SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

Systematic Comparison of Gene Expression between Murine Memory and Naive B Cells Demonstrates That Memory B Cells Have Unique Signaling Capabilities

(2014) M. M. Tomayko et al.   JOURNAL OF IMMUNOLOGY

Genome, epigenome and transcriptome analyses of a pair of monozygotic twins discordant for systemic lupus erythematosus

(2012) Hiroshi Furukawa et al.   HUMAN IMMUNOLOGY

Role of type I interferons in the activation of autoreactive B cells

(2012) Kerstin Kiefer et al.   IMMUNOLOGY AND CELL BIOLOGY

Induction of type I IFNs by intracellular DNA-sensing pathways

(2012) Taner Cavlar et al.   IMMUNOLOGY AND CELL BIOLOGY

Dual regulation of IRF4 function in T and B cells is required for the coordination of T–B cell interactions and the prevention of autoimmunity

(2012) Partha S. Biswas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular Characterization of Circulating Plasma Cells in Patients with Active Systemic Lupus Erythematosus

(2012) Patricia L. Lugar et al.   PLoS One

The genetics of lupus: a functional perspective

(2012) Sandra G Guerra et al.   ARTHRITIS RESEARCH & THERAPY

IL-12 selectively programs effector pathways that are stably expressed in human CD8+ effector memory T cells in vivo

(2011) F. Z. Chowdhury et al.   BLOOD

Interferon-α induces unabated production of short-lived plasma cells in pre-autoimmune lupus-prone (NZB×NZW)F1 mice but not in BALB/c mice

(2011) Alexis Mathian et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mapping a Dynamic Innate Immunity Protein Interaction Network Regulating Type I Interferon Production

(2011) Shitao Li et al.   IMMUNITY

The PYHIN protein family as mediators of host defenses

(2011) Stefan A. Schattgen et al.   IMMUNOLOGICAL REVIEWS

IFN-  Confers Resistance of Systemic Lupus Erythematosus Nephritis to Therapy in NZB/W F1 Mice

(2011) Z. Liu et al.   JOURNAL OF IMMUNOLOGY

Autoimmune Disease Risk Variant of IFIH1 Is Associated with Increased Sensitivity to IFN-  and Serologic Autoimmunity in Lupus Patients

(2011) T. Robinson et al.   JOURNAL OF IMMUNOLOGY

Ifih1 Gene Dose Effect Reveals MDA5-Mediated Chronic Type I IFN Gene Signature, Viral Resistance, and Accelerated Autoimmunity

(2011) S. P. Crampton et al.   JOURNAL OF IMMUNOLOGY

Emerging Roles for the Interferon-Inducible p200-Family Proteins in Sex Bias in Systemic Lupus Erythematosus

(2011) Divaker Choubey et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Interferon-Alpha Triggers B Cell Effector 1 (Be1) Commitment

(2011) Marie-Ghislaine de Goër de Herve et al.   PLoS One

IRF8 Governs Expression of Genes Involved in Innate and Adaptive Immunity in Human and Mouse Germinal Center B Cells

(2011) Dong-Mi Shin et al.   PLoS One

The type I interferon system in the etiopathogenesis of autoimmune diseases

(2011) Lars Rönnblom   UPSALA JOURNAL OF MEDICAL SCIENCES

Ribosomal P autoantibodies are present before SLE onset and are directed against non-C-terminal peptides

(2010) Latisha D. Heinlen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

(2010) T. Satoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutralization of interferon-α/β-inducible genes and downstream effect in a phase I trial of an anti-interferon-α monoclonal antibody in systemic lupus erythematosus

(2009) Yihong Yao et al.   ARTHRITIS AND RHEUMATISM

Interferon signature gene expression is correlated with autoantibody profiles in patients with incomplete lupus syndromes

(2009) Q.-Z. Li et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Monocytes and T lymphocytes contribute to a predominance of interleukin 6 and interleukin 10 in systemic lupus erythematosus

(2009) Susana Mellor-Pita et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

The CDK domain of p21 is a suppressor of IL-1β-mediated inflammation in activated macrophages

(2009) John C. Scatizzi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A regulatory SNP at position −899 in CDKN1A is associated with systemic lupus erythematosus and lupus nephritis

(2009) K Kim et al.   GENES AND IMMUNITY

The regulation of inflammation by galectin-3

(2009) Neil C. Henderson et al.   IMMUNOLOGICAL REVIEWS

Identification and Characterization of a Human CD5+ Pre-Naive B Cell Population

(2009) J. Lee et al.   JOURNAL OF IMMUNOLOGY

Interleukin 21 as a target of intervention in autoimmune disease

(2008) R Ettinger et al.   ANNALS OF THE RHEUMATIC DISEASES

Sialic acid-binding Ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus

(2008) Robert Biesen et al.   ARTHRITIS AND RHEUMATISM

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: Delineation by expression of CD27, IgD, and CD95

(2008) Annett M. Jacobi et al.   ARTHRITIS AND RHEUMATISM

Altered B cell receptor signaling in human systemic lupus erythematosus

(2008) Scott A. Jenks et al.   AUTOIMMUNITY REVIEWS

The Metallothionein/Thionein System: An Oxidoreductive Metabolic Zinc Link

(2008) Stephen G. Bell et al.   CHEMBIOCHEM

A novel subset of memory B cells is enriched in autoreactivity and correlates with adverse outcomes in SLE

(2008) Matilda W. Nicholas et al.   CLINICAL IMMUNOLOGY

N-Glycans in cancer progression

(2008) K. S Lau et al.   GLYCOBIOLOGY

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity

(2008) Jared M. Odegard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ETV6 mutations and loss in AML-M0

(2008) F P G Silva et al.   LEUKEMIA

Collaboration, Genetic Associations, and Lupus Erythematosus

(2008) Mary K. Crow   NEW ENGLAND JOURNAL OF MEDICINE

Autoreactive IgG memory antibodies in patients with systemic lupus erythematosus arise from nonreactive and polyreactive precursors

(2008) B. Mietzner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA