The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy

The H19 long noncoding RNA is a novel negative regulator of cardiomyocyte hypertrophy

(2016) Lantao Liu et al.   CARDIOVASCULAR RESEARCH

Long noncoding RNA Chast promotes cardiac remodeling

(2016) Janika Viereck et al.   Science Translational Medicine

Pathological Left Ventricular Hypertrophy and Stem Cells: Current Evidence and New Perspectives

(2016) Maria E. Marketou et al.   Stem Cells International

Long Non-Coding RNA Malat-1 Is Dispensable during Pressure Overload-Induced Cardiac Remodeling and Failure in Mice

(2016) Tim Peters et al.   PLoS One

Long Non-Coding RNA-ROR Mediates the Reprogramming in Cardiac Hypertrophy

(2016) Feng Jiang et al.   PLoS One

Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy

(2015) Pankaj Shende et al.   CARDIOVASCULAR RESEARCH

Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development

(2015) L. Kurian et al.   CIRCULATION

Dawn of The Epi-LncRNAs: New Path from Myheart

(2015) Z. Wang et al.   CIRCULATION RESEARCH

The histone demethylase PHF8 represses cardiac hypertrophy upon pressure overload

(2015) Xiaoqian Liu et al.   EXPERIMENTAL CELL RESEARCH

The alteration of protein prenylation induces cardiomyocyte hypertrophy through Rheb-mTORC1 signalling and leads to chronic heart failure

(2015) Na Xu et al.   JOURNAL OF PATHOLOGY

Central role of SIAH inhibition in DCC-dependent cardioprotection provoked by netrin-1/NO

(2015) Qiang Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK inhibits cardiac hypertrophy by promoting autophagy via mTORC1

(2014) Yanh Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Regulation of histone methylation by noncoding RNAs

(2014) Richard I. Joh et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The Long Noncoding RNA CHRF Regulates Cardiac Hypertrophy by Targeting miR-489

(2014) Kun Wang et al.   CIRCULATION RESEARCH

Circulating Long Noncoding RNA, LIPCAR, Predicts Survival in Patients With Heart Failure

(2014) Regalla Kumarswamy et al.   CIRCULATION RESEARCH

Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs

(2014) S. Ounzain et al.   EUROPEAN HEART JOURNAL

Interferon Regulatory Factor 7 Functions as a Novel Negative Regulator of Pathological Cardiac Hypertrophy

(2014) Ding-Sheng Jiang et al.   HYPERTENSION

Mesenchymal–endothelial transition contributes to cardiac neovascularization

(2014) Eric Ubil et al.   NATURE

A long noncoding RNA protects the heart from pathological hypertrophy

(2014) Pei Han et al.   NATURE

Epigenetic Switch at Atp2a2 and Myh7 Gene Promoters in Pressure Overload-Induced Heart Failure

(2014) Tiziana Angrisano et al.   PLoS One

Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs

(2014) S. J. Matkovich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-214 provokes cardiac hypertrophy via repression of EZH2

(2013) Tao Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Binding Interactions between Long Noncoding RNA HOTAIR and PRC2 Proteins

(2013) Liang Wu et al.   BIOCHEMISTRY

One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering

(2013) Haoyi Wang et al.   CELL

Braveheart, a Long Noncoding RNA Required for Cardiovascular Lineage Commitment

(2013) Carla A. Klattenhoff et al.   CELL

The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse

(2013) Phillip Grote et al.   DEVELOPMENTAL CELL

The Imprinted H19 LncRNA Antagonizes Let-7 MicroRNAs

(2013) Amanda N. Kallen et al.   MOLECULAR CELL

An optimized streptavidin-binding RNA aptamer for purification of ribonucleoprotein complexes identifies novel ARE-binding proteins

(2013) Kathrin Leppek et al.   NUCLEIC ACIDS RESEARCH

Pfam: the protein families database

(2013) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

The Long Noncoding RNA HOTAIR Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma Cells via downregualtion of p21WAF1/CIP1 Expression

(2013) Zhili Liu et al.   PLoS One

Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy

(2013) R. Papait et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H19 lncRNA controls gene expression of the Imprinted Gene Network by recruiting MBD1

(2013) P. Monnier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted Disruption of Hotair Leads to Homeotic Transformation and Gene Derepression

(2013) Lingjie Li et al.   Cell Reports

NetWalker: a contextual network analysis tool for functional genomics

(2012) Kakajan Komurov et al.   BMC GENOMICS

Transcriptional Regulation of the Fetal Cardiac Gene Program

(2012) Koichiro Kuwahara et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Hypertrophic cardiomyopathy

(2012) Barry J Maron et al.   LANCET

Unknown

(2012) Valentina Sala et al.   MOLECULAR MEDICINE

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis

(2012) Paul Delgado-Olguín et al.   NATURE GENETICS

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Characterization of Sucrose transporter alleles and their association with seed yield-related traits in Brassica napus L

(2011) Fupeng Li et al.   BMC PLANT BIOLOGY

Cardiac Raptor Ablation Impairs Adaptive Hypertrophy, Alters Metabolic Gene Expression, and Causes Heart Failure in Mice

(2011) Pankaj Shende et al.   CIRCULATION

Analysis of Transcriptome Complexity Through RNA Sequencing in Normal and Failing Murine Hearts

(2011) Jae-Hyung Lee et al.   CIRCULATION RESEARCH

Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

(2011) M. N. Cabili et al.   GENES & DEVELOPMENT

Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways

(2011) Soojeong Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes

(2011) Patima Sdek et al.   JOURNAL OF CELL BIOLOGY

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions

(2011) Ci Chu et al.   MOLECULAR CELL

A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression

(2011) Kevin C. Wang et al.   NATURE

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

(2011) Matthew D. Young et al.   NUCLEIC ACIDS RESEARCH

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis

(2011) L. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR attenuates the inflammatory response in cardiomyocytes and prevents cardiac dysfunction in pathological hypertrophy

(2010) Xiaoxiao Song et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Reporter-Based Isolation of Induced Pluripotent Stem Cell– and Embryonic Stem Cell–Derived Cardiac Progenitors Reveals Limited Gene Expression Variance

(2010) Linda W. van Laake et al.   CIRCULATION RESEARCH

Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

(2010) S. Kaneko et al.   GENES & DEVELOPMENT

Compensatory hypertrophy induced by ventricular cardiomyocyte-specific COX-2 expression in mice

(2010) John M. Streicher et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk

(2010) Christin E. Burd et al.   PLoS Genetics

Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells

(2009) Gang Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

Loss of Bmx Nonreceptor Tyrosine Kinase Prevents Pressure Overload–Induced Cardiac Hypertrophy

(2008) Scherise A. Mitchell-Jordan et al.   CIRCULATION RESEARCH

Genome-wide histone methylation profile for heart failure

(2008) Ruri Kaneda et al.   GENES TO CELLS

HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy

(2008) F. Friedrichs et al.   GENOME RESEARCH

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE