Fuxin Granules ameliorate diabetic nephropathy in db/db mice through TGF-β1/Smad and VEGF/VEGFR2 signaling pathways

Uncovering the Mechanism of Astragalus membranaceus in the Treatment of Diabetic Nephropathy Based on Network Pharmacology

(2020) Ming-Fei Guo et al.   Journal of Diabetes Research

Revisiting Experimental Models of Diabetic Nephropathy

(2020) Anna Giralt-López et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Relieving Sore Throat Formula Exerts a Therapeutic Effect on Pharyngitis through Immunoregulation and NF-κB Pathway

(2020) Yushi Ding et al.   MEDIATORS OF INFLAMMATION

A New Oleanane Type Saponin from the Aerial Parts of Nigella sativa with Anti-Oxidant and Anti-Diabetic Potential

(2020) Amna Parveen et al.   MOLECULES

Polydatin attenuates renal fibrosis in diabetic mice through regulating the Cx32-Nox4 signaling pathway

(2020) Zhi-quan Chen et al.   ACTA PHARMACOLOGICA SINICA

Hederagenin Attenuates Cerebral Ischaemia/Reperfusion Injury by Regulating MLK3 Signalling

(2020) Hailong Yu et al.   Frontiers in Pharmacology

Anticancer and antimicrobial compounds from Croton caudatus Gieseler and Eurya acuminata DC: Two edible plants used in the traditional medicine of the Kuki tribes

(2020) Neipihoi et al.   NATURAL PRODUCT RESEARCH

Study on the Mechanisms of Banxia Xiexin Decoction in Treating Diabetic Gastroparesis Based on Network Pharmacology

(2020) Tingchao Wu et al.   Interdisciplinary Sciences-Computational Life Sciences

Zhile Capsule Exerts Antidepressant-Like Effects through Upregulation of the BDNF Signaling Pathway and Neuroprotection

(2019) Jiawei Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Formononetin Antagonizes the Interleukin-1β-Induced Catabolic Effects Through Suppressing Inflammation in Primary Rat Chondrocytes

(2019) In-A Cho et al.   INFLAMMATION

Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases

(2019) Hassan Ashktorab et al.   Nutrients

Radix et Rhizoma Ginseng chemoprevents both initiation and promotion of cutaneous carcinoma by enhancing cell-mediated immunity and maintaining redox homeostasis

(2019) Suyun Yu et al.   Journal of Ginseng Research

Urinary Cell Adhesion Molecule 1 Is a Novel Biomarker That Links Tubulointerstitial Damage to Glomerular Filtration Rates in Chronic Kidney Disease

(2019) Man Hagiyama et al.   Frontiers in Cell and Developmental Biology

Magnesium lithospermate B improves the gut microbiome and bile acid metabolic profiles in a mouse model of diabetic nephropathy

(2018) Jing Zhao et al.   ACTA PHARMACOLOGICA SINICA

Central role of dysregulation of TGF-β/Smad in CKD progression and potential targets of its treatment

(2018) Lin Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

The co-formulation of insulin degludec and insulin aspart lowers fasting plasma glucose and rates of confirmed and nocturnal hypoglycaemia, independent of baseline glycated haemoglobin levels, disease duration or body mass index: A pooled meta-analysis of

(2018) Martin Haluzík et al.   DIABETES OBESITY & METABOLISM

Formononetin Treatment in Type 2 Diabetic Rats Reduces Insulin Resistance and Hyperglycemia

(2018) Manisha J. Oza et al.   Frontiers in Pharmacology

Decreased Expression of Vascular Endothelial Growth Factor Receptor 1 Contributes to the Pathogenesis of Hereditary Hemorrhagic Telangiectasia Type 2

(2018) Jérémy H. Thalgott et al.   CIRCULATION

Amelioration of diabetic nephropathy in db/db mice treated with tibetan medicine formula Siwei Jianghuang Decoction Powder extract

(2018) Xianrong Lai et al.   Scientific Reports

Network-based Approaches in Pharmacology

(2017) Baptiste Boezio et al.   Molecular Informatics

Tianfoshen oral liquid: a CFDA approved clinical traditional Chinese medicine, normalizes major cellular pathways disordered during colorectal carcinogenesis

(2017) Siliang Wang et al.   Oncotarget

Stigmasterol prevents glucolipotoxicity induced defects in glucose-stimulated insulin secretion

(2017) Meliza G. Ward et al.   Scientific Reports

Systemic Associations with Residual Subretinal Fluid after Ranibizumab in Diabetic Macular Edema

(2017) Meng-Ju Tsai et al.   Journal of Ophthalmology

System Pharmacology-Based Dissection of the Synergistic Mechanism of Huangqi and Huanglian for Diabetes Mellitus

(2017) Shi-Jun Yue et al.   Frontiers in Pharmacology

Are the Therapeutic Effects of Huangqi (Astragalus membranaceus) on Diabetic Nephropathy Correlated with Its Regulation of Macrophage iNOS Activity?

(2017) Hui Liao et al.   Journal of Immunology Research

Resveratrol ameliorates myocardial fibrosis by inhibiting ROS/ERK/TGF-β/periostin pathway in STZ-induced diabetic mice

(2016) Han Wu et al.   BMC Cardiovascular Disorders

An Update on the Use of Animal Models in Diabetic Nephropathy Research

(2016) Boris Betz et al.   Current Diabetes Reports

Systems Pharmacology: A Unified Framework for Prediction of Drug-Target Interactions

(2016) Duc-Hau Le et al.   CURRENT PHARMACEUTICAL DESIGN

A novel systems pharmacology platform to dissect action mechanisms of traditional Chinese medicines for bovine viral diarrhea disease

(2016) Chunli Zheng et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Synthetic stigmasterol derivatives inhibit capillary tube formation, herpetic corneal neovascularization and tumor induced angiogenesis

(2016) Flavia M. Michelini et al.   STEROIDS

Association of Chemerin and Vascular Endothelial Growth Factor (VEGF) with Diabetic Nephropathy

(2016) Shuhua Lin et al.   MEDICAL SCIENCE MONITOR

Melissa officinalis Protects against Doxorubicin-Induced Cardiotoxicity in Rats and Potentiates Its Anticancer Activity on MCF-7 Cells

(2016) Alaaeldin Ahmed Hamza et al.   PLoS One

CytoNCA: A cytoscape plugin for centrality analysis and evaluation of protein interaction networks

(2015) Yu Tang et al.   BIOSYSTEMS

Attention to Background Strain Is Essential for Metabolic Research: C57BL/6 and the International Knockout Mouse Consortium

(2015) Danielle A. Fontaine et al.   DIABETES

Aspectos celulares y moleculares de la nefropatía diabética, rol del VEGF-A

(2015) Katherine Carranza et al.   NEFROLOGIA

Molecular mechanisms of diabetic kidney disease

(2014) Kimberly Reidy et al.   JOURNAL OF CLINICAL INVESTIGATION

Dahuang Fuzi Decoction ameliorates tubular epithelial apoptosis and renal damage via inhibiting TGF-β1-JNK signaling pathway activation in vivo

(2014) Yue Tu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling

(2011) Hariom Yadav et al.   Cell Metabolism

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Mouse Models of Diabetic Nephropathy

(2009) F. C. Brosius et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Different roles for TGF-β and VEGF in the pathogenesis of the cardinal features of diabetic nephropathy

(2008) Fuad N. Ziyadeh   DIABETES RESEARCH AND CLINICAL PRACTICE