Sequentially pH-Responsive Drug-Delivery Nanosystem for Tumor Immunogenic Cell Death and Cooperating with Immune Checkpoint Blockade for Efficient Cancer Chemoimmunotherapy

A combinational chemo-immune therapy using an enzyme-sensitive nanoplatform for dual-drug delivery to specific sites by cascade targeting

(2021) Yanmei He et al.   Science Advances

Fullerenols boosting the therapeutic effect of anti-CD47 antibody to trigger robust anti-tumor immunity by inducing calreticulin exposure

(2021) Kui Chen et al.   Nano Today

Reversing Chemotherapy Resistance by a Synergy between Lysosomal pH-Activated Mitochondrial Drug Delivery and Erlotinib-Mediated Drug Efflux Inhibition

(2021) Furong Cheng et al.   ACS Applied Materials & Interfaces

Nanoenabled Disruption of Multiple Barriers in Antigen Cross-Presentation of Dendritic Cells via Calcium Interference for Enhanced Chemo-Immunotherapy

(2020) Jingyi An et al.   ACS Nano

Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy

(2020) Jing Gao et al.   ACTA PHARMACOLOGICA SINICA

Biomaterial-based strategies to prime dendritic cell-mediated anti-cancer immune responses

(2020) Wooram Park et al.   INTERNATIONAL MATERIALS REVIEWS

Synthetic Immunogenic Cell Death Mediated by Intracellular Delivery of STING Agonist Nanoshells Enhances Anticancer Chemo-immunotherapy

(2020) Saborni Chattopadhyay et al.   NANO LETTERS

Current Approaches for Combination Therapy of Cancer: The Role of Immunogenic Cell Death

(2020) Zahra Asadzadeh et al.   Cancers

Dendritic Cells and Immunogenic Cancer Cell Death: A Combination for Improving Antitumor Immunity

(2020) María Julia Lamberti et al.   Pharmaceutics

Nanoparticle-enhanced chemo-immunotherapy to trigger robust antitumor immunity

(2020) Jingjing Liang et al.   Science Advances

Targeting immunogenic cell death in cancer

(2020) Asma Ahmed et al.   Molecular Oncology

High-Density Lipoprotein-Mimicking Nanodiscs for Chemo-immunotherapy against Glioblastoma Multiforme

(2019) Padma Kadiyala et al.   ACS Nano

Immunogenic cell death in cancer therapy: Present and emerging inducers

(2019) Jingyi Zhou et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

cGAS/STING axis mediates a topoisomerase II inhibitor–induced tumor immunogenicity

(2019) Zining Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Bioinspired Hybrid Protein Oxygen Nanocarrier Amplified Photodynamic Therapy for Eliciting Anti-tumor Immunity and Abscopal Effect

(2018) Zhikuan Chen et al.   ACS Nano

Autophagy and doxorubicin resistance in cancer

(2018) Chao Chen et al.   ANTI-CANCER DRUGS

Highly enhanced cancer immunotherapy by combining nanovaccine with hyaluronidase

(2018) Xiuwen Guan et al.   BIOMATERIALS

CD8+ T-cell exhaustion in cancer: mechanisms and new area for cancer immunotherapy

(2018) Qi-Feng He et al.   Briefings in Functional Genomics

Immunogenic Apoptosis as a Novel Tool for Anticancer Vaccine Development

(2018) Barbara Montico et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immunochemotherapy mediated by thermosponge nanoparticles for synergistic anti-tumor effects

(2018) Yongdan Zhao et al.   JOURNAL OF CONTROLLED RELEASE

The inducers of immunogenic cell death for tumor immunotherapy

(2018) Xiuying Li   TUMORI

The inducers of immunogenic cell death for tumor immunotherapy

(2018) Xiuying Li   TUMORI JOURNAL

Immunogenic cell death in anticancer chemotherapy and its impact on clinical studies

(2018) Qiang Wang et al.   CANCER LETTERS

Facile synthesis of pH-responsive doxorubicin-loaded layered double hydroxide for efficient cancer therapy

(2018) Abdul Hakeem et al.   Journal of Materials Chemistry B

Dendritic Cells and CD8 T Cell Immunity in Tumor Microenvironment

(2018) Chunmei Fu et al.   Frontiers in Immunology

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

A Powerful CD8+T-Cell Stimulating D-Tetra-Peptide Hydrogel as a Very Promising Vaccine Adjuvant

(2016) Zichao Luo et al.   ADVANCED MATERIALS

Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy

(2016) Xiao Zhao et al.   BIOMATERIALS

Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy

(2016) Christina Pfirschke et al.   IMMUNITY

Ultrasensitive pH Triggered Charge/Size Dual-Rebound Gene Delivery System

(2016) Xiuwen Guan et al.   NANO LETTERS

Erythrocyte Membrane-Enveloped Polymeric Nanoparticles as Nanovaccine for Induction of Antitumor Immunity against Melanoma

(2015) Yuanyuan Guo et al.   ACS Nano

Concepts and mechanisms underlying chemotherapy induced immunogenic cell death: impact on clinical studies and considerations for combined therapies

(2015) Simon Gebremeskel et al.   Oncotarget

Combinatorial Strategies for the Induction of Immunogenic Cell Death

(2015) Lucillia Bezu et al.   Frontiers in Immunology

A pH-sensitive charge-conversion system for doxorubicin delivery

(2013) Xiuwen Guan et al.   Acta Biomaterialia

Innate and adaptive immune cells in the tumor microenvironment

(2013) Thomas F Gajewski et al.   NATURE IMMUNOLOGY

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

(2011) M. Michaud et al.   SCIENCE

The immunogenicity of tumor cell death

(2008) Oliver Kepp et al.   CURRENT OPINION IN ONCOLOGY