Fullerenols boosting the therapeutic effect of anti-CD47 antibody to trigger robust anti-tumor immunity by inducing calreticulin exposure

Fractionated regimen-suitable immunoradiotherapy sensitizer based on ultrasmall Fe4Se2W18 nanoclusters enable tumor-specific radiosensitization augment and antitumor immunity boost

(2020) Ruyi Zhou et al.   Nano Today

Nanoparticle enhanced MRI can monitor macrophage response to CD47 mAb immunotherapy in osteosarcoma

(2019) Suchismita Mohanty et al.   Cell Death & Disease

Rab7a modulates ER stress and ER morphology

(2018) Duarte Mateus et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

eIF2α phosphorylation is pathognomonic for immunogenic cell death

(2018) Lucillia Bezu et al.   CELL DEATH AND DIFFERENTIATION

Immunotherapy for osteosarcoma: Where do we go from here?

(2018) Mary F. Wedekind et al.   PEDIATRIC BLOOD & CANCER

Small size fullerenol nanoparticles suppress lung metastasis of breast cancer cell by disrupting actin dynamics

(2018) Yanxia Qin et al.   JOURNAL OF NANOBIOTECHNOLOGY

A designer self-assembled supramolecule amplifies macrophage immune responses against aggressive cancer

(2018) Ashish Kulkarni et al.   Nature Biomedical Engineering

Trial watch: peptide-based vaccines in anticancer therapy

(2018) Lucillia Bezu et al.   OncoImmunology

Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models

(2018) Ioanna Keklikoglou et al.   NATURE CELL BIOLOGY

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

(2017) Sharareh Gholamin et al.   Science Translational Medicine

Rainbow peacock spiders inspire miniature super-iridescent optics

(2017) Bor-Kai Hsiung et al.   Nature Communications

Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

(2016) J. Fucikova et al.   BLOOD

Calreticulin Expression in Human Non–Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable Prognosis

(2016) Jitka Fucikova et al.   CANCER RESEARCH

Fullerenol Nanoparticles with Structural Activity Induce Variable Intracellular Actin Filament Morphologies

(2016) Junjiang Jin et al.   Journal of Biomedical Nanotechnology

M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide

(2015) Marie Genin et al.   BMC CANCER

Endoplasmic Reticulum Stress Induced by Zinc Oxide Nanoparticles Is an Earlier Biomarker for Nanotoxicological Evaluation

(2014) Rui Chen et al.   ACS Nano

Rab18 and a Rab18 GEF complex are required for normal ER structure

(2014) Andreas Gerondopoulos et al.   JOURNAL OF CELL BIOLOGY

Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response

(2013) D. Tseng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endoplasmic reticulum stress preconditioning attenuates methylmercury-induced cellular damage by inducing favorable stress responses

(2013) Fusako Usuki et al.   Scientific Reports

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

PEI-derivatized fullerene drug delivery using folate as a homing device targeting to tumor

(2012) Jinjin Shi et al.   BIOMATERIALS

The CD47–SIRPα pathway in cancer immune evasion and potential therapeutic implications

(2012) Mark P Chao et al.   CURRENT OPINION IN IMMUNOLOGY

Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells

(2012) Fengfeng Ping et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Calreticulin signaling in health and disease

(2012) Wen-An Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Rab10 GTPase regulates ER dynamics and morphology

(2012) Amber R. English et al.   NATURE CELL BIOLOGY

ER stress-induced inflammation: does it aid or impede disease progression?

(2012) Abhishek D. Garg et al.   TRENDS IN MOLECULAR MEDICINE

Separation and purification of fullerenols for improved biocompatibility

(2011) Juan Li et al.   CARBON

Endoplasmic Reticulum Calcium Depletion Impacts Chaperone Secretion, Innate Immunity, and Phagocytic Uptake of Cells

(2011) L. R. Peters et al.   JOURNAL OF IMMUNOLOGY

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

(2010) M. P. Chao et al.   Science Translational Medicine

Fullerenol−Cytotoxic Conjugates for Cancer Chemotherapy

(2009) Padmaparna Chaudhuri et al.   ACS Nano

CD47 Is an Adverse Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

(2009) Ravindra Majeti et al.   CELL

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death

(2009) Theocharis Panaretakis et al.   EMBO JOURNAL

Immunogenic anti-cancer chemotherapy as an emerging concept

(2008) Nicole M Haynes et al.   CURRENT OPINION IN IMMUNOLOGY