Degradation of lipid droplets by chimeric autophagy-tethering compounds

Lipophagy-derived fatty acids undergo extracellular efflux via lysosomal exocytosis

(2020) Wenqi Cui et al.   Autophagy

Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery

(2020) George M. Burslem et al.   CELL

An AMPK–caspase-6 axis controls liver damage in nonalcoholic steatohepatitis

(2020) Peng Zhao et al.   SCIENCE

Emerging New Concepts of Degrader Technologies

(2020) Yu Ding et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Huntingtin Lowering Strategies for Disease Modification in Huntington’s Disease

(2019) Sarah J. Tabrizi et al.   NEURON

Generation of hyperlipidemic rabbit models using multiple sgRNAs targeted CRISPR/Cas9 gene editing system

(2019) Tingting Yuan et al.   Lipids in Health and Disease

Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds

(2019) Zhaoyang Li et al.   NATURE

Effects of total parenteral nutrition on drug metabolism gene expression in mice

(2019) Christina Ferrucci-Da Silva et al.   Acta Pharmaceutica Sinica B

Oleic acid is a potent inducer for lipid droplet accumulation through its esterification to glycerol by diacylglycerol acyltransferase in primary cortical astrocytes

(2019) Shingo Nakajima et al.   BRAIN RESEARCH

AUTACs: Cargo-Specific Degraders Using Selective Autophagy

(2019) Daiki Takahashi et al.   MOLECULAR CELL

Nonalcoholic Fatty Liver Disease Induced by High-Fat Diet in C57bl/6 Models

(2019) Leonardo Recena Aydos et al.   Nutrients

Nonalcoholic Fatty Liver Disease Progresses into Severe NASH when Physiological Mechanisms of Tissue Homeostasis Collapse

(2018) Silvia Sookoian et al.   Annals of Hepatology

Forced lipophagy reveals that lipid droplets are required for early embryonic development in mouse

(2018) Takayuki Tatsumi et al.   DEVELOPMENT

Plin4-Dependent Lipid Droplets Hamper Neuronal Mitophagy in the MPTP/p-Induced Mouse Model of Parkinson’s Disease

(2018) Xiaojuan Han et al.   Frontiers in Neuroscience

Recent Advances in Fluorescent Probes for Lipid Droplets

(2018) Tkhe Fam et al.   Materials

Lipid Droplets in Health and Disease

(2017) Gizem Onal et al.   Lipids in Health and Disease

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism

(2016) Fei Xiao et al.   Science Signaling

BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism

(2016) Fei Xiao et al.   Science Signaling

Visualizing Compound Distribution during Zebrafish Embryo Development: The Effects of Lipophilicity and DMSO

(2015) Coco de Koning et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration

(2015) Lucy Liu et al.   CELL

Imaging of neutral lipids by oil red O for analyzing the metabolic status in health and disease

(2013) Annika Mehlem et al.   Nature Protocols

An Optimized Histochemical Method to Assess Skeletal Muscle Glycogen and Lipid Stores Reveals Two Metabolically Distinct Populations of Type I Muscle Fibers

(2013) Clara Prats et al.   PLoS One

Regulation of lipid stores and metabolism by lipophagy

(2012) K Liu et al.   CELL DEATH AND DIFFERENTIATION

Catabolism of amino acids in livers from cafeteria-fed rats

(2012) Cristiane Vizioli de Castro Ghizoni et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Regulation of lipid droplets by autophagy

(2011) Hanqing Dong et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

(2010) Irina A. Kirpich et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Defects in Innate Immunity Predispose C57BL/6J-Leprdb/Leprdb Mice to Infection by Staphylococcus aureus

(2008) S. Park et al.   INFECTION AND IMMUNITY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY