Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria

Backbone hydrogen bond energies in membrane proteins are insensitive to large changes in local water concentration

(2020) Henry J Lessen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterizing Membrane Association and Periplasmic Transfer of Bacterial Lipoproteins through Molecular Dynamics Simulations

(2020) Shanlin Rao et al.   STRUCTURE

Outer membrane protein size and LPS O-antigen define protective antibody targeting to the Salmonella surface

(2020) C. Coral Domínguez-Medina et al.   Nature Communications

High-Resolution In Situ NMR Spectroscopy of Bacterial Envelope Proteins in Outer Membrane Vesicles

(2020) Johannes Thoma et al.   BIOCHEMISTRY

Lipoprotein Lpp regulates the mechanical properties of the E. coli cell envelope

(2020) Marion Mathelié-Guinlet et al.   Nature Communications

The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism

(2020) Joanna Szczepaniak et al.   Nature Communications

Structure of a nascent membrane protein as it folds on the BAM complex

(2020) David Tomasek et al.   NATURE

LlpB represents a second subclass of lectin-like bacteriocins

(2019) Maarten G. K. Ghequire et al.   Microbial Biotechnology

Deprivation of the Periplasmic Chaperone SurA Reduces Virulence and Restores Antibiotic Susceptibility of Multidrug-Resistant Pseudomonas aeruginosa

(2019) Kristina Klein et al.   Frontiers in Microbiology

Movement of Arginine through OprD: The Energetics of Permeation and the Role of Lipopolysaccharide in Directing Arginine to the Protein

(2019) Firdaus Samsudin et al.   JOURNAL OF PHYSICAL CHEMISTRY B

The gram‐negative outer membrane modeler: Automated building of lipopolysaccharide‐rich bacterial outer membranes in four force fields

(2019) Fotis A. Baltoumas et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Outer Membrane Proteins OmpA, FhuA, OmpF, EstA, BtuB, and OmpX Have Unique Lipopolysaccharide Fingerprints

(2019) Jonathan Shearer et al.   Journal of Chemical Theory and Computation

Physical Properties of Bacterial Outer Membrane Models: Neutron Reflectometry & Molecular Simulation

(2019) Arwel V. Hughes et al.   BIOPHYSICAL JOURNAL

Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach

(2019) Hundeep Kaur et al.   JOURNAL OF BIOMOLECULAR NMR

Inhibition of autotransporter biogenesis by small molecules

(2019) Maurice Steenhuis et al.   MOLECULAR MICROBIOLOGY

Improper Coordination of BamA and BamD Results in Bam Complex Jamming by a Lipoprotein Substrate

(2019) Muralidhar Tata et al.   mBio

A Comprehensive Functional Characterization of Escherichia coli Lipid Genes

(2019) Aike Jeucken et al.   Cell Reports

Presence of substrate aids lateral gate separation in LptD

(2019) Karl P. Lundquist et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Modeling of Specific Lipopolysaccharide Binding Sites on a Gram-Negative Porin

(2019) Anusha Kesireddy et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Bacterial outer membrane proteins assemble via asymmetric interactions with the BamA β-barrel

(2019) Matthew T. Doyle et al.   Nature Communications

Profiling the E. coli membrane interactome captured in peptidisc libraries

(2019) Michael Luke Carlson et al.   eLife

Massive antibody discovery used to probe structure–function relationships of the essential outer membrane protein LptD

(2019) Kelly M Storek et al.   eLife

Structural Basis of the Subcellular Topology Landscape of Escherichia coli

(2019) Maria S. Loos et al.   Frontiers in Microbiology

Temperature-dependent regulation of the Escherichia coli lpxT gene

(2019) Barbara Sciandrone et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Intermembrane transport: Glycerophospholipid homeostasis of the Gram-negative cell envelope

(2019) Matthew J. Powers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stairway to Asymmetry: Five Steps to Lipid-Asymmetric Proteoliposomes

(2019) Marie Markones et al.   BIOPHYSICAL JOURNAL

The small molecule nitazoxanide selectively disrupts BAM-mediated folding of the outer membrane usher protein

(2019) John J. Psonis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chimeric peptidomimetic antibiotics against Gram-negative bacteria

(2019) Anatol Luther et al.   NATURE

A new antibiotic selectively kills Gram-negative pathogens

(2019) Yu Imai et al.   NATURE

A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier

(2019) Elizabeth M. Hart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug-Resistant Epimutants Exhibit Organ-Specific Stability and Induction during Murine Infections Caused by the Human Fungal Pathogen Mucor circinelloides

(2019) Zanetta Chang et al.   mBio

Formation of a β-barrel membrane protein is catalyzed by the interior surface of the assembly machine protein BamA

(2019) James Lee et al.   eLife

Measuring molecular order for lipid membrane phase studies: Linear relationship between Laurdan generalized polarization and deuterium NMR order parameter

(2019) Sherry See Wai Leung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Molecular characterization of the outer membrane of Pseudomonas aeruginosa

(2019) Cesar A. López et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria

(2019) Julia Vergalli et al.   NATURE REVIEWS MICROBIOLOGY

Architecture of the Cellulose Synthase Outer Membrane Channel and Its Association with the Periplasmic TPR Domain

(2019) Justin F. Acheson et al.   STRUCTURE

Folding Determinants of Transmembrane β-Barrels Using Engineered OMP Chimeras

(2018) Deepti Chaturvedi et al.   BIOCHEMISTRY

Lipoprotein Transport: Greasing the Machines of Outer Membrane Biogenesis

(2018) Marcin Grabowicz   BIOESSAYS

The Bam complex catalyzes efficient insertion of bacterial outer membrane proteins into membrane vesicles of variable lipid composition

(2018) Sunyia Hussain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Building Blocks of the Outer Membrane: Calculating a General Elastic Energy Model for β-Barrel Membrane Proteins

(2018) Henry J. Lessen et al.   Journal of Chemical Theory and Computation

Tight Turns of Outer Membrane Proteins: An Analysis of Sequence, Structure, and Hydrogen Bonding

(2018) Meghan Whitney Franklin et al.   JOURNAL OF MOLECULAR BIOLOGY

Discovery, research, and development of new antibiotics: the WHO priority list of antibiotic-resistant bacteria and tuberculosis

(2018) Evelina Tacconelli et al.   LANCET INFECTIOUS DISEASES

Engineering Asymmetric Lipid Vesicles: Accurate and Convenient Control of the Outer Leaflet Lipid Composition

(2018) Marie Markones et al.   LANGMUIR

Monoclonal antibody targeting the β-barrel assembly machine ofEscherichia coliis bactericidal

(2018) Kelly M. Storek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion

(2018) James Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ConvertingEscherichia coliinto an archaebacterium with a hybrid heterochiral membrane

(2018) Antonella Caforio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane protein insertion through a mitochondrial β-barrel gate

(2018) Alexandra I. C. Höhr et al.   SCIENCE

POTRA Domains, Extracellular Lid, and Membrane Composition Modulate the Conformational Stability of the β Barrel Assembly Factor BamA

(2018) Johannes Thoma et al.   STRUCTURE

The Escherichia coli Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling

(2018) Kerrie L. May et al.   mBio

Hitting with a BAM: Selective Killing by Lectin-Like Bacteriocins

(2018) Maarten G. K. Ghequire et al.   mBio

Structural basis for chitin acquisition by marine Vibrio species

(2018) Anuwat Aunkham et al.   Nature Communications

How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membrane proteins

(2018) Matthieu Chavent et al.   Nature Communications

A targeted boost-and-sort immunization strategy using Escherichia coli BamA identifies rare growth inhibitory antibodies

(2018) Rajesh Vij et al.   Scientific Reports

The WD40 Protein BamB Mediates Coupling of BAM Complexes into Assembly Precincts in the Bacterial Outer Membrane

(2018) Sachith D. Gunasinghe et al.   Cell Reports

Accurate in silico modeling of asymmetric bilayers based on biophysical principles

(2018) Milka Doktorova et al.   BIOPHYSICAL JOURNAL

Preparation of Asymmetric Liposomes Using a Phosphatidylserine Decarboxylase

(2018) Carina Drechsler et al.   BIOPHYSICAL JOURNAL

Prediction of the closed conformation and insights into the mechanism of the membrane enzyme LpxR

(2018) Graham M. Saunders et al.   BIOPHYSICAL JOURNAL

Simulation Study of Occk5 Functional Properties in Pseudomonas aeruginosa Outer Membranes

(2018) Joonseong Lee et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Sequence-Specific Solution NMR Assignments of the β-Barrel Insertase BamA to Monitor Its Conformational Ensemble at the Atomic Level

(2018) Jean-Baptiste Hartmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The outer membrane is an essential load-bearing element in Gram-negative bacteria

(2018) Enrique R. Rojas et al.   NATURE

Molecular dynamics modeling of Pseudomonas aeruginosa outer membranes

(2018) Ao Li et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Liquid crystalline bacterial outer membranes are critical for antibiotic susceptibility

(2018) Nicolò Paracini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C-terminal kink formation is required for lateral gating in BamA

(2018) Karl Lundquist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Escherichia coli β-Barrel Assembly Machinery Is Sensitized to Perturbations under High Membrane Fluidity

(2018) Kelly M. Storek et al.   JOURNAL OF BACTERIOLOGY

Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD

(2018) Minge Du et al.   NATURE

Viscous control of cellular respiration by membrane lipid composition

(2018) Itay Budin et al.   SCIENCE

Protein assemblies ejected directly from native membranes yield complexes for mass spectrometry

(2018) Dror S. Chorev et al.   SCIENCE

Impact of Membrane Phospholipid Alterations in Escherichia coli on Cellular Function and Bacterial Stress Adaptation

(2017) Veronica W. Rowlett et al.   JOURNAL OF BACTERIOLOGY

Conformational Changes That Coordinate the Activity of BamA and BamD Allowing β-Barrel Assembly

(2017) Anne L. McCabe et al.   JOURNAL OF BACTERIOLOGY

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding

(2017) Bob Schiffrin et al.   JOURNAL OF MOLECULAR BIOLOGY

Dynamics of OmpF Trimer Formation in the Bacterial Outer Membrane of Escherichia coli

(2017) Huilin Ma et al.   LANGMUIR

Heterogeneity in non-epitope loop sequence and outer membrane protein complexes alters antibody binding to the major porin protein PorB in serogroup B Neisseria meningitidis

(2017) Kathryn A. Matthias et al.   MOLECULAR MICROBIOLOGY

Redefining the essential trafficking pathway for outer membrane lipoproteins

(2017) Marcin Grabowicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flexibility in the Periplasmic Domain of BamA Is Important for Function

(2017) Lisa R. Warner et al.   STRUCTURE

Cardiolipin Synthesis and Outer Membrane Localization Are Required for Shigella flexneri Virulence

(2017) Rachael M. Rossi et al.   mBio

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

(2017) Carl A. Machutta et al.   Nature Communications

An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump

(2017) Zhao Wang et al.   eLife

Structural basis for maintenance of bacterial outer membrane lipid asymmetry

(2017) Javier Abellón-Ruiz et al.   Nature Microbiology

Structure of the MacAB–TolC ABC-type tripartite multidrug efflux pump

(2017) Anthony W. P. Fitzpatrick et al.   Nature Microbiology

Drugging Membrane Protein Interactions

(2016) Hang Yin et al.   Annual Review of Biomedical Engineering

Globular Protein Folding In Vitro and In Vivo

(2016) Martin Gruebele et al.   Annual Review of Biophysics

The Power of Asymmetry: Architecture and Assembly of the Gram-Negative Outer Membrane Lipid Bilayer

(2016) Jeremy C. Henderson et al.   Annual Review of Microbiology

When fast is better: protein folding fundamentals and mechanisms from ultrafast approaches

(2016) V. Munoz et al.   BIOCHEMICAL JOURNAL

A growing toolbox of techniques for studying  -barrel outer membrane protein folding and biogenesis

(2016) J. E. Horne et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Novel Kinetic Intermediates Populated along the Folding Pathway of the Transmembrane β-Barrel OmpA

(2016) Emily J. Danoff et al.   BIOCHEMISTRY

The influence of rough lipopolysaccharide structure on molecular interactions with mammalian antimicrobial peptides

(2016) Gianluca Bello et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Effects of protein crowding on membrane systems

(2016) Gernot Guigas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Synthesis and antimicrobial activity against Pseudomonas aeruginosa of macrocyclic β-hairpin peptidomimetic antibiotics containing N -methylated amino acids

(2016) Stefan U. Vetterli et al.   BIOORGANIC & MEDICINAL CHEMISTRY

BamA POTRA Domain Interacts with a Native Lipid Membrane Surface

(2016) Patrick J. Fleming et al.   BIOPHYSICAL JOURNAL

Full-Length OmpA: Structure, Function, and Membrane Interactions Predicted by Molecular Dynamics Simulations

(2016) Maite L. Ortiz-Suarez et al.   BIOPHYSICAL JOURNAL

Bilayer Properties of Lipid A from Various Gram-Negative Bacteria

(2016) Seonghoon Kim et al.   BIOPHYSICAL JOURNAL

Role of the Native Outer-Membrane Environment on the Transporter BtuB

(2016) Curtis Balusek et al.   BIOPHYSICAL JOURNAL

MreB-Dependent Organization of the E. coli Cytoplasmic Membrane Controls Membrane Protein Diffusion

(2016) Felix Oswald et al.   BIOPHYSICAL JOURNAL

Dynamics and Interactions of OmpF and LPS: Influence on Pore Accessibility and Ion Permeability

(2016) Dhilon S. Patel et al.   BIOPHYSICAL JOURNAL

Measuring the Viscosity of the Escherichia coli Plasma Membrane Using Molecular Rotors

(2016) Jacek T. Mika et al.   BIOPHYSICAL JOURNAL

Structure and function: Lipid A modifications in commensals and pathogens

(2016) Alex Steimle et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

A Supercomplex Spanning the Inner and Outer Membranes Mediates the Biogenesis of β-Barrel Outer Membrane Proteins in Bacteria

(2016) Yan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Translocation of a Biofilm-supporting Exopolysaccharide across the Bacterial Outer Membrane

(2016) Yan Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aromatic Side Chain Water-to-Lipid Transfer Free Energies Show a Depth Dependence across the Membrane Normal

(2016) Sarah K. McDonald et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Subnanometer Structure of an Asymmetric Model Membrane: Interleaflet Coupling Influences Domain Properties

(2016) Frederick A. Heberle et al.   LANGMUIR

Structural basis of outer membrane protein insertion by the BAM complex

(2016) Yinghong Gu et al.   NATURE

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins

(2016) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis

(2016) Wanatchaporn Arunmanee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of a stalled complex on the β-barrel assembly machine

(2016) James Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structure of the  -barrel assembly machinery complex

(2016) J. Bakelar et al.   SCIENCE

Membrane stiffness is modified by integral membrane proteins

(2016) Philip W. Fowler et al.   Soft Matter

OmpA: A Flexible Clamp for Bacterial Cell Wall Attachment

(2016) Firdaus Samsudin et al.   STRUCTURE

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM

(2016) Matthew G. Iadanza et al.   Nature Communications

Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins

(2016) Long Han et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pre-transition effects mediate forces of assembly between transmembrane proteins

(2016) Shachi Katira et al.   eLife

Dynamics of Crowded Vesicles: Local and Global Responses to Membrane Composition

(2016) Daniel A. Holdbrook et al.   PLoS One

Confined Mobility of TonB and FepA in Escherichia coli Membranes

(2016) Yoriko Lill et al.   PLoS One

Biogenesis of mitochondrial outer membrane proteins, problems and diseases

(2015) Lars Ellenrieder et al.   BIOLOGICAL CHEMISTRY

The β-barrel membrane protein insertase machinery from Gram-negative bacteria

(2015) Nicholas Noinaj et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Protein–protein interactions and the spatiotemporal dynamics of bacterial outer membrane proteins

(2015) Colin Kleanthous et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

How Tolerant are Membrane Simulations with Mismatch in Area per Lipid between Leaflets?

(2015) Soohyung Park et al.   Journal of Chemical Theory and Computation

Simulating Gram-Negative Bacterial Outer Membrane: A Coarse Grain Model

(2015) Huilin Ma et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Exploring the Existence of Lipid Rafts in Bacteria

(2015) Marc Bramkamp et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA

(2015) Rhys A. Dunstan et al.   MOLECULAR MICROBIOLOGY

Supramolecular assemblies underpin turnover of outer membrane proteins in bacteria

(2015) Patrice Rassam et al.   NATURE

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

Lipopolysaccharide is Inserted into the Outer Membrane through An Intramembrane Hole, A Lumen Gate, and the Lateral Opening of LptD

(2015) Yinghong Gu et al.   STRUCTURE

Structure of mycobacterial maltokinase, the missing link in the essential GlgE-pathway

(2015) Joana Fraga et al.   Scientific Reports

Methylation at the C-2 position of hopanoids increases rigidity in native bacterial membranes

(2015) Chia-Hung Wu et al.   eLife

Characterization of the E. coli proteome and its modifications during growth and ethanol stress

(2015) Boumediene Soufi et al.   Frontiers in Microbiology

Mechanistic studies of the biogenesis and folding of outer membrane proteins in vitro and in vivo: What have we learned to date?

(2014) Lindsay M. McMorran et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Membrane Defects Accelerate Outer Membrane β-Barrel Protein Folding

(2014) Emily J. Danoff et al.   BIOCHEMISTRY

The periplasmic domain of Escherichia coli outer membrane protein A can undergo a localized temperature dependent structural transition

(2014) Hiroaki Ishida et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

E. coli Outer Membrane and Interactions with OmpLA

(2014) Emilia L. Wu et al.   BIOPHYSICAL JOURNAL

Dynamics of the Serine Chemoreceptor in the Escherichia coli Inner Membrane: A High-Speed Single-Molecule Tracking Study

(2014) Dongmyung Oh et al.   BIOPHYSICAL JOURNAL

Quantifying Absolute Protein Synthesis Rates Reveals Principles Underlying Allocation of Cellular Resources

(2014) Gene-Wei Li et al.   CELL

X-ray structure, thermodynamics, elastic properties and MD simulations of cardiolipin/dimyristoylphosphatidylcholine mixed membranes

(2014) Alexander L. Boscia et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Structural and functional analysis of the β-barrel domain of BamA from Escherichia coli

(2014) Dongchun Ni et al.   FASEB JOURNAL

Outer Membrane Protein OmpW Participates with Small Multidrug Resistance Protein Member EmrE in Quaternary Cationic Compound Efflux

(2014) M. S. Beketskaia et al.   JOURNAL OF BACTERIOLOGY

Localization of Anionic Phospholipids in Escherichia coli Cells

(2014) P. M. Oliver et al.   JOURNAL OF BACTERIOLOGY

Effect of Divalent Cation Removal on the Structure of Gram-Negative Bacterial Outer Membrane Models

(2014) Luke A. Clifton et al.   LANGMUIR

Independent mobility of proteins and lipids in the plasma membrane ofEscherichia coli

(2014) Anja Nenninger et al.   MOLECULAR MICROBIOLOGY

Outer membrane  -barrel protein folding is physically controlled by periplasmic lipid head groups and BamA

(2014) D. Gessmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral Opening and Exit Pore Formation Are Required for BamA Function

(2014) Nicholas Noinaj et al.   STRUCTURE

Visualizing active membrane protein complexes by electron cryotomography

(2014) Vicki A.M. Gold et al.   Nature Communications

Versatile in vitro system to study translocation and functional integration of bacterial outer membrane proteins

(2014) Derrick Norell et al.   Nature Communications

Reconstitution of bacterial autotransporter assembly using purified components

(2014) Giselle Roman-Hernandez et al.   eLife

Structure of BamA, an essential factor in outer membrane protein biogenesis

(2014) Reinhard Albrecht et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Lipid Bilayer-Inserted Membrane Protein BamA of Escherichia coli Facilitates Insertion and Folding of Outer Membrane Protein A from Its Complex with Skp

(2013) Geetika J. Patel et al.   BIOCHEMISTRY

Bam Lipoproteins Assemble BamA in Vitro

(2013) Christine L. Hagan et al.   BIOCHEMISTRY

Absence of long-range diffusion of OmpA in E. coli is not caused by its peptidoglycan binding domain

(2013) Gertjan S Verhoeven et al.   BMC MICROBIOLOGY

Comparison of lipopolysaccharide structures of Bordetella pertussis clinical isolates from pre- and post-vaccine era

(2013) Sami AlBitar-Nehme et al.   CARBOHYDRATE RESEARCH

Folding and stability of outer membrane protein A (OmpA) from Escherichia coli in an amphipathic polymer, amphipol A8-35

(2013) Cosmin L. Pocanschi et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Asymmetric phospholipid: lipopolysaccharide bilayers; a Gram-negative bacterial outer membrane mimic

(2013) L. A. Clifton et al.   Journal of the Royal Society Interface

Structural insight into the biogenesis of β-barrel membrane proteins

(2013) Nicholas Noinaj et al.   NATURE

Fortifying the barrier: the impact of lipid A remodelling on bacterial pathogenesis

(2013) Brittany D. Needham et al.   NATURE REVIEWS MICROBIOLOGY

The structural basis of autotransporter translocation by TamA

(2013) Fabian Gruss et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular rheometry: direct determination of viscosity in Lo and Ld lipid phases via fluorescence lifetime imaging

(2013) Yilei Wu et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Methionine Mutations of Outer Membrane Protein X Influence Structural Stability and Beta-Barrel Unfolding

(2013) Deepti Chaturvedi et al.   PLoS One

Conformation-specific labeling of BamA and suppressor analysis suggest a cyclic mechanism for  -barrel assembly in Escherichia coli

(2013) N. W. Rigel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane protein thermodynamic stability may serve as the energy sink for sorting in the periplasm

(2013) C. Preston Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meningococcal Omp85 in Detergent-Extracted Outer Membrane Vesicle Vaccines Induces High Levels of Non-Functional Antibodies in Mice

(2013) E. Wedege et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Modulating lipid dynamics and membrane fluidity to drive rapid folding of a transmembrane barrel

(2013) Svetlana Rajkumar Maurya et al.   Scientific Reports

Reduced Lateral Mobility of Lipids and Proteins in Crowded Membranes

(2013) Joseph E. Goose et al.   PLoS Computational Biology

Membrane topology of Salmonella invasion protein SipB confers osmotolerance

(2012) Hiroshi Asakura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Kinetic Analysis of the Folding and Unfolding of OmpA in Urea and Guanidinium Chloride: Single and Parallel Pathways

(2012) Kell K. Andersen et al.   BIOCHEMISTRY

Stability and membrane interactions of an autotransport protein: MD simulations of the Hia translocator domain in a complex membrane environment

(2012) Daniel A. Holdbrook et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Conformational dynamics and membrane interactions of the E. coli outer membrane protein FecA: A molecular dynamics simulation study

(2012) Thomas J. Piggot et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phosphatidylcholine biosynthesis and function in bacteria

(2012) Otto Geiger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Hydrophobic Mismatch and Lipid Sorting Near OmpA in Mixed Bilayers: Atomistic and Coarse-Grained Simulations

(2012) Fuchang Yin et al.   BIOPHYSICAL JOURNAL

Is the C-terminal insertional signal in Gram-negative bacterial outer membrane proteins species-specific or not?

(2012) Nagarajan Paramasivam et al.   BMC GENOMICS

Curvature, Lipid Packing, and Electrostatics of Membrane Organelles: Defining Cellular Territories in Determining Specificity

(2012) Joëlle Bigay et al.   DEVELOPMENTAL CELL

Lipoproteins in bacteria: structures and biosynthetic pathways

(2012) Hiroshi Nakayama et al.   FEBS Journal

SoxS-dependent coregulation of ompN and ydbK in a multidrug-resistant Escherichia coli strain

(2012) Anna Fàbrega et al.   FEMS MICROBIOLOGY LETTERS

A Single Amino Acid Substitution Changes the Self-Assembly Status of a Type IV Piliation Secretin

(2012) Nicholas N. Nickerson et al.   JOURNAL OF BACTERIOLOGY

A Glycam-Based Force Field for Simulations of Lipopolysaccharide Membranes: Parametrization and Validation

(2012) Karl N. Kirschner et al.   Journal of Chemical Theory and Computation

Malleability of the Folding Mechanism of the Outer Membrane Protein PagP: Parallel Pathways and the Effect of Membrane Elasticity

(2012) Gerard H.M. Huysmans et al.   JOURNAL OF MOLECULAR BIOLOGY

Single-Molecule Imaging on Living Bacterial Cell Surface by High-Speed AFM

(2012) Hayato Yamashita et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of the motion of membrane proteins using high-speed atomic force microscopy

(2012) Ignacio Casuso et al.   Nature Nanotechnology

Single-molecule imaging in live bacteria cells

(2012) K. Ritchie et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates

(2012) B. K. Tan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LPS remodeling is an evolved survival strategy for bacteria

(2012) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of the Escherichia coli  -barrel assembly machine (Bam) is required for essential components to interact properly with substrate

(2012) D. P. Ricci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of Surface Protein Expression Reveals the Growth Pattern of the Gram-Negative Outer Membrane

(2012) Tristan S. Ursell et al.   PLoS Computational Biology

Deciphering the Acylation Pattern of Yersinia enterocolitica Lipid A

(2012) Mar Reinés et al.   PLoS Pathogens

The Lipopolysaccharide Core of Brucella abortus Acts as a Shield Against Innate Immunity Recognition

(2012) Raquel Conde-Álvarez et al.   PLoS Pathogens

Membrane Thickness Varies Around the Circumference of the Transmembrane Protein BtuB

(2011) Jeffrey F. Ellena et al.   BIOPHYSICAL JOURNAL

Single-Virus Tracking Reveals a Spatial Receptor-Dependent Search Mechanism

(2011) Eli Rothenberg et al.   BIOPHYSICAL JOURNAL

BamE Modulates the Escherichia coli Beta-Barrel Assembly Machine Component BamA

(2011) N. W. Rigel et al.   JOURNAL OF BACTERIOLOGY

The Fimbrial Usher FimD Follows the SurA-BamB Pathway for Its Assembly in the Outer Membrane of Escherichia coli

(2011) C. Palomino et al.   JOURNAL OF BACTERIOLOGY

Overcoming Hysteresis to Attain Reversible Equilibrium Folding for Outer Membrane Phospholipase A in Phospholipid Bilayers

(2011) C. Preston Moon et al.   JOURNAL OF MOLECULAR BIOLOGY

Association of Neighboring β-Strands of Outer Membrane Protein A in Lipid Bilayers Revealed by Site-Directed Fluorescence Quenching

(2011) Jörg H. Kleinschmidt et al.   JOURNAL OF MOLECULAR BIOLOGY

Electroporation of the E. coli and S. Aureus Membranes: Molecular Dynamics Simulations of Complex Bacterial Membranes

(2011) Thomas J. Piggot et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Side-chain hydrophobicity scale derived from transmembrane protein folding into lipid bilayers

(2011) C. P. Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipoprotein LptE is required for the assembly of LptD by the  -barrel assembly machine in the outer membrane of Escherichia coli

(2011) G. Chimalakonda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligand-gated diffusion across the bacterial outer membrane

(2011) B. W. Lepore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Outer Membrane Targeting of Pseudomonas aeruginosa Proteins Shows Variable Dependence on the Components of Bam and Lol Machineries

(2011) H. H. Hoang et al.   mBio

Phase Separation in Lipid Membranes

(2011) F. A. Heberle et al.   Cold Spring Harbor Perspectives in Biology

TonB-Dependent Transporters: Regulation, Structure, and Function

(2010) Nicholas Noinaj et al.   Annual Review of Microbiology

The liquid-ordered state comes of age

(2010) Ole G. Mouritsen   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Mobility of BtuB and OmpF in the Escherichia coli Outer Membrane: Implications for Dynamic Formation of a Translocon Complex

(2010) Jeff Spector et al.   BIOPHYSICAL JOURNAL

Mobility of Cytoplasmic, Membrane, and DNA-Binding Proteins in Escherichia coli

(2010) Mohit Kumar et al.   BIOPHYSICAL JOURNAL

The damage of outer membrane of Escherichia coli in the presence of TiO2 combined with UV light

(2010) Peng Liu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Membrane Proteins Diffuse as Dynamic Complexes with Lipids

(2010) Perttu S. Niemelä et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Association of Unfolded Outer Membrane Proteins

(2010) Alexandra Ebie Tan et al.   MACROMOLECULAR BIOSCIENCE

The transition state for folding of an outer membrane protein

(2010) G. H. M. Huysmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptidomimetic Antibiotics Target Outer-Membrane Biogenesis in Pseudomonas aeruginosa

(2010) N. Srinivas et al.   SCIENCE

Reconstitution of Outer Membrane Protein Assembly from Purified Components

(2010) C. L. Hagan et al.   SCIENCE

Monitoring Biophysical Properties of Lipid Membranes by Environment-Sensitive Fluorescent Probes

(2009) Alexander P. Demchenko et al.   BIOPHYSICAL JOURNAL

Phosphatidylcholine in membrane of Escherichia coli changes bacterial antigenicity

(2009) Fan Chen et al.   CANADIAN JOURNAL OF MICROBIOLOGY

Folding scene investigation: membrane proteins

(2009) Paula J Booth et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Transbilayer (flip-flop ) lipid motion and lipid scrambling in membranes

(2009) F.-Xabier Contreras et al.   FEBS LETTERS

Lipid compositions in Escherichia coli and Bacillus subtilis during growth as determined by MALDI-TOF and TOF/TOF mass spectrometry

(2009) Jennifer Gidden et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

The  -Barrel Outer Membrane Protein Assembly Complex of Neisseria meningitidis

(2009) E. B. Volokhina et al.   JOURNAL OF BACTERIOLOGY

Role of Periplasmic Chaperones and BamA (YaeT/Omp85) in Folding and Secretion of Intimin from Enteropathogenic Escherichia coli Strains

(2009) G. Bodelon et al.   JOURNAL OF BACTERIOLOGY

Escherichia coliK-12 Suppressor-free Mutants Lacking Early Glycosyltransferases and Late Acyltransferases

(2009) Gracjana Klein et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NanC Crystal Structure, a Model for Outer-Membrane Channels of the Acidic Sugar-Specific KdgM Porin Family

(2009) Christophe Wirth et al.   JOURNAL OF MOLECULAR BIOLOGY

Flip-Flop of Phospholipids in Vesicles: Kinetic Analysis with Time-Resolved Small-Angle Neutron Scattering

(2009) Minoru Nakano et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Stability of Asymmetric Lipid Bilayers Assessed by Molecular Dynamics Simulations

(2009) Santi Esteban-Martín et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Bam (Omp85) complex is involved in secretion of the autotransporter haemoglobin protease

(2009) A. Sauri et al.   MICROBIOLOGY-SGM

The BAM complex subunit BamE (SmpA) is required for membrane integrity, stalk growth and normal levels of outer membrane  -barrel proteins in Caulobacter crescentus

(2009) K. R. Ryan et al.   MICROBIOLOGY-SGM

High-resolution architecture of the outer membrane of the Gram-negative bacteriaRoseobacter denitrificans

(2009) Szymon Jarosławski et al.   MOLECULAR MICROBIOLOGY

An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms

(2009) Alice I Bartlett et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Interaction of an autotransporter passenger domain with BamA during its translocation across the bacterial outer membrane

(2009) Raffaele Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ABC transport system that maintains lipid asymmetry in the Gram-negative outer membrane

(2009) J. C. Malinverni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Tryptophan Microenvironment, Soluble Domain, and Vesicle Size on the Thermodynamics of Membrane Protein Folding: Lessons from the Transmembrane Protein OmpA†

(2008) Katheryn M. Sanchez et al.   BIOCHEMISTRY

Incorporation of Outer Membrane Protein OmpG in Lipid Membranes: Protein−lipid Interactions and β-Barrel Orientation†

(2008) V. Anbazhagan et al.   BIOCHEMISTRY

Protein−Lipid Interactions withFusobacterium nucleatumMajor Outer Membrane Protein FomA: Spin-Label EPR and Polarized Infrared Spectroscopy†

(2008) V. Anbazhagan et al.   BIOCHEMISTRY

The liquid-ordered phase in membranes

(2008) Peter J. Quinn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Energetics of Hydrophobic Matching in Lipid-Protein Interactions

(2008) Derek Marsh   BIOPHYSICAL JOURNAL

Liquid Ordered and Gel Phases of Lipid Bilayers: Fluorescent Probes Reveal Close Fluidity but Different Hydration

(2008) Gora M’Baye et al.   BIOPHYSICAL JOURNAL

Dissecting Membrane Insertion of Mitochondrial β-Barrel Proteins

(2008) Stephan Kutik et al.   CELL

TheEscherichia colibiofilm-promoting protein Antigen 43 does not contribute to intestinal colonization

(2008) Maria das Graças de Luna et al.   FEMS MICROBIOLOGY LETTERS

Lipid-engineeredEscherichia coliMembranes Reveal Critical Lipid Headgroup Size for Protein Function

(2008) Malin Wikström et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Barrel Proteins That Reside in theEscherichia coliOuter Membranein VivoDemonstrate Varied Folding Behaviorin Vitro

(2008) Nancy K. Burgess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Potential and Electrostatics of Phospholipid Bilayers with Asymmetric Transmembrane Distribution of Anionic Lipids

(2008) Andrey A. Gurtovenko et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Changes in membrane lipid composition in ethanol- and acid-adapted Oenococcus oeni cells: characterization of the cfa gene by heterologous complementation

(2008) C. Grandvalet et al.   MICROBIOLOGY-SGM

Variable stoichiometry of the TatA component of the twin-arginine protein transport system observed by in vivo single-molecule imaging

(2008) M. C. Leake et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of the outer membrane protein OprF ofPseudomonas aeruginosain a lipopolysaccharide membrane by computer simulation

(2008) T.P. Straatsma et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Protein folding: Are we there yet?

(2007) A. Clay Clark   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS