New Attempts to Define and Clarify Lupus

Type I IFN–related NETosis in ataxia telangiectasia and Artemis deficiency

(2018) Ersin Gul et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity

(2018) John B. Harley et al.   NATURE GENETICS

Moving towards a molecular taxonomy of autoimmune rheumatic diseases

(2018) Guillermo Barturen et al.   Nature Reviews Rheumatology

Whole Exome Sequencing of Patients from Multicase Families with Systemic Lupus Erythematosus Identifies Multiple Rare Variants

(2018) Angélica M. Delgado-Vega et al.   Scientific Reports

Longitudinal Stratification of Gene Expression Reveals Three SLE Groups of Disease Activity Progression

(2018) Daniel Toro-Domínguez et al.   Arthritis & Rheumatology

Genome-Wide DNA Methylation Analysis of Chinese Patients with Systemic Lupus Erythematosus Identified Hypomethylation in Genes Related to the Type I Interferon Pathway

(2017) Kit San Yeung et al.   PLoS One

IFI44Lpromoter methylation as a blood biomarker for systemic lupus erythematosus

(2016) Ming Zhao et al.   ANNALS OF THE RHEUMATIC DISEASES

Familial chilblain lupus due to a gain-of-function mutation in STING

(2016) Nadja König et al.   ANNALS OF THE RHEUMATIC DISEASES

Epigenetic alterations underlying autoimmune diseases

(2016) Saeed Aslani et al.   AUTOIMMUNITY

Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients

(2016) Romain Banchereau et al.   CELL

Systemic Lupus Erythematosus and Deficiencies of Early Components of the Complement Classical Pathway

(2016) Ana Catarina Lunz Macedo et al.   Frontiers in Immunology

Type I interferonopathies: Mendelian type I interferon up-regulation

(2015) Yanick J Crow   CURRENT OPINION IN IMMUNOLOGY

T Cell Transcriptomes Describe Patient Subtypes in Systemic Lupus Erythematosus

(2015) Sean J. Bradley et al.   PLoS One

Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies

(2014) Nezam Altorok et al.   ANNALS OF THE RHEUMATIC DISEASES

Shared signatures between rheumatoid arthritis, systemic lupus erythematosus and Sjögren’s syndrome uncovered through gene expression meta-analysis

(2014) Daniel Toro-Domínguez et al.   ARTHRITIS RESEARCH & THERAPY

Genome-wide DNA methylation study suggests epigenetic accessibility and transcriptional poising of interferon-regulated genes in naïve CD4+ T cells from lupus patients

(2013) Patrick Coit et al.   JOURNAL OF AUTOIMMUNITY

Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations

(2013) Devin M. Absher et al.   PLoS Genetics

Genome-Wide DNA Methylation Patterns in Naive CD4+ T Cells From Patients With Primary Sjögren's Syndrome

(2013) Nezam Altorok et al.   Arthritis & Rheumatology

Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations

(2012) Elena Sánchez et al.   ARTHRITIS AND RHEUMATISM

Common and specific signatures of gene expression and protein–protein interactions in autoimmune diseases

(2012) T Tuller et al.   GENES AND IMMUNITY

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Patients with systemic lupus erythematosus, myositis, rheumatoid arthritis and scleroderma share activation of a common type I interferon pathway

(2011) B. W. Higgs et al.   ANNALS OF THE RHEUMATIC DISEASES

Intakes of Vitamin B6 and Dietary Fiber and Clinical Course of Systemic Lupus Erythematosus: A Prospective Study of Japanese Female Patients

(2011) Yuko Minami et al.   JOURNAL OF EPIDEMIOLOGY

Systemic sclerosis and lupus: Points in an interferon-mediated continuum

(2010) Shervin Assassi et al.   ARTHRITIS AND RHEUMATISM

C1q Deficiency Leads to the Defective Suppression of IFN-  in Response to Nucleoprotein Containing Immune Complexes

(2010) D. M. Santer et al.   JOURNAL OF IMMUNOLOGY

Nutritional developmental epigenomics: immediate and long-lasting effects

(2010) L. Attig et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Molecular Signals of Epigenetic States

(2010) Roberto Bonasio et al.   SCIENCE

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

(2009) B. M. Javierre et al.   GENOME RESEARCH

Abnormal DNA methylation in CD4+ T cells from patients with systemic lupus erythematosus, systemic sclerosis, and dermatomyositis

(2009) W Lei et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY