LncRNA LncHrt preserves cardiac metabolic homeostasis and heart function by modulating the LKB1-AMPK signaling pathway

Insight on Transcriptional Regulation of the Energy Sensing AMPK and Biosynthetic mTOR Pathway Genes

(2020) Abitha Sukumaran et al.   Frontiers in Cell and Developmental Biology

Long noncoding RNA Cfast regulates cardiac fibrosis

(2020) Feng Zhang et al.   Molecular Therapy-Nucleic Acids

Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction

(2019) Feng Gao et al.   Nature Communications

Inactivated AMPK-α2 promotes the progression of diabetic brain damage by Cdk5 phosphorylation at Thr485 site

(2019) Yan Li et al.   BIOCHIMIE

Transplanted Mesenchymal Stem Cells Reduce Autophagic Flux in Infarcted Hearts via the Exosomal Transfer of mir-125b

(2018) Changchen Xiao et al.   CIRCULATION RESEARCH

Metabolic Coordination of Physiological and Pathological Cardiac Remodeling

(2018) Andrew A. Gibb et al.   CIRCULATION RESEARCH

SIRT2 deacetylase represses NFAT transcription factor to maintain cardiac homeostasis

(2018) Mohsen Sarikhani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Long Noncoding RNA CAREL Controls Cardiac Regeneration

(2018) Benzhi Cai et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

AMP kinase promotes glioblastoma bioenergetics and tumour growth

(2018) Rishi Raj Chhipa et al.   NATURE CELL BIOLOGY

Golgi Fragmentation in Human Patients with Chronic Atrial Fibrillation: A New Aspect of Remodeling

(2018) Luisa Jungk et al.   THORACIC AND CARDIOVASCULAR SURGEON

Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein

(2018) Hitoshi Watanabe et al.   Nature Communications

Myocardial infarction is sufficient to increase GLP-1 secretion, leading to improved left ventricular contractility and mitochondrial respiratory capacity

(2018) Sebastian Diebold et al.   DIABETES OBESITY & METABOLISM

LncRNA HOTAIR functions as a competing endogenous RNA to upregulate SIRT1 by sponging miR-34a in diabetic cardiomyopathy

(2018) Lu Gao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes

(2017) Vera Lemos et al.   HUMAN MOLECULAR GENETICS

Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015

(2017) Gregory A. Roth et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy

(2017) Jerry R. Mendell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Respiratory Muscle Training Improves Diaphragm Citrate Synthase Activity and Hemodynamic Function in Rats with Heart Failure

(2017) Rodrigo Boemo Jaenisch et al.   Revista Brasileira de Cirurgia Cardiovascular

The long noncoding RNA Wisper controls cardiac fibrosis and remodeling

(2017) Rudi Micheletti et al.   Science Translational Medicine

Remodeling pathway control of mitochondrial respiratory capacity by temperature in mouse heart: electron flow through the Q-junction in permeabilized fibers

(2017) Hélène Lemieux et al.   Scientific Reports

Inhibition of CDK5 Alleviates the Cardiac Phenotypes in Timothy Syndrome

(2017) LouJin Song et al.   Stem Cell Reports

Respiratory Muscle Training Improves Diaphragm Citrate Synthase Activity and Hemodynamic Function in Rats with Heart Failure

(2017) Rodrigo Boemo Jaenisch et al.   BRAZILIAN JOURNAL OF CARDIOVASCULAR SURGERY

Functional genetic variants within the SIRT2 gene promoter in acute myocardial infarction

(2017) Wentao Yang et al.   PLoS One

Reduced mitochondrial respiration in the ischemic as well as in the remote nonischemic region in postmyocardial infarction remodeling

(2016) Diogo T. Galan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Long non-coding RNAs link extracellular matrix gene expression to ischemic cardiomyopathy

(2016) Zhan-Peng Huang et al.   CARDIOVASCULAR RESEARCH

Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis

(2016) Xinjian Li et al.   MOLECULAR CELL

The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy

(2016) Zhihua Wang et al.   NATURE MEDICINE

Cardiac Repair after Myocardial Infarction

(2016) Eva van Rooij   NEW ENGLAND JOURNAL OF MEDICINE

Long noncoding RNA Chast promotes cardiac remodeling

(2016) Janika Viereck et al.   Science Translational Medicine

Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development

(2015) L. Kurian et al.   CIRCULATION

IDH2 deficiency promotes mitochondrial dysfunction and cardiac hypertrophy in mice

(2015) Hyeong Jun Ku et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis

(2015) Zhan-Peng Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Trbp regulates heart function through microRNA-mediated Sox6 repression

(2015) Jian Ding et al.   NATURE GENETICS

Citrate Synthase Is a Novel In Vivo Matrix Metalloproteinase-9 Substrate That Regulates Mitochondrial Function in the Postmyocardial Infarction Left Ventricle

(2014) Lisandra E. de Castro Brás et al.   ANTIOXIDANTS & REDOX SIGNALING

LincRNA-p21 Regulates Neointima Formation, Vascular Smooth Muscle Cell Proliferation, Apoptosis, and Atherosclerosis by Enhancing p53 Activity

(2014) Gengze Wu et al.   CIRCULATION

Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs

(2014) S. Ounzain et al.   EUROPEAN HEART JOURNAL

Cardiovascular remodelling in coronary artery disease and heart failure

(2014) Gerd Heusch et al.   LANCET

Cardiac Metabolism and its Interactions With Contraction, Growth, and Survival of Cardiomyocytes

(2013) Stephen C. Kolwicz et al.   CIRCULATION RESEARCH

An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins

(2013) Kathrin Leppek et al.   NUCLEIC ACIDS RESEARCH

CPAT: Coding-Potential Assessment Tool using an alignment-free logistic regression model

(2013) Liguo Wang et al.   NUCLEIC ACIDS RESEARCH

Normalizing the metabolic phenotype after myocardial infarction: Impact of subchronic high fat feeding

(2012) Jessica M. Berthiaume et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Glucose metabolism and cardiac hypertrophy

(2011) S. C. Kolwicz et al.   CARDIOVASCULAR RESEARCH

Omega-3 Fatty Acids Prevent Pressure Overload–Induced Cardiac Fibrosis Through Activation of Cyclic GMP/Protein Kinase G Signaling in Cardiac Fibroblasts

(2011) Jinghai Chen et al.   CIRCULATION

Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart

(2011) Hélène Lemieux et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A small molecule AMPK activator protects the heart against ischemia–reperfusion injury

(2011) Agnes S. Kim et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Structure of mammalian AMPK and its regulation by ADP

(2011) Bing Xiao et al.   NATURE

Interdependence of AMPK and SIRT1 for Metabolic Adaptation to Fasting and Exercise in Skeletal Muscle

(2010) Carles Cantó et al.   Cell Metabolism

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Remodelação ventricular pós-infarto do miocárdio: conceitos e implicações clínicas

(2009) Leonardo A. M. Zornoff et al.   Arquivos Brasileiros de Cardiologia

Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction

(2009) Sandra Sena et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Energy metabolism in heart failure and remodelling

(2008) J. S. Ingwall   CARDIOVASCULAR RESEARCH

Activation of AMP-Activated Protein Kinase by Metformin Improves Left Ventricular Function and Survival in Heart Failure

(2008) Susheel Gundewar et al.   CIRCULATION RESEARCH

SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1

(2008) Fan Lan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility

(2008) Ruwin Pandithage et al.   JOURNAL OF CELL BIOLOGY