaccharide into the bacterial outer membrane forms a two-protein plug-and-barrel

(2011) E. Freinkman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential and spatially restricted interactions of assembly factors with an autotransporter   domain

(2011) R. Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstitution of Outer Membrane Protein Assembly from Purified Components

(2010) C. L. Hagan et al.   SCIENCE