Engineering Chameleon Prodrug Nanovesicles to Increase Antigen Presentation and Inhibit PD‐L1 Expression for Circumventing Immune Resistance of Cancer

From Design to Clinic: Engineered Nanobiomaterials for Immune Normalization Therapy of Cancer

(2021) Madiha Saeed et al.   ADVANCED MATERIALS

Engineering Stimuli‐Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy

(2020) Bo Hou et al.   ADVANCED MATERIALS

Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy

(2020) Jing Gao et al.   ACTA PHARMACOLOGICA SINICA

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

(2020) Keisuke Yamamoto et al.   NATURE

Development of a pH-responsive polymersome inducing endoplasmic reticulum stress and autophagy blockade

(2020) Funeng Xu et al.   Science Advances

Engineering Prodrug Nanomedicine for Cancer Immunotherapy

(2020) Bin Yang et al.   Advanced Science

Overcoming immune resistance by sequential prodrug nanovesicles for promoting chemoimmunotherapy of cancer

(2020) Fengqi Zhou et al.   Nano Today

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Nanoengineered Immune Niches for Reprogramming the Immunosuppressive Tumor Microenvironment and Enhancing Cancer Immunotherapy

(2019) Hathaichanok Phuengkham et al.   ADVANCED MATERIALS

Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade

(2019) Fangyuan Zhou et al.   ADVANCED MATERIALS

Near‐Infrared‐II Molecular Dyes for Cancer Imaging and Surgery

(2019) Shoujun Zhu et al.   ADVANCED MATERIALS

Engineering nanoparticles to locally activate T cells in the tumor microenvironment

(2019) Dangge Wang et al.   Science Immunology

Sheddable Prodrug Vesicles Combating Adaptive Immune Resistance for Improved Photodynamic Immunotherapy of Cancer

(2019) Ang Gao et al.   NANO LETTERS

An Efficient 1064 nm NIR-II Excitation Fluorescent Molecular Dye for Deep-Tissue High-Resolution Dynamic Bioimaging

(2018) Benhao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemotherapy induces enrichment of CD47+/CD73+/PDL1+immune evasive triple-negative breast cancer cells

(2018) Debangshu Samanta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors

(2018) Tingting Wang et al.   Nature Communications

A bright organic NIR-II nanofluorophore for three-dimensional imaging into biological tissues

(2018) Hao Wan et al.   Nature Communications

Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma

(2018) Michaël Cerezo et al.   NATURE MEDICINE

Cancer immunoediting and resistance to T cell-based immunotherapy

(2018) Jake S. O’Donnell et al.   Nature Reviews Clinical Oncology

Acidity-Triggered Ligand-Presenting Nanoparticles To Overcome Sequential Drug Delivery Barriers to Tumors

(2017) Tingting Wang et al.   NANO LETTERS

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

(2017) Simon J. Hogg et al.   Cell Reports

Interferon Receptor Signaling Pathways Regulating PD-L1 and PD-L2 Expression

(2017) Angel Garcia-Diaz et al.   Cell Reports

Blocking autophagy improves the anti-tumor activity of afatinib in lung adenocarcinoma with activating EGFR mutations in vitro and in vivo

(2017) Xiangxiang Hu et al.   Scientific Reports

Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity

(2016) R. D. Dorand et al.   SCIENCE

BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression

(2016) Hengrui Zhu et al.   Cell Reports

Autophagy and autophagy-related proteins in the immune system

(2015) Shusaku T Shibutani et al.   NATURE IMMUNOLOGY

A small-molecule dye for NIR-II imaging

(2015) Alexander L. Antaris et al.   NATURE MATERIALS

Using tumour phylogenetics to identify the roots of metastasis in humans

(2015) Kamila Naxerova et al.   Nature Reviews Clinical Oncology

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

(2013) J. Y. Guo et al.   GENES & DEVELOPMENT

Tumor metastasis: moving new biological insights into the clinic

(2013) Liling Wan et al.   NATURE MEDICINE

Autophagy modulation as a potential therapeutic target for diverse diseases

(2012) David C. Rubinsztein et al.   NATURE REVIEWS DRUG DISCOVERY