Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Authors
Keywords
-
Journal
CELL
Volume 184, Issue 13, Pages 3502-3518.e33
Publisher
Elsevier BV
Online
2021-05-27
DOI
10.1016/j.cell.2021.04.037
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation
- (2020) Denis P. Blondin et al. Cell Metabolism
- Opposing Actions of Adrenocorticotropic Hormone and Glucocorticoids on UCP1-Mediated Respiration in Brown Adipocytes
- (2019) Katharina Schnabl et al. Frontiers in Physiology
- The brown adipose tissue glucagon receptor is functional but not essential for control of energy homeostasis in mice
- (2019) Jacqueline L. Beaudry et al. Molecular Metabolism
- Illuminating G-Protein-Coupling Selectivity of GPCRs
- (2019) Asuka Inoue et al. CELL
- Selective activation of Gs signaling in adipocytes causes striking metabolic improvements in mice
- (2019) Lei Wang et al. Molecular Metabolism
- Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis
- (2019) Alexandre Caron et al. Molecular Metabolism
- Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21
- (2019) Bhavani S. Sahu et al. Cell Reports
- Physiological roles of the GIP receptor in murine brown adipose tissue
- (2019) Jacqueline L. Beaudry et al. Molecular Metabolism
- Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
- (2018) Elahu G. Sustarsic et al. Cell Metabolism
- Towards a better understanding of the cannabinoid-related orphan receptors GPR3, GPR6, and GPR12
- (2018) Paula Morales et al. DRUG METABOLISM REVIEWS
- Non-adrenergic control of lipolysis and thermogenesis in adipose tissues
- (2018) Katharina Braun et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Accumulation of succinate controls activation of adipose tissue thermogenesis
- (2018) Evanna L. Mills et al. NATURE
- Intact innervation is essential for diet-induced recruitment of brown adipose tissue
- (2018) Alexander W. Fischer et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation
- (2018) Yongguo Li et al. CELL
- Inhibition of Mevalonate Pathway Prevents Adipocyte Browning in Mice and Men by Affecting Protein Prenylation
- (2018) Miroslav Balaz et al. Cell Metabolism
- Thermal stress induces glycolytic beige fat formation via a myogenic state
- (2018) Yong Chen et al. NATURE
- Adipocyte Expression of SLC19A1 Links DNA Hypermethylation to Adipose Tissue Inflammation and Insulin Resistance
- (2017) Paul Petrus et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Novel Pharmacological Probes Reveal ABHD5 as a Locus of Lipolysis Control in White and Brown Adipocytes
- (2017) Elizabeth A. Rondini et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- The neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis
- (2017) Cheryl Cero et al. Molecular Metabolism
- Characterization of immortalized human brown and white pre-adipocyte cell models from a single donor
- (2017) Lasse K. Markussen et al. PLoS One
- Brown Adipose Tissue Activation Is Linked to Distinct Systemic Effects on Lipid Metabolism in Humans
- (2016) Maria Chondronikola et al. Cell Metabolism
- Role of Brown Fat in Lipoprotein Metabolism and Atherosclerosis
- (2016) Geerte Hoeke et al. CIRCULATION RESEARCH
- Brown adipose tissue as a secretory organ
- (2016) Francesc Villarroya et al. Nature Reviews Endocrinology
- The Gq signalling pathway inhibits brown and beige adipose tissue
- (2016) Katarina Klepac et al. Nature Communications
- Bmp4 Promotes a Brown to White-like Adipocyte Shift
- (2016) Salvatore Modica et al. Cell Reports
- Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis
- (2016) Maria Razzoli et al. Molecular Metabolism
- A Creatine-Driven Substrate Cycle Enhances Energy Expenditure and Thermogenesis in Beige Fat
- (2015) Lawrence Kazak et al. CELL
- Endogenous and Synthetic ABHD5 Ligands Regulate ABHD5-Perilipin Interactions and Lipolysis in Fat and Muscle
- (2015) Matthew A. Sanders et al. Cell Metabolism
- Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist
- (2015) Aaron M. Cypess et al. Cell Metabolism
- PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program
- (2015) Matthew J. Harms et al. GENES & DEVELOPMENT
- The Activation Mechanism of Glycoprotein Hormone Receptors with Implications in the Cause and Therapy of Endocrine Diseases
- (2015) Antje Brüser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brown and beige fat in humans: thermogenic adipocytes that control energy and glucose homeostasis
- (2015) Labros Sidossis et al. JOURNAL OF CLINICAL INVESTIGATION
- Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes
- (2015) Ruidan Xue et al. NATURE MEDICINE
- iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data
- (2015) Jesper Grud Skat Madsen et al. NUCLEIC ACIDS RESEARCH
- Anti-obesity and metabolic efficacy of the β3-adrenergic agonist, CL316243, in mice at thermoneutrality compared to 22°C
- (2015) Cuiying Xiao et al. Obesity
- Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
- (2015) Jimmy F. P. Berbée et al. Nature Communications
- Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue
- (2015) Grzegorz Godlewski et al. Scientific Reports
- RNA-Seq and Mass-Spectrometry-Based Lipidomics Reveal Extensive Changes of Glycerolipid Pathways in Brown Adipose Tissue in Response to Cold
- (2015) Ann-Britt Marcher et al. Cell Reports
- An siRNA-based method for efficient silencing of gene expression in mature brown adipocytes
- (2015) Marie S. Isidor et al. Adipocyte
- IRF4 Is a Key Thermogenic Transcriptional Partner of PGC-1α
- (2014) Xingxing Kong et al. CELL
- What We Talk About When We Talk About Fat
- (2014) Evan D. Rosen et al. CELL
- Brown adipose tissue takes up plasma triglycerides mostly after lipolysis
- (2014) P. Padmini S. J. Khedoe et al. JOURNAL OF LIPID RESEARCH
- Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
- (2014) Thorsten Gnad et al. NATURE
- Whole-Exome Sequencing of 2,000 Danish Individuals and the Role of Rare Coding Variants in Type 2 Diabetes
- (2013) Kirk E. Lohmueller et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Beyond the Sympathetic Tone: The New Brown Fat Activators
- (2013) Francesc Villarroya et al. Cell Metabolism
- A Classical Brown Adipose Tissue mRNA Signature Partly Overlaps with Brite in the Supraclavicular Region of Adult Humans
- (2013) Naja Zenius Jespersen et al. Cell Metabolism
- Cold acclimation recruits human brown fat and increases nonshivering thermogenesis
- (2013) Anouk A.J.J. van der Lans et al. JOURNAL OF CLINICAL INVESTIGATION
- Bi-directional interconversion of brite and white adipocytes
- (2013) Matthias Rosenwald et al. NATURE CELL BIOLOGY
- Development of small-molecule inhibitors targeting adipose triglyceride lipase
- (2013) Nicole Mayer et al. Nature Chemical Biology
- Brown and beige fat: development, function and therapeutic potential
- (2013) Matthew Harms et al. NATURE MEDICINE
- miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit
- (2013) Yong Chen et al. Nature Communications
- UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic
- (2013) Irina G. Shabalina et al. Cell Reports
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
- (2012) Jun Wu et al. CELL
- FAT SIGNALS - Lipases and Lipolysis in Lipid Metabolism and Signaling
- (2012) Rudolf Zechner et al. Cell Metabolism
- Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity
- (2012) E. Arner et al. DIABETES
- Lipolytic Products Activate Peroxisome Proliferator-activated Receptor (PPAR) α and δ in Brown Adipocytes to Match Fatty Acid Oxidation with Supply
- (2012) Emilio P. Mottillo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Brown adipose tissue activity controls triglyceride clearance
- (2011) Alexander Bartelt et al. NATURE MEDICINE
- An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81
- (2010) Kashan Ahmed et al. Cell Metabolism
- Sympathetic and sensory innervation of brown adipose tissue
- (2010) T J Bartness et al. INTERNATIONAL JOURNAL OF OBESITY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- The N-terminal domain of GPR61, an orphan G-protein-coupled receptor, is essential for its constitutive activity
- (2008) Masaru Toyooka et al. JOURNAL OF NEUROSCIENCE RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search