Differential and opposing effects of imatinib on LPS- and ventilator-induced lung injury

Imatinib-Induced Bone Edema: Case Report and Review of Literature

(2017) Lucas Vieira dos Santos et al.   Journal of the National Comprehensive Cancer Network

Protein kinase G increases antioxidant function in lung microvascular endothelial cells by inhibiting the c-Abl tyrosine kinase

(2014) R. Scott Stephens et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Paxillin mediates stretch-induced Rho signaling and endothelial permeability via assembly of paxillin-p42/44MAPK-GEF-H1 complex

(2014) Grzegorz Gawlak et al.   FASEB JOURNAL

Reversal of Vascular Leak with Imatinib

(2013) Jurjan Aman et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Endothelial adherens junctions at a glance

(2013) E. Dejana et al.   JOURNAL OF CELL SCIENCE

Ventilator-Induced Lung Injury

(2013) Arthur S. Slutsky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Abl Family Kinases Regulate Endothelial Barrier Function In Vitro and in Mice

(2013) Elizabeth M. Chislock et al.   PLoS One

Abl kinases are required for vascular function, Tie2 expression, and angiopoietin-1-mediated survival

(2013) E. M. Chislock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF-κB activation in myeloid cells mediates ventilator-induced lung injury

(2013) Yi-An Ko et al.   RESPIRATORY RESEARCH

Stimulation of Rho signaling by pathologic mechanical stretch is a “second hit” to Rho-independent lung injury induced by IL-6

(2012) Anna A. Birukova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Effective Treatment of Edema and Endothelial Barrier Dysfunction With Imatinib

(2012) Jurjan Aman et al.   CIRCULATION

Hypercapnic acidosis attenuates ventilation-induced lung injury by a nuclear factor-κB–dependent mechanism

(2012) Maya Contreras et al.   CRITICAL CARE MEDICINE

Iloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury

(2012) A. A. Birukova et al.   EUROPEAN RESPIRATORY JOURNAL

The acute respiratory distress syndrome

(2012) Michael A. Matthay et al.   JOURNAL OF CLINICAL INVESTIGATION

Type 2 Deiodinase and Host Responses of Sepsis and Acute Lung Injury

(2011) Shwu-Fan Ma et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Imatinib treatment inhibit IL-6, IL-8, NF-KB and AP-1 production and modulate intracellular calcium in CML patients

(2011) Roberto Ciarcia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effect of Nilotinib on Bleomycin-Induced Acute Lung Injury and Pulmonary Fibrosis in Mice

(2011) Chin Kook Rhee et al.   RESPIRATION

The Abl and Arg non-receptor tyrosine kinases regulate different zones of stress fiber, focal adhesion, and contractile network localization in spreading fibroblasts

(2010) Justin G. Peacock et al.   Cytoskeleton

FTY720-induced human pulmonary endothelial barrier enhancement is mediated by c-Abl

(2010) L. Wang et al.   EUROPEAN RESPIRATORY JOURNAL

Abl Tyrosine Kinase Phosphorylates Nonmuscle Myosin Light Chain Kinase to Regulate Endothelial Barrier Function

(2010) Steven M. Dudek et al.   MOLECULAR BIOLOGY OF THE CELL

ABL Tyrosine Kinases: Evolution of Function, Regulation, and Specificity

(2010) J. Colicelli   Science Signaling

The physical basis of ventilator-induced lung injury

(2010) Maria Plataki et al.   Expert Review of Respiratory Medicine

Mechanical stretch enhances IL-8 production in pulmonary microvascular endothelial cells

(2009) Mai Iwaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Phosphorylation of Caveolin-1 Regulates Oxidant–Induced Pulmonary Vascular Permeability via Paracellular and Transcellular Pathways

(2009) Yu Sun et al.   CIRCULATION RESEARCH

Mechanisms of Transendothelial Migration of Leukocytes

(2009) William A. Muller   CIRCULATION RESEARCH

Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts

(2009) W. D. Bradley et al.   JOURNAL OF CELL SCIENCE

Heat shock protein 90 inhibitors attenuate LPS-induced endothelial hyperpermeability

(2008) Anuran Chatterjee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells

(2008) Audrey Sirvent et al.   BIOLOGY OF THE CELL

Breaking the VE-cadherin bonds

(2008) Julie Gavard   FEBS LETTERS

Endothelial pathomechanisms in acute lung injury

(2008) Nikolaos A. Maniatis et al.   VASCULAR PHARMACOLOGY