A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

(2019) Yosuke Tanigawa et al.   Nature Communications

Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr

(2018) Florian Privé et al.   BIOINFORMATICS

Signatures of negative selection in the genetic architecture of human complex traits

(2018) Jian Zeng et al.   NATURE GENETICS

Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study

(2018) Christopher DeBoever et al.   Nature Communications

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Rare and low-frequency coding variants alter human adult height

(2017) Eirini Marouli et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

(2015) Jian Yang et al.   NATURE GENETICS

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Inference of the Genetic Architecture Underlying BMI and Height with the Use of 20,240 Sibling Pairs

(2013) Gibran Hemani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Using Extended Genealogy to Estimate Components of Heritability for 23 Quantitative and Dichotomous Traits

(2013) Noah Zaitlen et al.   PLoS Genetics

Coordinate descent algorithms for nonconvex penalized regression, with applications to biological feature selection

(2011) Patrick Breheny et al.   Annals of Applied Statistics

From Galton to GWAS: quantitative genetics of human height

(2011) PETER M. VISSCHER et al.   Genetics Research

Dual Averaging for Distributed Optimization: Convergence Analysis and Network Scaling

(2011) J. C. Duchi et al.   IEEE TRANSACTIONS ON AUTOMATIC CONTROL

Strong rules for discarding predictors in lasso-type problems

(2011) Robert Tibshirani et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Simultaneous analysis of Lasso and Dantzig selector

(2009) Peter J. Bickel et al.   ANNALS OF STATISTICS

Genome-wide association analysis by lasso penalized logistic regression

(2009) Tong Tong Wu et al.   BIOINFORMATICS

MapReduce

(2008) Jeffrey Dean et al.   COMMUNICATIONS OF THE ACM

Sure independence screening for ultrahigh dimensional feature space

(2008) Jianqing Fan et al.   JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY