Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors

Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites

(2015) Caroline Turcotte et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages

(2014) Yasutaka Okabe et al.   CELL

Heme-Mediated SPI-C Induction Promotes Monocyte Differentiation into Iron-Recycling Macrophages

(2014) Malay Haldar et al.   CELL

Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation

(2014) Jia Xue et al.   IMMUNITY

Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival

(2014) Emmanuel L. Gautier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages

(2014) Christoph Schneider et al.   NATURE IMMUNOLOGY

The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

(2014) M. Rosas et al.   SCIENCE

Selective Activation of Cannabinoid Receptor 2 in Leukocytes Suppresses Their Engagement of the Brain Endothelium and Protects the Blood-Brain Barrier

(2013) Slava Rom et al.   AMERICAN JOURNAL OF PATHOLOGY

The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis

(2013) B Romano et al.   BRITISH JOURNAL OF PHARMACOLOGY

Macrophage Regulation of Tumor Responses to Anticancer Therapies

(2013) Michele De Palma et al.   CANCER CELL

Controlling 2-arachidonoylglycerol metabolism as an anti-inflammatory strategy

(2013) Mireille Alhouayek et al.   DRUG DISCOVERY TODAY

Cannabinoid receptor 1 controls human mucosal-type mast cell degranulation and maturation in situ

(2013) Koji Sugawara et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

(2013) Martin Guilliams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

Cannabinoid receptor trafficking in peripheral cells is dynamically regulated by a binary biochemical switch

(2012) Jonas Kleyer et al.   BIOCHEMICAL PHARMACOLOGY

Endocannabinoids limit excessive mast cell maturation and activation in human skin

(2012) Koji Sugawara et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Tumor associated macrophages and neutrophils in tumor progression

(2012) Maria R. Galdiero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of CB1 in immune modulation by cannabinoids

(2012) Barbara L.F. Kaplan   PHARMACOLOGY & THERAPEUTICS

Cannabinoid CB2 receptors protect against alcoholic liver disease by regulating Kupffer cell polarization in mice

(2011) Alexandre Louvet et al.   HEPATOLOGY

Macrophage regulation of tumor angiogenesis: Implications for cancer therapy

(2011) Mario Leonardo Squadrito et al.   MOLECULAR ASPECTS OF MEDICINE

Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice

(2011) Fabiana Piscitelli et al.   Nutrition & Metabolism

Endocannabinoids Generated by Ca2+ or by Metabotropic Glutamate Receptors Appear to Arise from Different Pools of Diacylglycerol Lipase

(2011) Longhua Zhang et al.   PLoS One

Functionally selective cannabinoid receptor signalling: Therapeutic implications and opportunities

(2010) Barbara Bosier et al.   BIOCHEMICAL PHARMACOLOGY

CB2: a cannabinoid receptor with an identity crisis

(2010) Brady K Atwood et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid Receptors, CB1 and CB2, as Novel Targets for Inhibition of Non-Small Cell Lung Cancer Growth and Metastasis

(2010) A. Preet et al.   Cancer Prevention Research

Production of Vascular Endothelial Growth Factors from Human Lung Macrophages Induced by Group IIA and Group X Secreted Phospholipases A2

(2010) F. Granata et al.   JOURNAL OF IMMUNOLOGY

Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight

(2010) Vincenzo Di Marzo   NATURE NEUROSCIENCE

CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages

(2009) K. H. Han et al.   CARDIOVASCULAR RESEARCH

Inhibition of Secretory Phospholipase A2-Induced Cytokine Production in Human Lung Macrophages by Budesonide

(2009) Massimo Triggiani et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

(2009) G. Solinas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways

(2008) Fabrizio Montecucco et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo

(2008) Tiziana Bisogno et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cannabinoids reduce granuloma-associated angiogenesis in rats by controlling transcription and expression of mast cell protease-5

(2008) D De Filippis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of Ca2+ influx by surfactant in NR8383 alveolar macrophages

(2008) R. Castro et al.   INFLAMMATION RESEARCH

Tetrahydrolipstatin Analogues as Modulators of Endocannabinoid 2-Arachidonoylglycerol Metabolism

(2008) Giorgio Ortar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets

(2008) Isabel Matias et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY