Are the Therapeutic Effects of Huangqi (Astragalus membranaceus) on Diabetic Nephropathy Correlated with Its Regulation of Macrophage iNOS Activity?

The pattern recognition receptor, Mincle, is essential for maintaining the M1 macrophage phenotype in acute renal inflammation

(2017) Lin L. Lv et al.   KIDNEY INTERNATIONAL

Astragaloside IV attenuates cognitive impairments induced by transient cerebral ischemia and reperfusion in mice via anti-inflammatory mechanisms

(2017) Min Li et al.   NEUROSCIENCE LETTERS

Urinary podocyte-associated mRNA levels correlate with proximal tubule dysfunction in early diabetic nephropathy of type 2 diabetes mellitus

(2017) Ligia Petrica et al.   Diabetology & Metabolic Syndrome

Astragalus polysaccharides exerts immunomodulatory effects via TLR4-mediated MyD88-dependent signaling pathway in vitro and in vivo

(2017) Lijing Zhou et al.   Scientific Reports

Astragalus saponins Inhibits Lipopolysaccharide-Induced Inflammation in Mouse Macrophages

(2016) Yue Wang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

Comparative studies on the immunoregulatory effects of three polysaccharides using high content imaging system

(2016) Xiaocheng Lv et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

TLR-4 may mediate signaling pathways of Astragalus polysaccharide RAP induced cytokine expression of RAW264.7 cells

(2016) Wei Wei et al.   JOURNAL OF ETHNOPHARMACOLOGY

Trends in Chronic Kidney Disease in China

(2016) Luxia Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ameliorative effects of pentoxifylline on NOS induced by diabetes in rat kidney

(2016) Mehmet Fatih Sönmez et al.   RENAL FAILURE

Astragaloside IV attenuates proteinuria in streptozotocin-induced diabetic nephropathy via the inhibition of endoplasmic reticulum stress

(2015) Zeng Si Wang et al.   BMC Nephrology

Astragalus membranaceus Injection combined with conventional treatment for viral myocarditis: A systematic review of randomized controlled trials

(2014) Yuan-lin Piao et al.   Chinese Journal of Integrative Medicine

Inhibition of Macrophage Migration Inhibitory Factor Reduces Diabetic Nephropathy in Type II Diabetes Mice

(2014) Zhigang Wang et al.   INFLAMMATION

Pharmacokinetics and hepatic uptake of gliquidone affected by Huangqi injection

(2013) Fan Zhang et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

NF-κB Inhibitory Activity of Sucrose Fatty Acid Esters and Related Constituents from Astragalus membranaceus

(2013) Wei Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anti-Inflammatory Cycloartane-Type Saponins of Astragalus membranaceus

(2013) Dae-Young Lee et al.   MOLECULES

The role of heparanase and the endothelial glycocalyx in the development of proteinuria

(2013) Marjolein Garsen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Clinical Value of Huangqi Injection in the Treatment of Leucopenia: A Meta-Analysis of Clinical Controlled Trials

(2013) Changsong Zhang et al.   PLoS One

Isolation of Anti-Inflammatory Fractions and Compounds from the Root ofAstragalus membranaceus

(2012) Patrick Kwok-Kin Lai et al.   PHYTOTHERAPY RESEARCH

Characterization of polysaccharide from Astragalus radix as the macrophage stimulator

(2011) Lu-Hang Zhao et al.   CELLULAR IMMUNOLOGY

The emerging role of NO and IGF-1 in early renal hypertrophy in STZ-induced diabetic rats

(2011) Nomy Levin-Iaina et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

New Isoflavonoid Glycosides and Related Constituents from Astragali Radix (Astragalus membranaceus) and Their Inhibitory Activity on Nitric Oxide Production

(2011) Li-Jie Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Endotoxin Tolerance Represents a Distinctive State of Alternative Polarization (M2) in Human Mononuclear Cells

(2011) O. M. Pena et al.   JOURNAL OF IMMUNOLOGY

Distinct Macrophage Phenotypes Contribute to Kidney Injury and Repair

(2011) S. Lee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Meta-analysis of the clinical value of Astragalus membranaceus in diabetic nephropathy

(2010) Mingxin Li et al.   JOURNAL OF ETHNOPHARMACOLOGY

The Genetic Inactivation of Inducible Nitric Oxide Synthase (iNOS) Intensifies Fibrosis and Oxidative Stress in the Penile Corpora Cavernosa in Type 1 Diabetes

(2010) Monica G. Ferrini et al.   Journal of Sexual Medicine

The production of nitric oxide and prostaglandin E2 in peritoneal macrophages is inhibited by Andrographis paniculata, Angelica sinensis and Morus alba ethyl acetate fractions

(2008) Wen-Wan Chao et al.   JOURNAL OF ETHNOPHARMACOLOGY

Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk

(2007) Minsook Ryu et al.   JOURNAL OF ETHNOPHARMACOLOGY