Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity

MYC regulates the antitumor immune response through CD47 and PD-L1

(2016) S. C. Casey et al.   SCIENCE

Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma

(2015) C. D. Pham et al.   CLINICAL CANCER RESEARCH

Discovery and development of Seliciclib. How systems biology approaches can lead to better drug performance

(2015) Hilal S. Khalil et al.   JOURNAL OF BIOTECHNOLOGY

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer

(2015) Christina Twyman-Saint Victor et al.   NATURE

Control of pathogenic effector T-cell activities in situ by PD-L1 expression on respiratory inflammatory dendritic cells during respiratory syncytial virus infection

(2014) S Yao et al.   Mucosal Immunology

PD-L1 Expression Is Increased in a Subset of Basal Type Breast Cancer Cells

(2014) Hatem Soliman et al.   PLoS One

CD4 T-cell Subsets and Tumor Immunity: The Helpful and the Not-so-Helpful

(2014) H.-J. Kim et al.   Cancer Immunology Research

Extraneuronal activities and regulatory mechanisms of the atypical cyclin-dependent kinase Cdk5

(2012) Abul Arif   BIOCHEMICAL PHARMACOLOGY

Going out of the brain: Non-nervous system physiological and pathological functions of Cdk5

(2011) Erick Contreras-Vallejos et al.   CELLULAR SIGNALLING

Regulation of Androgen Receptor and Prostate Cancer Growth by Cyclin-dependent Kinase 5

(2011) Fu-Ning Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crosstalk between Medulloblastoma Cells and Endothelium Triggers a Strong Chemotactic Signal Recruiting T Lymphocytes to the Tumor Microenvironment

(2011) Vita S. Salsman et al.   PLoS One

Identification of a Phosphorylation-Dependent Nuclear Localization Motif in Interferon Regulatory Factor 2 Binding Protein 2

(2011) Allen C. T. Teng et al.   PLoS One

Inhibiting the Cyclin-Dependent Kinase CDK5 Blocks Pancreatic Cancer Formation and Progression through the Suppression of Ras-Ral Signaling

(2010) Georg Feldmann et al.   CANCER RESEARCH

IRF2BP2 is a skeletal and cardiac muscle-enriched ischemia-inducible activator of VEGFA expression

(2010) Allen C. T. Teng et al.   FASEB JOURNAL

Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis

(2010) Tej K. Pareek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cdk5-mediated Phosphorylation of c-Myc on Ser-62 Is Essential in Transcriptional Activation of Cyclin B1 by Cyclin G1

(2008) Haeng Ran Seo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdk5-mediated regulation of the PIKE-A-Akt pathway and glioblastoma cell invasion

(2008) R. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA