High-Fidelity and Simultaneous Sensing of Endogenous Mutant and Wild p53 Proteins for Precise Cancer Diagnosis and Drug Screening

ESSENCE – A rapid, shear-enhanced, flow-through, capacitive electrochemical platform for rapid detection of biomolecules

(2021) Yu-Hsuan Cheng et al.   BIOSENSORS & BIOELECTRONICS

Loss of wild-type p53 promotes mutant p53-driven metastasis through acquisition of survival and tumor-initiating properties

(2020) Mizuho Nakayama et al.   Nature Communications

A Protein in the Yeast Saccharomyces cerevisiae Presents DNA Binding Homology to the p53 Checkpoint Protein and Tumor Suppressor

(2020) Kanwal Farooqi et al.   Biomolecules

Ultrasensitive detection of anti-p53 autoantibodies based on nanomagnetic capture and separation with fluorescent sensing nanobioprobe for signal amplification

(2020) Omotayo K. Adeniyi et al.   BIOSENSORS & BIOELECTRONICS

Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket

(2019) Mohan R Pradhan et al.   NUCLEIC ACIDS RESEARCH

The multiple mechanisms that regulate p53 activity and cell fate

(2019) Antonina Hafner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Multiplexed profiling of RNA and protein expression signatures in individual cells using flow or mass cytometry

(2019) Andrew D. Duckworth et al.   Nature Protocols

Mechanical insights into the regulation of programmed cell death by p53 via mitochondria

(2019) Kohji Yamada et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations

(2019) Ana Sara Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Target-Induced Cascade Amplification for Homogeneous Virus Detection

(2019) Mingyuan Du et al.   ANALYTICAL CHEMISTRY

Localized Visualization and Autonomous Detection of Cell Surface Receptor Clusters Using DNA Proximity Circuit

(2018) Yan Shan Ang et al.   ANALYTICAL CHEMISTRY

In Situ Monitoring of p53 Protein and MDM2 Protein Interaction in Single Living Cells Using Single-Molecule Fluorescence Spectroscopy

(2018) Zhixue Du et al.   ANALYTICAL CHEMISTRY

Target-induced proximity ligation triggers recombinase polymerase amplification and transcription-mediated amplification to detect tumor-derived exosomes in nasopharyngeal carcinoma with high sensitivity

(2018) Wanli Liu et al.   BIOSENSORS & BIOELECTRONICS

A disposable immunosensor using ITO based electrode modified by a star-shaped polymer for analysis of tumor suppressor protein p53 in human serum

(2018) Muhammet Aydın et al.   BIOSENSORS & BIOELECTRONICS

Rapid colorimetric detection of p53 protein function using DNA-gold nanoconjugates with applications for drug discovery and cancer diagnostics

(2018) Enock Assah et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Intrinsically disordered domain of tumor suppressor p53 facilitates target search by ultrafast transfer between different DNA strands

(2018) Yuji Itoh et al.   NUCLEIC ACIDS RESEARCH

Highly sensitive fluorescent detection of p53 protein based on DNA functionalized Fe 3 O 4 nanoparticles

(2018) Qunfang Xu et al.   TALANTA

Fiber Light-Coupled Optofluidic Waveguide (FLOW) Immunosensor for Highly Sensitive Detection of p53 Protein

(2018) Lili Liang et al.   ANALYTICAL CHEMISTRY

Restoring Guardianship of the Genome: Anticancer Drug Strategies to Reverse Oncogenic Mutant p53 Misfolding

(2018) Husam A. Babikir et al.   CANCER TREATMENT REVIEWS

Protein-responsive rolling circle amplification as a tandem template to drive amplified transduction of fluorescence signal probes for highly sensitive immunoassay

(2018) Wenting Yang et al.   CHEMICAL COMMUNICATIONS

Polymer-Ligand-Based ELISA for Robust, High-Throughput, Quantitative Detection of p53 Aggregates

(2018) Elisabeth Maritschnegg et al.   ANALYTICAL CHEMISTRY

The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1

(2017) Arthur Fischbach et al.   NUCLEIC ACIDS RESEARCH

An activity-dependent proximity ligation platform for spatially resolved quantification of active enzymes in single cells

(2017) Gang Li et al.   Nature Communications

Rapid agarose gel electrophoretic mobility shift assay for quantitating protein: RNA interactions

(2016) Jennifer A. Ream et al.   ANALYTICAL BIOCHEMISTRY

Detection of p53 Protein Based on Mesoporous Pt–Pd Nanoparticles with Enhanced Peroxidase-like Catalysis

(2016) Tao Jiang et al.   ACS Sensors

Dual-Targeting Nanovesicles for In Situ Intracellular Imaging of and Discrimination between Wild-type and Mutant p53

(2015) Ruocan Qian et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine

(2014) M. Monsur Ali et al.   CHEMICAL SOCIETY REVIEWS

Binding-Induced Formation of DNA Three-Way Junctions and Its Application to Protein Detection and DNA Strand Displacement

(2013) Feng Li et al.   ANALYTICAL CHEMISTRY

Assembling DNA through Affinity Binding to Achieve Ultrasensitive Protein Detection

(2013) Hongquan Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Doxorubicin induces cell death in breast cancer cells regardless of Survivin and XIAP expression levels

(2013) Gabriela Nestal de Moraes et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

(2010) Perry Stambolsky et al.   CANCER CELL

Nano-ELISA for highly sensitive protein detection

(2009) Chun-Ping Jia et al.   BIOSENSORS & BIOELECTRONICS

Capture of p53 by Electrodes Modified with Consensus DNA Duplexes and Amplified Voltammetric Detection Using Ferrocene-Capped Gold Nanoparticle/Streptavidin Conjugates

(2008) Jianxiu Wang et al.   ANALYTICAL CHEMISTRY