Genetic identification of leptin neural circuits in energy and glucose homeostases

Minireview: CNS Mechanisms of Leptin Action

(2016) Jonathan N. Flak et al.   MOLECULAR ENDOCRINOLOGY

Dynamic GABAergic afferent modulation of AgRP neurons

(2016) Alastair S Garfield et al.   NATURE NEUROSCIENCE

A Postsynaptic AMPK→p21-Activated Kinase Pathway Drives Fasting-Induced Synaptic Plasticity in AgRP Neurons

(2016) Dong Kong et al.   NEURON

Cell type-specific transcriptomics of hypothalamic energy-sensing neuron responses to weight-loss

(2015) Fredrick E Henry et al.   eLife

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

(2014) Randall J. Platt et al.   CELL

20 YEARS OF LEPTIN: Leptin at 20: an overview

(2014) Jeffrey Friedman   JOURNAL OF ENDOCRINOLOGY

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

(2014) Rachel J Perry et al.   NATURE MEDICINE

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

(2014) Tessa G. Montague et al.   NUCLEIC ACIDS RESEARCH

Narrative Review: The Role of Leptin in Human Physiology: Emerging Clinical Applications

(2013) Theodore Kelesidis   ANNALS OF INTERNAL MEDICINE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity

(2013) Darren Opland et al.   Molecular Metabolism

GABAergic RIP-Cre Neurons in the Arcuate Nucleus Selectively Regulate Energy Expenditure

(2012) Dong Kong et al.   CELL

Molecular Profiling of Activated Neurons by Phosphorylated Ribosome Capture

(2012) Zachary A. Knight et al.   CELL

Deciphering a neuronal circuit that mediates appetite

(2012) Qi Wu et al.   NATURE

Fasting Activation of AgRP Neurons Requires NMDA Receptors and Involves Spinogenesis and Increased Excitatory Tone

(2012) Tiemin Liu et al.   NEURON

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

(2011) Michael J. Krashes et al.   JOURNAL OF CLINICAL INVESTIGATION

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons

(2011) Linh Vong et al.   NEURON

Leptin and the Central Nervous System Control of Glucose Metabolism

(2011) Gregory J. Morton et al.   PHYSIOLOGICAL REVIEWS

Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

(2010) T. Fujikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuromedin B and Gastrin-Releasing Peptide Excite Arcuate Nucleus Neuropeptide Y Neurons in a Novel Transgenic Mouse Expressing Strong Renilla Green Fluorescent Protein in NPY Neurons

(2009) A. N. van den Pol et al.   JOURNAL OF NEUROSCIENCE

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance

(2008) Qingchun Tong et al.   NATURE NEUROSCIENCE

Collective and Individual Functions of Leptin Receptor Modulated Neurons Controlling Metabolism and Ingestion

(2007) Esther van de Wall et al.   ENDOCRINOLOGY