Ice Templating Soft Matter: Fundamental Principles and Fabrication Approaches to Tailor Pore Structure and Morphology and Their Biomedical Applications

Improvement of Bone Formation in Rats with Calvarial Defects by Modulating the Pore Size of Tricalcium Phosphate Scaffolds

(2020) Mineon Park et al.   BIOTECHNOLOGY AND BIOPROCESS ENGINEERING

Cellular Geometry Sensing at Different Length Scales and its Implications for Scaffold Design

(2020) Maike Werner et al.   Materials

Microchannels Are an Architectural Cue That Promotes Integration and Vascularization of Silk Biomaterials in Vivo

(2020) Fengying Tang et al.   ACS Biomaterials-Science & Engineering

Freeze Casting: From Low‐Dimensional Building Blocks to Aligned Porous Structures—A Review of Novel Materials, Methods, and Applications

(2020) Gaofeng Shao et al.   ADVANCED MATERIALS

Intrinsic and extrinsic control of freeze casting

(2019) Isaac Nelson et al.   Journal of Materials Research and Technology-JMR&T

Hydrogels and Their Applications in Targeted Drug Delivery

(2019) Radhika Narayanaswamy et al.   MOLECULES

Effects of post-processing methods on chitosan-genipin hydrogel properties

(2019) Abitha M. Heimbuck et al.   Materials Science & Engineering C-Materials for Biological Applications

Microchannels in Development, Survival, and Vascularisation of Tissue Analogues for Regenerative Medicine

(2019) Khoon S. Lim et al.   TRENDS IN BIOTECHNOLOGY

Plant-Derived Nanocellulose as Structural and Mechanical Reinforcement of Freeze-Cast Chitosan Scaffolds for Biomedical Applications

(2019) Kaiyang Yin et al.   BIOMACROMOLECULES

The Basics of Integra Dermal Regeneration Template and its Expanding Clinical Applications

(2019) Daniel K. Chang et al.   Seminars in Plastic Surgery

Cryoprotectant enables structural control of porous scaffolds for exploration of cellular mechano-responsiveness in 3D

(2019) Shumeng Jiang et al.   Nature Communications

Tissue Mimicry in Morphology and Composition Promotes Hierarchical Matrix Remodeling of Invading Stem Cells in Osteochondral and Meniscus Scaffolds

(2018) Kai Stuckensen et al.   ADVANCED MATERIALS

Cryostructuring of polymeric systems. 48. Influence of organic chaotropes and kosmotropes on the cryotropic gel-formation of aqueous poly(vinyl alcohol) solutions

(2018) Olga Yu Kolosova et al.   EUROPEAN POLYMER JOURNAL

Freeze casting – A review of processing, microstructure and properties via the open data repository, FreezeCasting.net

(2018) Kristen L. Scotti et al.   PROGRESS IN MATERIALS SCIENCE

The lure of ice-templating: Recent trends and opportunities for porous materials

(2018) Sylvain Deville   SCRIPTA MATERIALIA

Visualizing 3D Food Microstructure Using Tomographic Methods: Advantages and Disadvantages

(2018) Zi Wang et al.   Annual Review of Food Science and Technology

High-strength and self-recoverable silk fibroin cryogels with anisotropic swelling and mechanical properties

(2018) Berkant Yetiskin et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Anisotropic Freeze-Cast Collagen Scaffolds for Tissue Regeneration: How Processing Conditions Affect Structure and Properties in the Dry and Fully Hydrated States

(2018) Prajan Divakar et al.   Journal of the Mechanical Behavior of Biomedical Materials

Simultaneous structuring and mineralization of silk fibroin scaffolds

(2018) Michaela Rödel et al.   Journal of Tissue Engineering

Freeze-casting porous chitosan ureteral stents for improved drainage

(2018) Kaiyang Yin et al.   Acta Biomaterialia

Silk scaffolds with gradient pore structure and improved cell infiltration performance

(2018) Li Huang et al.   Materials Science & Engineering C-Materials for Biological Applications

Effect of crosslinking functionality on microstructure, mechanical properties, and in vitro cytocompatibility of cellulose nanocrystals reinforced poly (vinyl alcohol)/sodium alginate hybrid scaffolds

(2017) Anuj Kumar et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Perlecan and vascular endothelial growth factor-encoding DNA-loaded chitosan scaffolds promote angiogenesis and wound healing

(2017) Megan S. Lord et al.   JOURNAL OF CONTROLLED RELEASE

PLLA scaffolds produced by thermally induced phase separation (TIPS) allow human chondrocyte growth and extracellular matrix formation dependent on pore size

(2017) Gioacchino Conoscenti et al.   Materials Science & Engineering C-Materials for Biological Applications

Ice-templating of anisotropic structures with high permeability

(2017) Kendell M. Pawelec et al.   Materials Science & Engineering C-Materials for Biological Applications

Super-macroporous dextran cryogels via UV-induced crosslinking: synthesis and characterization

(2017) Georgy L Georgiev et al.   POLYMER INTERNATIONAL

Silk-based multilayered angle-ply annulus fibrosus construct to recapitulate form and function of the intervertebral disc

(2017) Bibhas K. Bhunia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modular assembly of thick multifunctional cardiac patches

(2017) Sharon Fleischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influence of Stage Cooling Method on Pore Architecture of Biomimetic Alginate Scaffolds

(2017) Yuanming Zhang et al.   Scientific Reports

Cartilage-like electrostatic stiffening of responsive cryogel scaffolds

(2017) G. S. Offeddu et al.   Scientific Reports

Composite Hydrogels with Tunable Anisotropic Morphologies and Mechanical Properties

(2016) Mokit Chau et al.   CHEMISTRY OF MATERIALS

Colloidal assembly by ice templating

(2016) Guruswamy Kumaraswamy et al.   FARADAY DISCUSSIONS

Phase field simulations of ice crystal growth in sugar solutions

(2016) R.G.M. van der Sman   INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER

Fabrication and characterization of aligned macroporous monolith for high-performance protein chromatography

(2016) Kaifeng Du et al.   JOURNAL OF CHROMATOGRAPHY A

Anisotropic silk fibroin/gelatin scaffolds from unidirectional freezing

(2016) Maria Christine Tankeh Asuncion et al.   Materials Science & Engineering C-Materials for Biological Applications

Vascularization and Angiogenesis in Tissue Engineering: Beyond Creating Static Networks

(2016) Jeroen Rouwkema et al.   TRENDS IN BIOTECHNOLOGY

Colloidal assembly by ice templating

(2016) Guruswamy Kumaraswamy et al.   FARADAY DISCUSSIONS

Sonication induced silk fibroin cryogels for tissue engineering applications

(2016) P U Kadakia et al.   Materials Research Express

Bioinspired Hydroxyapatite/Poly(methyl methacrylate) Composite with a Nacre-Mimetic Architecture by a Bidirectional Freezing Method

(2015) Hao Bai et al.   ADVANCED MATERIALS

DiameterJ: A validated open source nanofiber diameter measurement tool

(2015) Nathan A. Hotaling et al.   BIOMATERIALS

Biodegradation, biocompatibility, and osteoconduction evaluation of collagen-nanohydroxyapatite cryogels for bone tissue regeneration

(2015) Christiane Laranjo Salgado et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Altering crystal growth and annealing in ice-templated scaffolds

(2015) K. M. Pawelec et al.   JOURNAL OF MATERIALS SCIENCE

Investigation of structural collapse in unidirectionally freeze cast collagen scaffolds

(2015) Drew Clearfield et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Classification, processing and application of hydrogels: A review

(2015) Faheem Ullah et al.   Materials Science & Engineering C-Materials for Biological Applications

Collective cell migration: guidance principles and hierarchies

(2015) Anna Haeger et al.   TRENDS IN CELL BIOLOGY

Prospective and randomised evaluation of the protease-modulating effect of oxidised regenerated cellulose/collagen matrix treatment in pressure sore ulcers

(2015) Oliver Kloeters et al.   International Wound Journal

Lyophilized Silk Sponges: A Versatile Biomaterial Platform for Soft Tissue Engineering

(2015) Jelena Rnjak-Kovacina et al.   ACS Biomaterials-Science & Engineering

Lyophilized Silk Sponges: A Versatile Biomaterial Platform for Soft Tissue Engineering

(2015) Jelena Rnjak-Kovacina et al.   ACS Biomaterials Science & Engineering

Bioinspired large-scale aligned porous materials assembled with dual temperature gradients

(2015) H. Bai et al.   Science Advances

Ice-templated Self-assembly of VOPO4–Graphene Nanocomposites for Vertically Porous 3D Supercapacitor Electrodes

(2015) Kwang Hoon Lee et al.   Scientific Reports

Highly Tunable Elastomeric Silk Biomaterials

(2014) Benjamin P. Partlow et al.   ADVANCED FUNCTIONAL MATERIALS

Quantitative regulation of bone-mimetic, oriented collagen/apatite matrix structure depends on the degree of osteoblast alignment on oriented collagen substrates

(2014) Aira Matsugaki et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effects of processing parameters in thermally induced phase separation technique on porous architecture of scaffolds for bone tissue engineering

(2014) Rosa Akbarzadeh et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

A comparative study of oxygen diffusion in tissue engineering scaffolds

(2014) T. Fiedler et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Effect of porosity on mass transfer of gas absorption in a hollow fiber membrane contactor

(2014) Weidong Zhang et al.   JOURNAL OF MEMBRANE SCIENCE

Understanding anisotropy and architecture in ice-templated biopolymer scaffolds

(2014) K.M. Pawelec et al.   Materials Science & Engineering C-Materials for Biological Applications

On the development of ice-templated silicon carbide scaffolds for nature-inspired structural materials

(2013) Valentina Naglieri et al.   ACTA MATERIALIA

Porous Implants Modulate Healing and Induce Shifts in Local Macrophage Polarization in the Foreign Body Reaction

(2013) Eric M. Sussman et al.   ANNALS OF BIOMEDICAL ENGINEERING

The Pivotal Role of Vascularization in Tissue Engineering

(2013) François A. Auger et al.   Annual Review of Biomedical Engineering

Bio-inspired fabrication of fibroin cryogels from the muga silkworm Antheraea assamensis for liver tissue engineering

(2013) Banani Kundu et al.   Biomedical Materials

Engineering cell alignment in vitro

(2013) Yuhui Li et al.   BIOTECHNOLOGY ADVANCES

Prospective study on burns treated with Integra®, a cellulose sponge and split thickness skin graft

(2013) Heli Lagus et al.   BURNS

The effect of collagen–chitosan porous scaffold thickness on dermal regeneration in a one-stage grafting procedure

(2013) Shi Haifei et al.   Journal of the Mechanical Behavior of Biomedical Materials

Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size

(2013) Qiu Li Loh et al.   TISSUE ENGINEERING PART B-REVIEWS

Randomized controlled trial on collagen/oxidized regenerated cellulose/silver treatment

(2013) Finn Gottrup et al.   WOUND REPAIR AND REGENERATION

Cryogels for biomedical applications

(2013) Timothy M. A. Henderson et al.   Journal of Materials Chemistry B

Novel crosslinking methods to design hydrogels

(2012) W.E. Hennink et al.   ADVANCED DRUG DELIVERY REVIEWS

Engineering biomaterials to integrate and heal: The biocompatibility paradigm shifts

(2012) James D. Bryers et al.   BIOTECHNOLOGY AND BIOENGINEERING

Microstructure formation of maltodextrin and sugar matrices in freeze-dried systems

(2012) Nathdanai Harnkarnsujarit et al.   CARBOHYDRATE POLYMERS

Laminar Silk Scaffolds for Aligned Tissue Fabrication

(2012) Biman B. Mandal et al.   MACROMOLECULAR BIOSCIENCE

Injectable preformed scaffolds with shape-memory properties

(2012) S. A. Bencherif et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biomedical Applications of Chitosan: An Overview

(2012) R. Ramya et al.   Journal of Biomaterials and Tissue Engineering

Ice-template-induced silk fibroin–chitosan scaffolds with predefined microfluidic channels and fully porous structures

(2011) Mao Mao et al.   Acta Biomaterialia

Aligned silk-based 3-D architectures for contact guidance in tissue engineering

(2011) A.L. Oliveira et al.   Acta Biomaterialia

Biomimetic collagen scaffolds with anisotropic pore architecture

(2011) N. Davidenko et al.   Acta Biomaterialia

Investigation of structure formation during freeze-casting from very slow to very fast solidification velocities

(2011) T. Waschkies et al.   ACTA MATERIALIA

The effect of pore size on tissue ingrowth and neovascularization in porous bioceramics of controlled architecturein vivo

(2011) Bai Feng et al.   Biomedical Materials

Flash Freezing of Mohs Micrographic Surgery Tissue Can Minimize Freeze Artifact and Speed Slide Preparation

(2011) Quenby L. Erickson et al.   DERMATOLOGIC SURGERY

Freeze casting of porous materials: review of critical factors in microstructure evolution

(2011) W L Li et al.   INTERNATIONAL MATERIALS REVIEWS

Ice-Templating of Alumina Suspensions: Effect of Supercooling and Crystal Growth During the Initial Freezing Regime

(2011) Audrey Lasalle et al.   JOURNAL OF THE AMERICAN CERAMIC SOCIETY

Characterization and scanning electron microscopic investigation of crosslinked freeze dried gelatin matrices for study of drug diffusivity and release kinetics

(2011) Goutam Thakur et al.   MICRON

Macroporous, responsive DNA cryogel beads

(2011) Nermin Orakdogen et al.   REACTIVE & FUNCTIONAL POLYMERS

RepRap – the replicating rapid prototyper

(2011) Rhys Jones et al.   ROBOTICA

Topography, Cell Response, and Nerve Regeneration

(2010) Diane Hoffman-Kim et al.   Annual Review of Biomedical Engineering

The use of AlloDerm on major burn patients: AlloDerm prevents post-burn joint contracture

(2010) Haejun Yim et al.   BURNS

Green synthesis of chitosan-based nanofibers and their applications

(2010) Lei Qian et al.   GREEN CHEMISTRY

Construction and in vitro characterization of an optimized porosity-enabled amalgamated matrix for sustained transbuccal drug delivery

(2010) Oluwatoyin A. Adeleke et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Influence of Particle Size on Ice Nucleation and Growth During the Ice-Templating Process

(2010) Sylvain Deville et al.   JOURNAL OF THE AMERICAN CERAMIC SOCIETY

Biomaterials by freeze casting

(2010) U. G. K. Wegst et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Slow-Release Human Recombinant Bone Morphogenetic Protein-2 Embedded Within Electrospun Scaffolds for Regeneration of Bone Defect: In Vitro and In Vivo Evaluation

(2010) Samer Srouji et al.   TISSUE ENGINEERING PART A

Understanding the effect of mean pore size on cell activity in collagen-glycosaminoglycan scaffolds

(2010) Ciara M. Murphy et al.   Cell Adhesion & Migration

Three-dimensional visualization of in vitro cultivated chondrocytes inside porous gelatine scaffolds: A tomographic approach

(2009) R. Zehbe et al.   Acta Biomaterialia

Microporous collagen spheres produced via thermally induced phase separation for tissue regeneration

(2009) Hussila Keshaw et al.   Acta Biomaterialia

Engineering Substrate Topography at the Micro- and Nanoscale to Control Cell Function

(2009) Christopher J. Bettinger et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phase separation, pore structure, and properties of nanofibrous gelatin scaffolds

(2009) Xiaohua Liu et al.   BIOMATERIALS

The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering

(2009) Ciara M. Murphy et al.   BIOMATERIALS

A novel route to polymeric sub-micron fibers and their use as templates for inorganic structures

(2009) Lei Qian et al.   CHEMICAL COMMUNICATIONS

Review of biomaterial thermal property measurements in the cryogenic regime and their use for prediction of equilibrium and non-equilibrium freezing applications in cryobiology

(2009) Jeunghwan Choi et al.   CRYOBIOLOGY

Preparation of a Dense/Porous BiLayered Ceramic by Applying an Electric Field During Freeze Casting

(2009) Yumin Zhang et al.   JOURNAL OF THE AMERICAN CERAMIC SOCIETY

The Effect of Polyvinyl Alcohol on the Microstructure and Permeability of Freeze-Cast Alumina

(2009) Christopher Peko et al.   JOURNAL OF THE AMERICAN CERAMIC SOCIETY

Ice-Templated Materials: Sophisticated Structures Exhibiting Enhanced Functionalities Obtained after Unidirectional Freezing and Ice-Segregation-Induced Self-Assembly†

(2008) María C. Gutiérrez et al.   CHEMISTRY OF MATERIALS

Accordion-like honeycombs for tissue engineering of cardiac anisotropy

(2008) George C. Engelmayr et al.   NATURE MATERIALS

The use of MatriDerm® in early excision and simultaneous autologous skin grafting in burns—A pilot study

(2007) H. Ryssel et al.   BURNS

Engineering functionally graded tissue engineering scaffolds

(2007) K LEONG et al.   Journal of the Mechanical Behavior of Biomedical Materials