Fast numerical optimization for genome sequencing data in population biobanks

Genetics of 35 blood and urine biomarkers in the UK Biobank

(2021) Nasa Sinnott-Armstrong et al.   NATURE GENETICS

Fast Lasso method for large-scale and ultrahigh-dimensional Cox model with applications to UK Biobank

(2020) Ruilin Li et al.   BIOSTATISTICS

A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank

(2020) Junyang Qian et al.   PLoS Genetics

LDpred2: better, faster, stronger

(2020) Florian Privé et al.   BIOINFORMATICS

Polygenic prediction via Bayesian regression and continuous shrinkage priors

(2019) Tian Ge et al.   Nature Communications

Phenome-wide Burden of Copy-Number Variation in the UK Biobank

(2019) Matthew Aguirre et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Improved polygenic prediction by Bayesian multiple regression on summary statistics

(2019) Luke R. Lloyd-Jones et al.   Nature Communications

Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr

(2018) Florian Privé et al.   BIOINFORMATICS

Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study

(2018) Christopher DeBoever et al.   Nature Communications

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Regularization Paths for Generalized Linear Models via Coordinate Descent

(2015) Jerome Friedman et al.   Journal of Statistical Software

Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent

(2015) Noah Simon et al.   Journal of Statistical Software

A Fast Iterative Shrinkage-Thresholding Algorithm for Linear Inverse Problems

(2009) Amir Beck et al.   SIAM Journal on Imaging Sciences