Cancer Grade Model: a multi-gene machine learning-based risk classification for improving prognosis in breast cancer

Clinically high-risk breast cancer displays markedly discordant molecular risk predictions between the MammaPrint and EndoPredict tests

(2020) Stephan Wenzel Jahn et al.   BRITISH JOURNAL OF CANCER

Machine learning-based lifetime breast cancer risk reclassification compared with the BOADICEA model: impact on screening recommendations

(2020) Chang Ming et al.   BRITISH JOURNAL OF CANCER

Merging microarray studies to identify a common gene expression signature to several structural heart diseases

(2020) Olga Fajarda et al.   BioData Mining

Beyond Chemotherapies: Recent Strategies in Breast Cancer Treatment

(2020) Arthur Foulon et al.   Cancers

ERα upregulates the expression of long non-coding RNA LINC00472 which suppresses the phosphorylation of NF-κB in breast cancer

(2019) Zhanwei Wang et al.   BREAST CANCER RESEARCH AND TREATMENT

Prognostic models for breast cancer: a systematic review

(2019) Minh Tung Phung et al.   BMC CANCER

Avoiding over- and undertreatment in patients with resected node-positive breast cancer with the use of gene expression signatures: are we there yet?

(2019) A Matikas et al.   ANNALS OF ONCOLOGY

CDC20 associated with cancer metastasis and novel mushroom‑derived CDC20 inhibitors with antimetastatic activity

(2019) Shujie Cheng et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Early breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†

(2019) F Cardoso et al.   ANNALS OF ONCOLOGY

Machine learning for tissue diagnostics in oncology: brave new world

(2019) Niels Halama   BRITISH JOURNAL OF CANCER

Cancer therapeutics using survivin BIRC5 as a target: what can we do after over two decades of study?

(2019) Fengzhi Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Breast cancer

(2019) Nadia Harbeck et al.   Nature Reviews Disease Primers

A clinical evaluation of treatments that target cell cycle machinery in breast cancer

(2019) Palma Fedele et al.   EXPERT OPINION ON PHARMACOTHERAPY

The reactome pathway knowledgebase

(2019) Bijay Jassal et al.   NUCLEIC ACIDS RESEARCH

Downregulation of BIRC5 inhibits the migration and invasion of esophageal cancer cells by interacting with the PI3K/Akt signaling pathway

(2018) Xiaobin Shang et al.   Oncology Letters

Targeting the cell cycle in breast cancer: towards the next phase

(2018) KL Thu et al.   CELL CYCLE

Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer

(2018) Miaomiao Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer

(2018) Peter Schmid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nuclear functions of NME proteins

(2017) Gemma S Puts et al.   LABORATORY INVESTIGATION

Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation

(2017) Mark Robson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Voltage-gated calcium channels: Novel targets for cancer therapy

(2017) Nam Nhut Phan et al.   Oncology Letters

Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline

(2016) Lyndsay N. Harris et al.   JOURNAL OF CLINICAL ONCOLOGY

ReactomePA: an R/Bioconductor package for reactome pathway analysis and visualization

(2016) Guangchuang Yu et al.   Molecular BioSystems

Upregulation of E2F8 promotes cell proliferation and tumorigenicity in breast cancer by modulating G1/S phase transition

(2016) Liping Ye et al.   Oncotarget

AurkA controls self-renewal of breast cancer-initiating cells promoting wnt3a stabilization through suppression of miR-128

(2016) V. Eterno et al.   Scientific Reports

Genefu: an R/Bioconductor package for computation of gene expression-based signatures in breast cancer

(2015) Deena M. A. Gendoo et al.   BIOINFORMATICS

Phase II, multicenter, open-label, randomized study of YM155 plus docetaxel as first-line treatment in patients with HER2-negative metastatic breast cancer

(2014) Michael R. Clemens et al.   BREAST CANCER RESEARCH AND TREATMENT

Histological grade concordance between diagnostic core biopsy and corresponding surgical specimen in HR-positive/HER2-negative breast carcinoma

(2014) C Daveau et al.   BRITISH JOURNAL OF CANCER

Genomic Grade Index predicts postoperative clinical outcome of GIST

(2012) F Bertucci et al.   BRITISH JOURNAL OF CANCER

Immunotherapeutic benefit of α-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients

(2012) Hidekazu Kameshima et al.   CANCER SCIENCE

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

PTTG1Oncogene Promotes Tumor Malignancy via Epithelial to Mesenchymal Transition and Expansion of Cancer Stem Cell Population

(2012) Chang-Hwan Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors

(2011) Martin Filipits et al.   CLINICAL CANCER RESEARCH

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Phase I study of LY2181308, an antisense oligonucleotide against survivin, in patients with advanced solid tumors

(2010) M. Tanioka et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2009

(2009) A. Goldhirsch et al.   ANNALS OF ONCOLOGY

Supervised Risk Predictor of Breast Cancer Based on Intrinsic Subtypes

(2009) Joel S. Parker et al.   JOURNAL OF CLINICAL ONCOLOGY

Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial

(2009) Kathy S Albain et al.   LANCET ONCOLOGY

Gene-Expression Signatures in Breast Cancer

(2009) Christos Sotiriou et al.   NEW ENGLAND JOURNAL OF MEDICINE