Neutrophil extracellular traps and neutrophil-derived mediators as possible biomarkers in bronchial asthma

GM-CSF instigates a dendritic cell - T cell inflammatory circuit that drives chronic asthma development

(2021) Samuel Philip Nobs et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors

(2021) Leonardo Cristinziano et al.   Cells

Vascular endothelial growth factors and angiopoietins as new players in mastocytosis

(2021) Simone Marcella et al.   CLINICAL AND EXPERIMENTAL MEDICINE

ELISA detection of MPO-DNA complexes in human plasma is error-prone and yields limited information on neutrophil extracellular traps formed in vivo

(2021) Hubert Hayden et al.   PLoS One

Adjuvants and Vaccines Used in Allergen-Specific Immunotherapy Induce Neutrophil Extracellular Traps

(2021) Jasmine Karacs et al.   Vaccines

Neutrophil extracellular traps in cancer

(2021) Leonardo Cristinziano et al.   SEMINARS IN CANCER BIOLOGY

Anaplastic Thyroid Cancer Cells Induce the Release of Mitochondrial Extracellular DNA Traps by Viable Neutrophils

(2020) Leonardo Cristinziano et al.   JOURNAL OF IMMUNOLOGY

Intersection of biology and therapeutics: type 2 targeted therapeutics for adult asthma

(2020) Michael C Peters et al.   LANCET

Serum IL-8 and VEGFA are Two Promising Diagnostic Biomarkers of Asthma-COPD Overlap Syndrome

(2020) Qunli Ding et al.   International Journal of Chronic Obstructive Pulmonary Disease

T2-“Low” Asthma: Overview and Management Strategies

(2020) Anne M. Fitzpatrick et al.   Journal of Allergy and Clinical Immunology-In Practice

Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia

(2020) Kristin M Hudock et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

(2020) Álvaro Teijeira et al.   IMMUNITY

Interleukin-33 facilitates cutaneous defense against Staphylococcus aureus by promoting the development of neutrophil extracellular trap

(2020) Xiaodi Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The role of neutrophils in host defense and disease

(2020) Heather K. Lehman et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

On the origin of low‐density neutrophils

(2020) Marwan Hassani et al.   JOURNAL OF LEUKOCYTE BIOLOGY

In vivo evidence for extracellular DNA trap formation

(2020) Shida Yousefi et al.   Cell Death & Disease

HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells

(2020) Giancarlo Marone et al.   Vaccines

Neutrophil extracellular traps amplify neutrophil recruitment and inflammation in neutrophilic asthma by stimulating the airway epithelial cells to activate the TLR4/ NF-κB pathway and secrete chemokines

(2020) Rongjun Wan et al.   Aging-US

LPS‐mediated neutrophil VEGF‐A release is modulated by cannabinoid receptor activation

(2020) Mariantonia Braile et al.   JOURNAL OF LEUKOCYTE BIOLOGY

DNA of neutrophil extracellular traps promotes cancer metastasis via CCDC25

(2020) Linbin Yang et al.   NATURE

Low‐Density Neutrophils in Systemic Lupus Erythematosus

(2020) Sen Hee Tay et al.   Arthritis & Rheumatology

Neutrophil extracellular traps in COVID-19

(2020) Yu Zuo et al.   JCI Insight

IL-33-induced neutrophil extracellular traps degrade fibronectin in a murine model of bronchopulmonary dysplasia

(2020) Rui Jin et al.   Cell Death Discovery

Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

(2020) Panagiotis Skendros et al.   JOURNAL OF CLINICAL INVESTIGATION

Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer

(2020) Yu Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Development of a Novel Multiplex Bead-based Assay for Measuring Autoantibodies on Flow Cytometric Platform

(2020) Rajni Chauhan et al.   IMMUNOLOGICAL INVESTIGATIONS

Untangling “NETosis” from NETs

(2019) Shida Yousefi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF

(2019) Eline Haspeslagh et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

(2019) Marrah E Lachowicz-Scroggins et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The potential role of CD 16 high CD 62L dim neutrophils in the allergic asthma

(2019) Sandra Ekstedt et al.   ALLERGY

Mast Cells, Angiogenesis and Lymphangiogenesis in Human Gastric Cancer

(2019) Giuseppe Sammarco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biological Roles of Neutrophil-Derived Granule Proteins and Cytokines

(2019) Marco Antonio Cassatella et al.   TRENDS IN IMMUNOLOGY

Mechanisms and therapeutic strategies for Non‐T2 Asthma

(2019) Eric Sze et al.   ALLERGY

Neutrophil extracellular traps and low-density granulocytes are associated with the interferon signature in systemic lupus erythematosus, but not in antiphospholipid syndrome

(2019) Lucas L van den Hoogen et al.   ANNALS OF THE RHEUMATIC DISEASES

Phenotypes and endotypes of adult asthma: Moving toward precision medicine

(2019) Ravdeep Kaur et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Serum levels of IL-5, IL-6, IL-8, IL-13 and IL-17A in pre-defined groups of adult patients with moderate and severe bronchial asthma

(2019) Denitsa Dimitrova et al.   RESPIRATORY MEDICINE

Circulating neutrophil and eosinophil extracellular traps are markers of severe asthma

(2019) Vanessa Granger et al.   ALLERGY

Neutrophil extracellular traps induced by IL-8 aggravate atherosclerosis via activation NF-κB signaling in macrophages

(2019) Zhujun An et al.   CELL CYCLE

Meeting the Challenge of Identifying New Treatments for Type 2-low Neutrophilic Asthma

(2019) Or Kalchiem-Dekel et al.   CHEST

Tezepelumab: a novel biological therapy for the treatment of severe uncontrolled asthma

(2019) Giancarlo Marone et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement

(2019) Brian L. Graham et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

GM-CSF in inflammation

(2019) John A. Hamilton   JOURNAL OF EXPERIMENTAL MEDICINE

T Follicular Helper Cell Subsets and the Associated Cytokine IL-21 in the Pathogenesis and Therapy of Asthma

(2019) Fang Gong et al.   Frontiers in Immunology

Myeloperoxidase: Its role for host defense, inflammation, and neutrophil function

(2018) Yasuaki Aratani   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Novel Role of IL (Interleukin)-1β in Neutrophil Extracellular Trap Formation and Abdominal Aortic AneurysmsHighlights

(2018) Akshaya K. Meher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The enigmatic role of the neutrophil in asthma: Friend, foe or indifferent?

(2018) R. J. Snelgrove et al.   CLINICAL AND EXPERIMENTAL ALLERGY

FcγR/ROS/CK2α Is the Key Inducer of NF-κB Activation in a Murine Model of Asthma

(2018) June-Mo Kim et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

 β2 -Adrenoceptors inhibit neutrophil extracellular traps in human polymorphonuclear leukocytes

(2018) Franca Marino et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Potential involvement of neutrophils in human thyroid cancer

(2018) Maria Rosaria Galdiero et al.   PLoS One

Understanding Asthma Phenotypes, Endotypes, and Mechanisms of Disease

(2018) Merin E. Kuruvilla et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Dysregulated Calcium Homeostasis in Cystic Fibrosis Neutrophils Leads to Deficient Antimicrobial Responses

(2018) Frank H. Robledo-Avila et al.   JOURNAL OF IMMUNOLOGY

Formyl-Peptide Receptors in Infection, Inflammation, and Cancer

(2018) Elisabeth Weiß et al.   TRENDS IN IMMUNOLOGY

Neutrophil extracellular trap formation requires OPA1-dependent glycolytic ATP production

(2018) Poorya Amini et al.   Nature Communications

Neutrophil extracellular traps induced by IL-8 promote diffuse large B cell lymphoma progression via the TLR9 signaling

(2018) Man Nie et al.   CLINICAL CANCER RESEARCH

Cysteinyl leukotriene 2 receptor promotes endothelial permeability, tumor angiogenesis, and metastasis

(2018) Ernest Duah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biologic and New Therapies in Asthma

(2017) Farnaz Tabatabaian et al.   IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA

The importance of being “pure” neutrophils

(2017) Federica Calzetti et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of IL-17F/frequent exacerbator endotype in asthma

(2017) Fabio L.M. Ricciardolo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Elevated serum levels of TNF-α, IL-8, and ECP can be involved in the development and progression of bronchial asthma

(2017) Xiao-Gang Jiang et al.   JOURNAL OF ASTHMA

Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide

(2017) Laurent L. Reber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation

(2017) Marie Toussaint et al.   NATURE MEDICINE

Neutrophilic Inflammation in Asthma and Association with Disease Severity

(2017) Anuradha Ray et al.   TRENDS IN IMMUNOLOGY

Personalized Medicine in Allergy

(2017) Matteo Ferrando et al.   Allergy Asthma & Immunology Research

Group V Secreted Phospholipase A2 Induces the Release of Proangiogenic and Antiangiogenic Factors by Human Neutrophils

(2017) Stefania Loffredo et al.   Frontiers in Immunology

Biologic Therapy and Novel Molecular Targets of Severe Asthma

(2017) Amber N. Pepper et al.   Journal of Allergy and Clinical Immunology-In Practice

Elevated plasma levels of vascular permeability factors in C1 inhibitor-deficient hereditary angioedema

(2016) S. Loffredo et al.   ALLERGY

T follicular helper (Tfh) cells in normal immune responses and in allergic disorders

(2016) G. Varricchi et al.   ALLERGY

Tumor-Produced Interleukin-8 Attracts Human Myeloid-Derived Suppressor Cells and Elicits Extrusion of Neutrophil Extracellular Traps (NETs)

(2016) C. Alfaro et al.   CLINICAL CANCER RESEARCH

Human neutrophils in the saga of cellular heterogeneity: insights and open questions

(2016) Patrizia Scapini et al.   IMMUNOLOGICAL REVIEWS

Formyl Peptide Receptor 2 Plays a Deleterious Role During Influenza A Virus Infections

(2016) Sergey Tcherniuk et al.   JOURNAL OF INFECTIOUS DISEASES

Neutrophil extracellular traps are associated with inflammation in chronic airway disease

(2016) Thomas K. Wright et al.   RESPIROLOGY

Coagulation induced by C3aR-dependent NETosis drives protumorigenic neutrophils during small intestinal tumorigenesis

(2016) Silvia Guglietta et al.   Nature Communications

Plasma Inflammatory Cytokine IL-4, IL-8, IL-10, and TNF-α Levels Correlate with Pulmonary Function in Patients with Asthma-Chronic Obstructive Pulmonary Disease (COPD) Overlap Syndrome

(2016) Ai-Xia Huang et al.   MEDICAL SCIENCE MONITOR

Therapeutic interventions in severe asthma

(2016) Giorgio Walter Canonica et al.   World Allergy Organization Journal

Omalizumab in patients with eosinophilic granulomatosis with polyangiitis: a 36-month follow-up study

(2015) Aikaterini Detoraki et al.   JOURNAL OF ASTHMA

Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors

(2015) Rosaria I. Staiano et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Cellular Mechanisms Underlying Eosinophilic and Neutrophilic Airway Inflammation in Asthma

(2015) Girolamo Pelaia et al.   MEDIATORS OF INFLAMMATION

Galangin attenuates airway remodelling by inhibiting TGF-β1-mediated ROS generation and MAPK/Akt phosphorylation in asthma

(2015) Ya-Nan Liu et al.   Scientific Reports

Phenotypic Diversity and Plasticity in Circulating Neutrophil Subpopulations in Cancer

(2015) Jitka Y. Sagiv et al.   Cell Reports

Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV1

(2015) Koa Hosoki et al.   PLoS One

Neutrophil extracellular traps in cancer progression

(2014) Jonathan Cools-Lartigue et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

β2 integrin mediates hantavirus-induced release of neutrophil extracellular traps

(2014) Martin J. Raftery et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NETosis: A New Factor in Tumor Progression and Cancer-Associated Thrombosis

(2014) Melanie Demers et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Neutrophil Extracellular Traps in Sepsis

(2014) Gabriela Camicia et al.   SHOCK

NETosis: how vital is it?

(2013) B. G. Yipp et al.   BLOOD

International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma

(2013) K. F. Chung et al.   EUROPEAN RESPIRATORY JOURNAL

Damage-Associated Molecular Patterns Control Neutrophil Recruitment

(2013) Keir Pittman et al.   Journal of Innate Immunity

A proposed role for neutrophil extracellular traps in cancer immunoediting

(2013) Sivan Berger-Achituv et al.   Frontiers in Immunology

Circulating Nucleosomes and Neutrophil Activation as Risk Factors for Deep Vein Thrombosis

(2012) Maurits L. van Montfoort et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Neutrophil Extracellular Traps Mediate a Host Defense Response to Human Immunodeficiency Virus-1

(2012) Tatsuya Saitoh et al.   Cell Host & Microbe

Multi-ethnic reference values for spirometry for the 3–95-yr age range: the global lung function 2012 equations

(2012) Philip H. Quanjer et al.   EUROPEAN RESPIRATORY JOURNAL

Neutrophil extracellular traps: Is immunity the second function of chromatin?

(2012) Volker Brinkmann et al.   JOURNAL OF CELL BIOLOGY

Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo

(2012) Bryan G Yipp et al.   NATURE MEDICINE

Tumor-Associated Neutrophils: New Targets for Cancer Therapy

(2011) A. D. Gregory et al.   CANCER RESEARCH

Eosinophil and neutrophil extracellular DNA traps in human allergic asthmatic airways

(2011) Ryszard Dworski et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome

(2011) Jan Lötvall et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

Angiogenesis and lymphangiogenesis in bronchial asthma

(2010) A. Detoraki et al.   ALLERGY

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps

(2009) S Yousefi et al.   CELL DEATH AND DIFFERENTIATION

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects

(2009) Aikaterini Detoraki et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Granulocyte-macrophage colony-stimulating factor expression in induced sputum and bronchial mucosa in asthma and COPD

(2009) S Saha et al.   THORAX

Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

(2008) Shida Yousefi et al.   NATURE MEDICINE