Organoids and organs-on-chips: Insights into human gut-microbe interactions
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Organoids and organs-on-chips: Insights into human gut-microbe interactions
Authors
Keywords
microbiota, microbe, organoid, co-culture, intestine, bacteria, virus, in vitro, models, host, organ-on-a-chip, epithelium, infection
Journal
Cell Host & Microbe
Volume 29, Issue 6, Pages 867-878
Publisher
Elsevier BV
Online
2021-06-09
DOI
10.1016/j.chom.2021.04.002
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Genomic aberrations after short-term exposure to colibactin-producing E. coli transform primary colon epithelial cells
- (2021) Amina Iftekhar et al. Nature Communications
- Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents
- (2020) Jens Walter et al. CELL
- Lactobacillus Protects Against S. Typhimurium –Induced Intestinal Inflammation by Determining the Fate of Epithelial Proliferation and Differentiation
- (2020) Xiaoxi Lu et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Host responses to mucosal biofilms in the lung and gut
- (2020) Jada C. Domingue et al. Mucosal Immunology
- Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli
- (2020) Cayetano Pleguezuelos-Manzano et al. NATURE
- Commercialization of Organoids
- (2020) Deepak Choudhury et al. TRENDS IN MOLECULAR MEDICINE
- Mucosal microbial load in Crohn's disease: A potential predictor of response to faecal microbiota transplantation
- (2020) Guillaume Sarrabayrouse et al. EBioMedicine
- Effects of Antibiotic Pretreatment of an Ulcerative Colitis-Derived Fecal Microbial Community on the Integration of Therapeutic Bacteria In Vitro
- (2020) Kaitlyn Oliphant et al. mSystems
- High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells
- (2020) Joep Beumer et al. CELL
- Development of a scalable co-culture system for gut anaerobes and human colon epithelium
- (2020) Nobuo Sasaki et al. GASTROENTEROLOGY
- Infection of bat and human intestinal organoids by SARS-CoV-2
- (2020) Jie Zhou et al. NATURE MEDICINE
- Colibactin DNA-damage signature indicates mutational impact in colorectal cancer
- (2020) Paulina J. Dziubańska-Kusibab et al. NATURE MEDICINE
- SARS-CoV-2 productively infects human gut enterocytes
- (2020) Mart M. Lamers et al. SCIENCE
- Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium
- (2020) Ozge Kayisoglu et al. GUT
- Development of caecaloids to study host–pathogen interactions: new insights into immunoregulatory functions of Trichuris muris extracellular vesicles in the caecum
- (2020) María A. Duque-Correa et al. INTERNATIONAL JOURNAL FOR PARASITOLOGY
- Direct On-Chip Differentiation of Intestinal Tubules from Induced Pluripotent Stem Cells
- (2020) Elena Naumovska et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Human organoids: model systems for human biology and medicine
- (2020) Jihoon Kim et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Homeostatic mini-intestines through scaffold-guided organoid morphogenesis
- (2020) Mikhail Nikolaev et al. NATURE
- The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress
- (2020) Michael Bauer et al. Nature Communications
- Rotavirus induces intercellular calcium waves through ADP signaling
- (2020) Alexandra L. Chang-Graham et al. SCIENCE
- Long‐term expanding human airway organoids for disease modeling
- (2019) Norman Sachs et al. EMBO JOURNAL
- Evaluating S. flexneri pathogenesis in the human enteroid model
- (2019) Sridevi Ranganathan et al. INFECTION AND IMMUNITY
- Human intestinal enteroids as a model system of Shigella pathogenesis
- (2019) Benjamin J. Koestler et al. INFECTION AND IMMUNITY
- Novel chimeric gene therapy vectors based on Adeno-associated virus (AAV) and four different mammalian bocaviruses (BoV)
- (2019) Julia Fakhiri et al. Molecular Therapy-Methods & Clinical Development
- Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis
- (2019) Nobuhiro Nakamoto et al. Nature Microbiology
- Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection
- (2019) Loryn Holokai et al. PLoS Pathogens
- Mucus Architecture and Near-Surface Swimming Affect Distinct Salmonella Typhimurium Infection Patterns along the Murine Intestinal Tract
- (2019) Markus Furter et al. Cell Reports
- A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip
- (2019) Sasan Jalili-Firoozinezhad et al. Nature Biomedical Engineering
- A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability
- (2019) Georgia Wilke et al. Cell Host & Microbe
- Mapping human microbiome drug metabolism by gut bacteria and their genes
- (2019) Michael Zimmermann et al. NATURE
- An in vitro intestinal platform with a self-sustaining oxygen gradient to study the human gut/microbiome interface
- (2019) Raehyun Kim et al. Biofabrication
- Photopatterned Membranes and Chemical Gradients Enable Scalable Phenotypic Organization of Primary Human Colon Epithelial Models
- (2019) Samuel S. Hinman et al. ANALYTICAL CHEMISTRY
- A three-dimensional immunocompetent intestine-on-chip model as in vitro platform for functional and microbial interaction studies
- (2019) Michelle Maurer et al. BIOMATERIALS
- Bioengineered Human Organ-on-Chip Reveals Intestinal Microenvironment and Mechanical Forces Impacting Shigella Infection
- (2019) Alexandre Grassart et al. Cell Host & Microbe
- Development of a Gut-on-a-Chip Model for High Throughput Disease Modeling and Drug Discovery
- (2019) Claudia Beaurivage et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A deeper understanding of intestinal organoid metabolism revealed by combining fluorescence lifetime imaging microscopy (FLIM) and extracellular flux analyses
- (2019) Irina A. Okkelman et al. Redox Biology
- Lactobacillus accelerates ISCs regeneration to protect the integrity of intestinal mucosa through activation of STAT3 signaling pathway induced by LPLs secretion of IL-22
- (2018) Qihang Hou et al. CELL DEATH AND DIFFERENTIATION
- Polarised epithelial monolayers of the gastric mucosa reveal insights into mucosal homeostasis and defence against infection
- (2018) Francesco Boccellato et al. GUT
- PDGFRα+pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo
- (2018) Gediminas Greicius et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
- (2018) Christine M. Dejea et al. SCIENCE
- The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells
- (2018) Nadège Bossuet-Greif et al. mBio
- Modelling Cryptosporidium infection in human small intestinal and lung organoids
- (2018) Inha Heo et al. Nature Microbiology
- Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
- (2018) Krijn K. Dijkstra et al. CELL
- Intestinal barrier dysfunction orchestrates the onset of inflammatory host–microbiome cross-talk in a human gut inflammation-on-a-chip
- (2018) Woojung Shin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crosstalk between the microbiome and epigenome: messages from bugs
- (2017) Yufeng Qin et al. JOURNAL OF BIOCHEMISTRY
- Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function
- (2017) Olivier Y. F. Henry et al. LAB ON A CHIP
- Enteroviruses infect human enteroids and induce antiviral signaling in a cell lineage-specific manner
- (2017) Coyne G. Drummond et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
- (2017) Leore T. Geller et al. SCIENCE
- Lipopolysaccharide from Crypt-Specific Core Microbiota Modulates the Colonic Epithelial Proliferation-to-Differentiation Balance
- (2017) Tomoaki Naito et al. mBio
- A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions
- (2017) Gaelle Noel et al. Scientific Reports
- Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium
- (2017) David R Hill et al. eLife
- Nonsteroidal Anti-Inflammatory Drug-Induced Leaky Gut Modeled Using Polarized Monolayers of Primary Human Intestinal Epithelial Cells
- (2017) Aadra P. Bhatt et al. ACS Infectious Diseases
- Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus
- (2017) Jie Zhou et al. Science Advances
- The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites
- (2016) Gerard E. Kaiko et al. CELL
- Modeling infectious diseases and host-microbe interactions in gastrointestinal organoids
- (2016) Sina Bartfeld DEVELOPMENTAL BIOLOGY
- Frizzled proteins are colonic epithelial receptors for C. difficile toxin B
- (2016) Liang Tao et al. NATURE
- Tissue-specific mutation accumulation in human adult stem cells during life
- (2016) Francis Blokzijl et al. NATURE
- Replication of human noroviruses in stem cell-derived human enteroids
- (2016) K. Ettayebi et al. SCIENCE
- A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
- (2016) Pranjul Shah et al. Nature Communications
- Bacterial Communities: Interactions to Scale
- (2016) Reed M. Stubbendieck et al. Frontiers in Microbiology
- Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A Review in the Theme: Cellular Responses to Hypoxia
- (2015) Leon Zheng et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Modeling rotavirus infection and antiviral therapy using primary intestinal organoids
- (2015) Yuebang Yin et al. ANTIVIRAL RESEARCH
- Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma
- (2015) Tiziana Scanu et al. Cell Host & Microbe
- Interaction of Salmonella enterica Serovar Typhimurium with Intestinal Organoids Derived from Human Induced Pluripotent Stem Cells
- (2015) Jessica L. Forbester et al. INFECTION AND IMMUNITY
- Single-cell messenger RNA sequencing reveals rare intestinal cell types
- (2015) Dominic Grün et al. NATURE
- Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
- (2015) Caroline A. Lindemans et al. NATURE
- Efficient genetic engineering of human intestinal organoids using electroporation
- (2015) Masayuki Fujii et al. Nature Protocols
- Gut biogeography of the bacterial microbiota
- (2015) Gregory P. Donaldson et al. NATURE REVIEWS MICROBIOLOGY
- The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro
- (2014) Massimo Marzorati et al. BMC MICROBIOLOGY
- Cancer Cell Lines for Drug Discovery and Development
- (2014) J. L. Wilding et al. CANCER RESEARCH
- Persistence and Toxin Production by Clostridium difficile within Human Intestinal Organoids Result in Disruption of Epithelial Paracellular Barrier Function
- (2014) Jhansi L. Leslie et al. INFECTION AND IMMUNITY
- Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
- (2014) Kyle W. McCracken et al. NATURE
- Differential Modulation by Akkermansia muciniphila and Faecalibacterium prausnitzii of Host Peripheral Lipid Metabolism and Histone Acetylation in Mouse Gut Organoids
- (2014) S. Lukovac et al. mBio
- Loss of NHE3 alters gut microbiota composition and influences Bacteroides thetaiotaomicron growth
- (2013) Melinda A. Engevik et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Fusobacterium nucleatum Promotes Colorectal Carcinogenesis by Modulating E-Cadherin/β-Catenin Signaling via its FadA Adhesin
- (2013) Mara Roxana Rubinstein et al. Cell Host & Microbe
- Engineering of three-dimensional microenvironments to promote contractile behavior in primary intestinal organoids
- (2013) Rebecca L. DiMarco et al. Integrative Biology
- Toll-like Receptor 4 Is Expressed on Intestinal Stem Cells and Regulates Their Proliferation and Apoptosis via the p53 Up-regulated Modulator of Apoptosis
- (2012) Matthew D. Neal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow
- (2012) Hyun Jung Kim et al. LAB ON A CHIP
- Stem Cell-Derived Human Intestinal Organoids as an Infection Model for Rotaviruses
- (2012) S. R. Finkbeiner et al. mBio
- An ex vivo method for studying mucus formation, properties, and thickness in human colonic biopsies and mouse small and large intestinal explants
- (2011) Jenny K. Gustafsson et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium
- (2011) Toshiro Sato et al. GASTROENTEROLOGY
- Microbial Community Development in a Dynamic Gut Model Is Reproducible, Colon Region Specific, and Selective for Bacteroidetes and Clostridium Cluster IX
- (2010) P. Van den Abbeele et al. APPLIED AND ENVIRONMENTAL MICROBIOLOGY
- Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
- (2010) Jason R. Spence et al. NATURE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search