- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular mechanism of prestin electromotive signal amplification
Authors
Keywords
hearing, cochlear amplification, cryo-EM, protein lipid interaction, prestin, electromotility, intrinsic voltage sensor, membrane protein, outer hair cells, mechanotransduction
Journal
CELL
Volume 184, Issue 18, Pages 4669-4679.e13
Publisher
Elsevier BV
Online
2021-08-13
DOI
10.1016/j.cell.2021.07.034
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- GOLEM: Automated and Robust Cryo-EM-Guided Ligand Docking with Explicit Water Molecules
- (2021) Zhiyu Zhao et al. BIOPHYSICAL JOURNAL
- Prestin amplifies cardiac motor functions
- (2021) Xiao-Dong Zhang et al. Cell Reports
- Complex nonlinear capacitance in outer hair cell macro-patches: effects of membrane tension
- (2020) Joseph Santos-Sacchi et al. Scientific Reports
- Scalable molecular dynamics on CPU and GPU architectures with NAMD
- (2020) James C. Phillips et al. JOURNAL OF CHEMICAL PHYSICS
- Structural insights into the gating mechanism of human SLC26A9 mediated by its C-terminal sequence
- (2020) Ximin Chi et al. Cell Discovery
- Boosting Free-Energy Perturbation Calculations with GPU-Accelerated NAMD
- (2020) Haochuan Chen et al. Journal of Chemical Information and Modeling
- UCSF ChimeraX : Structure visualization for researchers, educators, and developers
- (2020) Eric F. Pettersen et al. PROTEIN SCIENCE
- Cryo-EM structures and functional characterization of murine Slc26a9 reveal mechanism of uncoupled chloride transport
- (2019) Justin D Walter et al. eLife
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
- (2019) Dorothee Liebschner et al. Acta Crystallographica Section D-Structural Biology
- Real-space refinement in PHENIX for cryo-EM and crystallography
- (2018) Pavel V. Afonine et al. Acta Crystallographica Section D-Structural Biology
- Outer Hair Cells and Electromotility
- (2018) Jonathan Ashmore Cold Spring Harbor Perspectives in Medicine
- New tools for automated high-resolution cryo-EM structure determination in RELION-3
- (2018) Jasenko Zivanov et al. eLife
- Relative Binding Free Energy Calculations in Drug Discovery: Recent Advances and Practical Considerations
- (2017) Zoe Cournia et al. Journal of Chemical Information and Modeling
- Structure of the mechanically activated ion channel Piezo1
- (2017) Kei Saotome et al. NATURE
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- Structure-based membrane dome mechanism for Piezo mechanosensitivity
- (2017) Yusong R Guo et al. eLife
- Chloride Anions Regulate Kinetics but Not Voltage-Sensor Q max of the Solute Carrier SLC26a5
- (2016) Joseph Santos-Sacchi et al. BIOPHYSICAL JOURNAL
- The R130S mutation significantly affects the function of prestin, the outer hair cell motor protein
- (2016) Satoe Takahashi et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Biological Nanomotors with a Revolution, Linear, or Rotation Motion Mechanism
- (2016) Peixuan Guo et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- CHARMM36m: an improved force field for folded and intrinsically disordered proteins
- (2016) Jing Huang et al. NATURE METHODS
- Structure of eukaryotic purine/H+ symporter UapA suggests a role for homodimerization in transport activity
- (2016) Yilmaz Alguel et al. Nature Communications
- The STAS domain of mammalian SLC26A5 prestin harbours an anion-binding site
- (2015) G. Lolli et al. BIOCHEMICAL JOURNAL
- Alignment of cryo-EM movies of individual particles by optimization of image translations
- (2015) John L. Rubinstein et al. JOURNAL OF STRUCTURAL BIOLOGY
- Architecture of the mammalian mechanosensitive Piezo1 channel
- (2015) Jingpeng Ge et al. NATURE
- Crystal structure of the anion exchanger domain of human erythrocyte band 3
- (2015) T. Arakawa et al. SCIENCE
- Chloride and Salicylate Influence Prestin-dependent Specific Membrane Capacitance
- (2014) Joseph Santos-Sacchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Screening and large-scale expression of membrane proteins in mammalian cells for structural studies
- (2014) April Goehring et al. Nature Protocols
- Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters
- (2014) Dmitry Gorbunov et al. Nature Communications
- Rapid parameterization of small molecules using the force field toolkit
- (2013) Christopher G. Mayne et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Using collective variables to drive molecular dynamics simulations
- (2013) Giacomo Fiorin et al. MOLECULAR PHYSICS
- Diverse spectrum of rare deafness genes underlies early-childhood hearing loss in Japanese patients: a cross-sectional, multi-center next-generation sequencing study
- (2013) Hideki Mutai et al. Orphanet Journal of Rare Diseases
- Disparities in voltage-sensor charge and electromotility imply slow chloride-driven state transitions in the solute carrier SLC26a5
- (2013) L. Song et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Membrane Cholesterol Strongly Influences Confined Diffusion of Prestin
- (2012) R.I. Kamar et al. BIOPHYSICAL JOURNAL
- The V499G/Y501H Mutation Impairs Fast Motor Kinetics of Prestin and Has Significance for Defining Functional Independence of Individual Prestin Subunits
- (2012) Kazuaki Homma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A motif of eleven amino acids is a structural adaptation that facilitates motor capability of eutherian prestin
- (2012) Xiaodong Tan et al. JOURNAL OF CELL SCIENCE
- Automation of the CHARMM General Force Field (CGenFF) II: Assignment of Bonded Parameters and Partial Atomic Charges
- (2012) K. Vanommeslaeghe et al. Journal of Chemical Information and Modeling
- A Toolkit for the Analysis of Free-Energy Perturbation Calculations
- (2012) Peng Liu et al. Journal of Chemical Theory and Computation
- A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity
- (2011) Thorsten J Schaechinger et al. EMBO JOURNAL
- Improved Treatment of Ligands and Coupling Effects in Empirical Calculation and Rationalization of pKaValues
- (2011) Chresten R. Søndergaard et al. Journal of Chemical Theory and Computation
- PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions
- (2011) Mats H. M. Olsson et al. Journal of Chemical Theory and Computation
- Prestin in HEK cells is an obligate tetramer
- (2011) Richard Hallworth et al. JOURNAL OF NEUROPHYSIOLOGY
- Structure and mechanism of the uracil transporter UraA
- (2011) Feiran Lu et al. NATURE
- Prestin-Driven Cochlear Amplification Is Not Limited by the Outer Hair Cell Membrane Time Constant
- (2011) Stuart L. Johnson et al. NEURON
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Sensitivity of Prestin-Based Membrane Motor to Membrane Thickness
- (2010) Jie Fang et al. BIOPHYSICAL JOURNAL
- Conformational State-Dependent Anion Binding in Prestin: Evidence for Allosteric Modulation
- (2010) Lei Song et al. BIOPHYSICAL JOURNAL
- The ultrastructural distribution of prestin in outer hair cells: a post-embedding immunogold investigation of low-frequency and high-frequency regions of the rat cochlea
- (2010) Shanthini Mahendrasingam et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Evidence That Prestin Has at Least Two Voltage-dependent Steps
- (2010) Kazuaki Homma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types
- (2010) Jeffery B. Klauda et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Functional Reconstitution of an ABC Transporter in Nanodiscs for Use in Electron Paramagnetic Resonance Spectroscopy
- (2010) Frances Joan D. Alvarez et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Prestin's Anion Transport and Voltage-Sensing Capabilities Are Independent
- (2009) Jun-Ping Bai et al. BIOPHYSICAL JOURNAL
- Regulation of the Protein-Conducting Channel by a Bound Ribosome
- (2009) James Gumbart et al. STRUCTURE
- Anion Control of Voltage Sensing by the Motor Protein Prestin in Outer Hair Cells
- (2008) Volodymyr Rybalchenko et al. BIOPHYSICAL JOURNAL
- Cochlear amplification, outer hair cells and prestin
- (2008) Peter Dallos CURRENT OPINION IN NEUROBIOLOGY
- Membrane Composition Modulates Prestin-associated Charge Movement
- (2008) John Sfondouris et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CHARMM-GUI: A web-based graphical user interface for CHARMM
- (2008) Sunhwan Jo et al. JOURNAL OF COMPUTATIONAL CHEMISTRY
- Sensing voltage across lipid membranes
- (2008) Kenton J. Swartz NATURE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More