Leptin receptor-expressing pericytes mediate access of hypothalamic feeding centers to circulating leptin

Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia

(2020) Maiko T. Uemura et al.   Frontiers in Aging Neuroscience

Severe obesity, increasing age and male sex are independently associated with worse in-hospital outcomes, and higher in-hospital mortality, in a cohort of patients with COVID-19 in the Bronx, New York

(2020) Leonidas Palaiodimos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Tanycyte-Independent Control of Hypothalamic Leptin Signaling

(2019) Sooyeon Yoo et al.   Frontiers in Neuroscience

New Neuroscience of Homeostasis and Drives for Food, Water, and Salt

(2019) Bradford B. Lowell   NEW ENGLAND JOURNAL OF MEDICINE

IFN-γ drives inflammatory bowel disease pathogenesis through VE-cadherin–directed vascular barrier disruption

(2019) Victoria Langer et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of PI3K/Akt and MEK/ERK Signalling in cAMP/Epac-Mediated Endothelial Barrier Stabilisation

(2019) Dursun Gündüz et al.   Frontiers in Physiology

Discontinuation of Imatinib in a Child With Chronic Myeloid Leukemia

(2019) Preethi Jeyaraman et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors

(2018) Anand Venkataraman et al.   NATURE METHODS

Leptin and the maintenance of elevated body weight

(2018) Warren W. Pan et al.   NATURE REVIEWS NEUROSCIENCE

Microvascular Mural Cell Organotypic Heterogeneity and Functional Plasticity

(2018) Annegret Holm et al.   TRENDS IN CELL BIOLOGY

Leptin Receptor Expression in Mouse Intracranial Perivascular Cells

(2018) Xuefeng Yuan et al.   Frontiers in Neuroanatomy

Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase

(2018) Yuanqing Gao et al.   Molecular Metabolism

The LepR-mediated leptin transport across brain barriers controls food reward

(2018) Alessandro Di Spiezio et al.   Molecular Metabolism

Genetic identification of leptin neural circuits in energy and glucose homeostases

(2018) Jie Xu et al.   NATURE

Epac1−/− mice have elevated baseline permeability and do not respond to histamine as measured with dynamic contrast-enhanced magnetic resonance imaging with contrast agents of different molecular weights

(2018) Fitz-Roy E. Curry et al.   Acta Physiologica

N-cadherin signaling via Trio assembles adherens junctions to restrict endothelial permeability

(2018) Kevin Kruse et al.   JOURNAL OF CELL BIOLOGY

Endothelial Wnt/β-catenin signaling reduces immune cell infiltration in multiple sclerosis

(2017) Justin E. Lengfeld et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased microvascular permeability in mice lacking Epac1 (Rapgef3)

(2016) R. K. Kopperud et al.   Acta Physiologica

Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control

(2016) Tina Djogo et al.   Cell Metabolism

Epac2a-null mice exhibit obesity-prone nature more susceptible to leptin resistance

(2016) M Hwang et al.   INTERNATIONAL JOURNAL OF OBESITY

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

(2016) Roman A Romanov et al.   NATURE NEUROSCIENCE

Pericytes of the neurovascular unit: key functions and signaling pathways

(2016) Melanie D Sweeney et al.   NATURE NEUROSCIENCE

Differential and opposing effects of imatinib on LPS- and ventilator-induced lung injury

(2015) E. Letsiou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Targeting Abl Kinases to Regulate Vascular Leak During Sepsis and Acute Respiratory Distress Syndrome

(2015) A. N. Rizzo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

NG2-glia and their functions in the central nervous system

(2015) L. Dimou et al.   GLIA

What is a pericyte?

(2015) David Attwell et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells

(2015) Thamotharampillai Dileepan et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of Astrocytes in Leptin Signaling

(2015) Yuping Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Transgenic Mice for Intersectional Targeting of Neural Sensors and Effectors with High Specificity and Performance

(2015) Linda Madisen et al.   NEURON

Incidence of Development of Obesity After Heart Transplantation According to the Calcineurin Inhibitor

(2015) R. López-Vilella et al.   TRANSPLANTATION PROCEEDINGS

TRAP-seq defines markers for novel populations of hypothalamic and brainstem LepRb neurons

(2015) Margaret B. Allison et al.   Molecular Metabolism

Hypothalamic Tanycytes Are an ERK-Gated Conduit for Leptin into the Brain

(2014) Eglantine Balland et al.   Cell Metabolism

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

(2014) Jae Geun Kim et al.   NATURE NEUROSCIENCE

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Imatinib induces body mass changes in women with chronic myeloid leukemia

(2013) Massimo Breccia et al.   ANNALS OF HEMATOLOGY

How calcium signals in myocytes and pericytes are integrated across in situ microvascular networks and control microvascular tone

(2013) Lyudmyla Borysova et al.   CELL CALCIUM

Extensive regenerative plasticity among adult NG2-glia populations is exclusively based on self-renewal

(2013) Sarah C. Robins et al.   GLIA

Abl Family Kinases Regulate Endothelial Barrier Function In Vitro and in Mice

(2013) Elizabeth M. Chislock et al.   PLoS One

Evidence for NG2-glia Derived, Adult-Born Functional Neurons in the Hypothalamus

(2013) Sarah C. Robins et al.   PLoS One

Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor

(2013) Zhiying Li et al.   Molecular Metabolism

Significant weight gain in patients with chronic myeloid leukemia after imatinib therapy

(2012) E. Aduwa et al.   BLOOD

Effective Treatment of Edema and Endothelial Barrier Dysfunction With Imatinib

(2012) Jurjan Aman et al.   CIRCULATION

Enhanced Leptin Sensitivity, Reduced Adiposity, and Improved Glucose Homeostasis in Mice Lacking Exchange Protein Directly Activated by Cyclic AMP Isoform 1

(2012) J. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

(2012) Robert D. Bell et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Induction of Leptin Resistance by Activation of cAMP-Epac Signaling

(2011) Makoto Fukuda et al.   Cell Metabolism

Age-dependent fate and lineage restriction of single NG2 cells

(2011) X. Zhu et al.   DEVELOPMENT

Genetic Identification of GnRH Receptor Neurons: A New Model for Studying Neural Circuits Underlying Reproductive Physiology in the Mouse Brain

(2011) Shuping Wen et al.   ENDOCRINOLOGY

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels

(2010) Laurence E. Ring et al.   JOURNAL OF CLINICAL INVESTIGATION

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Angiotensin II induced cerebral microvascular inflammation and increased blood–brain barrier permeability via oxidative stress

(2010) M. Zhang et al.   NEUROSCIENCE

The arcuate nucleus as a circumventricular organ in the mouse

(2010) Philippe Ciofi   NEUROSCIENCE LETTERS

The Geometry of Leptin Action in the Brain: More Complicated Than a Simple ARC

(2009) Martin G. Myers et al.   Cell Metabolism

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Astrocyte Leptin Receptor (ObR) and Leptin Transport in Adult-Onset Obese Mice

(2008) Weihong Pan et al.   ENDOCRINOLOGY

Calcineurin inhibitors and post-transplant weight gain

(2008) ALPASLAN ERSOY et al.   NEPHROLOGY