Bacterial Cell Wall Quality Control during Environmental Stress

Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi‐enzyme complexes in Escherichia coli

(2020) Manuel Banzhaf et al.   EMBO JOURNAL

Uncovering the activities, biological roles, and regulation of bacterial cell wall hydrolases and tailoring enzymes

(2020) Truc Do et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peptidoglycan Hydrolases RipA and Ami1 Are Critical for Replication and Persistence of Mycobacterium tuberculosis in the Host

(2020) Claire Healy et al.   mBio

Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects

(2020) Antoine Vigouroux et al.   eLife

The transpeptidase PBP2 governs initial localization and activity of the major cell-wall synthesis machinery in E. coli

(2020) Gizem Özbaykal et al.   eLife

Regulation of peptidoglycan synthesis and remodelling

(2020) Alexander J. F. Egan et al.   NATURE REVIEWS MICROBIOLOGY

pH-dependent activation of cytokinesis modulates Escherichia coli cell size

(2020) Elizabeth A. Mueller et al.   PLoS Genetics

Global phenotypic profiling identifies a conserved actinobacterial cofactor for a bifunctional PBP-type cell wall synthase

(2020) Joel W Sher et al.   eLife

An alternative penicillin-binding protein involved in Salmonella relapses following ceftriaxone therapy

(2020) Sónia Castanheira et al.   EBioMedicine

Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa

(2020) Nathanael A. Caveney et al.   STRUCTURE

FtsW is a peptidoglycan polymerase that is functional only in complex with its cognate penicillin-binding protein

(2019) Atsushi Taguchi et al.   Nature Microbiology

An Acinetobacter baumannii, Zinc-Regulated Peptidase Maintains Cell Wall Integrity during Immune-Mediated Nutrient Sequestration

(2019) Zachery R. Lonergan et al.   Cell Reports

Endopeptidase Regulation as a Novel Function of the Zur-Dependent Zinc Starvation Response

(2019) Shannon G. Murphy et al.   mBio

Peptidoglycan Remodeling Enables Escherichia coli To Survive Severe Outer Membrane Assembly Defect

(2019) Niccolò Morè et al.   mBio

Movement dynamics of divisome proteins and PBP2x:FtsW in cells of Streptococcus pneumoniae

(2019) Amilcar J. Perez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of the DedD Protein in Escherichia coli Cell Constriction

(2019) Bing Liu et al.   JOURNAL OF BACTERIOLOGY

Plasticity of Escherichia coli cell wall metabolism promotes fitness and antibiotic resistance across environmental conditions

(2019) Elizabeth A Mueller et al.   eLife

Bacillus subtilis cell diameter is determined by the opposing actions of two distinct cell wall synthetic systems

(2019) Michael F. Dion et al.   Nature Microbiology

Lytic transglycosylases RlpA and MltC assist in Vibrio cholerae daughter cell separation

(2019) Anna I. Weaver et al.   MOLECULAR MICROBIOLOGY

Cell Wall Deficiency as a Coping Strategy for Stress

(2019) Dennis Claessen et al.   TRENDS IN MICROBIOLOGY

Cell Shape and Antibiotic Resistance Are Maintained by the Activity of Multiple FtsW and RodA Enzymes in Listeria monocytogenes

(2019) Jeanine Rismondo et al.   mBio

Persistent Mycobacterium tuberculosis infection in mice requires PerM for successful cell division

(2019) Ruojun Wang et al.   eLife

Conserved mechanism of cell-wall synthase regulation revealed by the identification of a new PBP activator inPseudomonas aeruginosa

(2018) Neil G. Greene et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of divisome assembly rescued by FtsN–FtsA interaction inEscherichia coli

(2018) Sebastien Pichoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular imaging of glycan chains couples cell-wall polysaccharide architecture to bacterial cell morphology

(2018) Robert D. Turner et al.   Nature Communications

Induced conformational changes activate the peptidoglycan synthase PBP1B

(2018) Alexander J. F. Egan et al.   MOLECULAR MICROBIOLOGY

Bacterial Strategies to Preserve Cell Wall Integrity Against Environmental Threats

(2018) Akhilesh K. Yadav et al.   Frontiers in Microbiology

A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery

(2018) Patricia D. A. Rohs et al.   PLoS Genetics

Tat-exported peptidoglycan amidase-dependent cell division contributes to Salmonella Typhimurium fitness in the inflamed gut

(2018) Mayuka Fujimoto et al.   PLoS Pathogens

High Osmolarity Modulates Bacterial Cell Size through Reducing Initiation Volume in Escherichia coli

(2018) Xiongfeng Dai et al.   mSphere

PBP1B Glycosyltransferase and Transpeptidase Activities Play Different Essential Roles during the De Novo Regeneration of Rod Morphology in Escherichia coli

(2017) Dev K. Ranjit et al.   JOURNAL OF BACTERIOLOGY

Functional redundancy of division specific penicillin-binding proteins in Bacillus subtilis

(2017) Jad Sassine et al.   MOLECULAR MICROBIOLOGY

Assembly and activation of the Escherichia coli divisome

(2017) Shishen Du et al.   MOLECULAR MICROBIOLOGY

GTPase activity–coupled treadmilling of the bacterial tubulin FtsZ organizes septal cell wall synthesis

(2017) Xinxing Yang et al.   SCIENCE

Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division

(2017) Alexandre W. Bisson-Filho et al.   SCIENCE

A Specialized Peptidoglycan Synthase Promotes Salmonella Cell Division inside Host Cells

(2017) Sónia Castanheira et al.   mBio

Non-canonical activation of OmpR drives acid and osmotic stress responses in single bacterial cells

(2017) Smarajit Chakraborty et al.   Nature Communications

The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli

(2017) Ghee Chuan Lai et al.   PLoS Genetics

SEDS proteins are a widespread family of bacterial cell wall polymerases

(2016) Alexander J. Meeske et al.   NATURE

Splitsville: structural and functional insights into the dynamic bacterial Z ring

(2016) Daniel P. Haeusser et al.   NATURE REVIEWS MICROBIOLOGY

Cofactor bypass variants reveal a conformational control mechanism governing cell wall polymerase activity

(2016) Monica Markovski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FtsEX acts on FtsA to regulate divisome assembly and activity

(2016) Shishen Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Redundancy of Peptidoglycan Carboxypeptidases Ensures Robust Cell Shape Maintenance in Escherichia coli

(2016) Katharina Peters et al.   mBio

Single-molecule imaging reveals modulation of cell wall synthesis dynamics in live bacterial cells

(2016) Timothy K. Lee et al.   Nature Communications

Mechanical Genomics Identifies Diverse Modulators of Bacterial Cell Stiffness

(2016) George K. Auer et al.   Cell Systems

Bacterial cell wall biogenesis is mediated by SEDS and PBP polymerase families functioning semi-autonomously

(2016) Hongbaek Cho et al.   Nature Microbiology

Identification of MltG as a potential terminase for peptidoglycan polymerization in bacteria

(2015) Rachel Yunck et al.   MOLECULAR MICROBIOLOGY

A novel peptidoglycan D,L-endopeptidase induced bySalmonellainside eukaryotic cells contributes to virulence

(2015) Gadea Rico-Pérez et al.   MOLECULAR MICROBIOLOGY

A role for the FtsQLB complex in cytokinetic ring activation revealed by anftsLallele that accelerates division

(2015) Mary-Jane Tsang et al.   MOLECULAR MICROBIOLOGY

Roles for both FtsA and the FtsBLQ subcomplex in FtsN-stimulated cell constriction inEscherichia coli

(2015) Bing Liu et al.   MOLECULAR MICROBIOLOGY

MreC and MreD Proteins Are Not Required for Growth of Staphylococcus aureus

(2015) Andreia C. Tavares et al.   PLoS One

MurJ and a novel lipid II flippase are required for cell wall biogenesis inBacillus subtilis

(2015) Alexander J. Meeske et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disruption of an M. tuberculosis Membrane Protein Causes a Magnesium-dependent Cell Division Defect and Failure to Persist in Mice

(2015) Nichole Goodsmith et al.   PLoS Pathogens

Staphylococcus aureus Survives with a Minimal Peptidoglycan Synthesis Machine but Sacrifices Virulence and Antibiotic Resistance

(2015) Patricia Reed et al.   PLoS Pathogens

The stoichiometric divisome: a hypothesis

(2015) Alexander J. F. Egan et al.   Frontiers in Microbiology

Differential Requirement for PBP1a and PBP1b inIn VivoandIn VitroFitness of Vibrio cholerae

(2014) Tobias Dörr et al.   INFECTION AND IMMUNITY

Cell Separation in Vibrio cholerae Is Mediated by a Single Amidase Whose Action Is Modulated by Two Nonredundant Activators

(2014) A. Moll et al.   JOURNAL OF BACTERIOLOGY

Structural Insights into the Lipoprotein Outer Membrane Regulator of Penicillin-binding Protein 1B

(2014) Dustin T. King et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissecting Escherichia coli Outer Membrane Biogenesis Using Differential Proteomics

(2014) Alessandra M. Martorana et al.   PLoS One

Outer-membrane lipoprotein LpoB spans the periplasm to stimulate the peptidoglycan synthase PBP1B

(2014) A. J. F. Egan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

(2014) L.-T. Sham et al.   SCIENCE

Elongated Structure of the Outer-Membrane Activator of Peptidoglycan Synthesis LpoA: Implications for PBP1A Stimulation

(2014) Nicolas L. Jean et al.   STRUCTURE

Genes Contributing to Staphylococcus aureus Fitness in Abscess- and Infection-Related Ecologies

(2014) M. D. Valentino et al.   mBio

A Genome-Wide Screen for Bacterial Envelope Biogenesis Mutants Identifies a Novel Factor Involved in Cell Wall Precursor Metabolism

(2014) Catherine Paradis-Bleau et al.   PLoS Genetics

Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth ofVibrio cholerae

(2013) Tobias Dörr et al.   MOLECULAR MICROBIOLOGY

Osmolality-Dependent Relocation of Penicillin-Binding Protein PBP2 to the Division Site in Caulobacter crescentus

(2012) J. Hocking et al.   JOURNAL OF BACTERIOLOGY

Three redundant murein endopeptidases catalyse an essential cleavage step in peptidoglycan synthesis ofEscherichia coliK12

(2012) Santosh Kumar Singh et al.   MOLECULAR MICROBIOLOGY

The Requirement for Pneumococcal MreC and MreD Is Relieved by Inactivation of the Gene Encoding PBP1a

(2011) A. D. Land et al.   JOURNAL OF BACTERIOLOGY

The YvcK protein is required for morphogenesis via localization of PBP1 under gluconeogenic growth conditions in Bacillus subtilis

(2011) Elodie Foulquier et al.   MOLECULAR MICROBIOLOGY

From the regulation of peptidoglycan synthesis to bacterial growth and morphology

(2011) Athanasios Typas et al.   NATURE REVIEWS MICROBIOLOGY

The bacterial actin MreB rotates, and rotation depends on cell-wall assembly

(2011) S. van Teeffelen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Processive Movement of MreB-Associated Cell Wall Biosynthetic Complexes in Bacteria

(2011) J. Dominguez-Escobar et al.   SCIENCE

Coupled, Circumferential Motions of the Cell Wall Synthesis Machinery and MreB Filaments in B. subtilis

(2011) E. C. Garner et al.   SCIENCE

Bacterial Osmoregulation: A Paradigm for the Study of Cellular Homeostasis

(2010) Janet M. Wood   Annual Review of Microbiology

Lipoprotein Cofactors Located in the Outer Membrane Activate Bacterial Cell Wall Polymerases

(2010) Catherine Paradis-Bleau et al.   CELL

Regulation of Peptidoglycan Synthesis by Outer-Membrane Proteins

(2010) Athanasios Typas et al.   CELL

Phenotypic Landscape of a Bacterial Cell

(2010) Robert J. Nichols et al.   CELL

A Role for the Class A Penicillin-Binding Protein PonA2 in the Survival of Mycobacterium smegmatis under Conditions of Nonreplication

(2010) M.-M. Patru et al.   JOURNAL OF BACTERIOLOGY

The Mycobacterium tuberculosis protein LdtMt2 is a nonclassical transpeptidase required for virulence and resistance to amoxicillin

(2010) Radhika Gupta et al.   NATURE MEDICINE

Novel Role of Phosphorylation-Dependent Interaction between FtsZ and FipA in Mycobacterial Cell Division

(2010) Kamakshi Sureka et al.   PLoS One

Architecture of peptidoglycan: more data and more models

(2010) Waldemar Vollmer et al.   TRENDS IN MICROBIOLOGY

Mycobacterial survival strategies in the phagosome: defence against host stresses

(2009) Sabine Ehrt et al.   CELLULAR MICROBIOLOGY

Role of Class A Penicillin-Binding Proteins in the Expression of  -Lactam Resistance in Enterococcus faecium

(2009) L. B. Rice et al.   JOURNAL OF BACTERIOLOGY

ATP-Binding Site Lesions in FtsE Impair Cell Division

(2009) S. J. R. Arends et al.   JOURNAL OF BACTERIOLOGY

Acid-Susceptible Mutants of Mycobacterium tuberculosis Share Hypersusceptibility to Cell Wall and Oxidative Stress and to the Host Environment

(2008) O. H. Vandal et al.   JOURNAL OF BACTERIOLOGY

α-Macroglobulins Are Present in Some Gram-negative Bacteria

(2008) Ninh Doan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How Bacteria Consume Their Own Exoskeletons (Turnover and Recycling of Cell Wall Peptidoglycan)

(2008) J. T. Park et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS