Transcription Factor Activity Inference in Systemic Lupus Erythematosus

Integrative Analysis Reveals a Molecular Stratification of Systemic Autoimmune Diseases

(2020) Guillermo Barturen et al.   Arthritis & Rheumatology

Lupus in crisis: as failures pile up, clinicians call for new tools

(2019) Elie Dolgin   NATURE BIOTECHNOLOGY

New Attempts to Define and Clarify Lupus

(2019) Marta E. Alarcón-Riquelme   Current Rheumatology Reports

Benchmark and integration of resources for the estimation of human transcription factor activities

(2019) Luz Garcia-Alonso et al.   GENOME RESEARCH

The neutrophil-lymphocyte ratio in early rheumatoid arthritis and its ability to predict subsequent failure of triple therapy

(2019) Daniel Boulos et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

The Neutrophil-to-Lymphocyte Ratio is Related to Disease Activity in Relapsing Remitting Multiple Sclerosis

(2019) D’Amico et al.   Cells

HLA-C1 ligands are associated with increased susceptibility to systemic lupus erythematosus

(2018) Caterina Maria Gambino et al.   HUMAN IMMUNOLOGY

Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity

(2018) John B. Harley et al.   NATURE GENETICS

GATA4 regulates angiogenesis and persistence of inflammation in rheumatoid arthritis

(2018) Wanwan Jia et al.   Cell Death & Disease

Multi-omics monitoring of drug response in rheumatoid arthritis in pursuit of molecular remission

(2018) Shinya Tasaki et al.   Nature Communications

A critical role of E2F transcription factor 2 in proinflammatory cytokines-dependent proliferation and invasiveness of fibroblast-like synoviocytes in rheumatoid Arthritis

(2018) Rui Zhang et al.   Scientific Reports

Longitudinal Stratification of Gene Expression Reveals Three SLE Groups of Disease Activity Progression

(2018) Daniel Toro-Domínguez et al.   Arthritis & Rheumatology

Retinoic Acid, Leaky Gut, and Autoimmune Diseases

(2018) Leila Abdelhamid et al.   Nutrients

Meta-analysis of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio in rheumatoid arthritis

(2018) Gian Luca Erre et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Circadian clock cryptochrome proteins regulate autoimmunity

(2017) Qi Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective

(2017) Vaishali R. Moulton et al.   TRENDS IN MOLECULAR MEDICINE

Environmental sensing by mature B cells is controlled by the transcription factors PU.1 and SpiB

(2017) Simon N. Willis et al.   Nature Communications

Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients

(2016) Romain Banchereau et al.   CELL

The Role of STAT Signaling Pathways in the Pathogenesis of Systemic Lupus Erythematosus

(2016) Aleš Goropevšek et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Vitamin A improve Th17 and Treg regulation in systemic lupus erythematosus

(2016) Kusworini Handono et al.   CLINICAL RHEUMATOLOGY

Rel B-modified dendritic cells possess tolerogenic phenotype and functions on lupus splenic lymphocytesin vitro

(2016) Haijing Wu et al.   IMMUNOLOGY

The genetic basis of systemic lupus erythematosus: What are the risk factors and what have we learned

(2016) Maria Teruel et al.   JOURNAL OF AUTOIMMUNITY

Systemic lupus erythematosus diagnosis and management

(2016) Bernard Thong et al.   RHEUMATOLOGY

Clinical Application of a Modular Genomics Technique in Systemic Lupus Erythematosus: Progress towards Precision Medicine

(2016) Eric Zollars et al.   International Journal of Genomics

Pin1-Targeted Therapy for Systemic Lupus Erythematosus

(2016) Shuo Wei et al.   Arthritis & Rheumatology

Targeting Syk in Autoimmune Rheumatic Diseases

(2016) Guo-Min Deng et al.   Frontiers in Immunology

The pan-cancer pathological regulatory landscape

(2016) Matias M. Falco et al.   Scientific Reports

The role of neutrophils in the pathogenesis of systemic lupus erythematosus

(2015) Carolyne K. Smith et al.   CURRENT OPINION IN RHEUMATOLOGY

Robust enumeration of cell subsets from tissue expression profiles

(2015) Aaron M Newman et al.   NATURE METHODS

Tacrolimus Protects Podocytes from Injury in Lupus Nephritis Partly by Stabilizing the Cytoskeleton and Inhibiting Podocyte Apoptosis

(2015) Ruyi Liao et al.   PLoS One

Measuring disease activity in adults with systemic lupus erythematosus: the challenges of administrative burden and responsiveness to patient concerns in clinical research

(2015) Jamal Mikdashi et al.   ARTHRITIS RESEARCH & THERAPY

Interferon Regulatory Factor 1 Marks Activated Genes and Can Induce Target Gene Expression in Systemic Lupus Erythematosus

(2015) Zhe Zhang et al.   Arthritis & Rheumatology

Dynamics of Gut Microbiota in Autoimmune Lupus

(2014) Husen Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Epigenomic elements enriched in the promoters of autoimmunity susceptibility genes

(2013) Mikhail G Dozmorov et al.   Epigenetics

Modulation by Melatonin of the Pathogenesis of Inflammatory Autoimmune Diseases

(2013) Gu-Jiun Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

(2013) Amy M. Becker et al.   PLoS One

Spleen Tyrosine Kinase (Syk) Regulates Systemic Lupus Erythematosus (SLE) T Cell Signaling

(2013) Alexandros P. Grammatikos et al.   PLoS One

Regulation of nuclear factor-κB in autoimmunity

(2013) Shao-Cong Sun et al.   TRENDS IN IMMUNOLOGY

Evaluation of calcineurin/NFAT inhibitor selectivity in primary human Th cells using bar-coding and phospho-flow cytometry

(2012) Stefan Frischbutter et al.   CYTOMETRY PART A

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways

(2012) Vincent F-S Shih et al.   NATURE IMMUNOLOGY

Activated NF-κB in Bone Marrow Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients Inhibits Osteogenic Differentiation Through Downregulating Smad Signaling

(2012) Yu Tang et al.   STEM CELLS AND DEVELOPMENT

Calcium signaling in systemic lupus erythematosus T cells: A treatment target

(2011) Vasileios C. Kyttaris et al.   ARTHRITIS AND RHEUMATISM

Measures of adult systemic lupus erythematosus: Updated Version of British Isles Lupus Assessment Group (BILAG 2004), European Consensus Lupus Activity Measurements (ECLAM), Systemic Lupus Activity Measure, Revised (SLAM-R), Systemic Lupus Activity Questi

(2011) Juanita Romero-Diaz et al.   ARTHRITIS CARE & RESEARCH

Transcription factor regulation can be accurately predicted from the presence of target gene signatures in microarray gene expression data

(2010) Ahmed Essaghir et al.   NUCLEIC ACIDS RESEARCH

Regulation of major histocompatibility complex class II gene expression, genetic variation and disease

(2009) L Handunnetthi et al.   GENES AND IMMUNITY

PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

(2009) Lata Mukundan et al.   NATURE MEDICINE