Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

Local translation in neurons: visualization and function

(2019) Christine E. Holt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Microtubules as platforms for probing liquid–liquid phase separation in cells – application to RNA-binding proteins

(2018) Alexandre Maucuer et al.   JOURNAL OF CELL SCIENCE

A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation

(2018) Yan Zhang et al.   MOLECULAR CELL

Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28

(2018) Longfei Wang et al.   Cell Reports

Cold shock proteins: from cellular mechanisms to pathophysiology and disease

(2018) Jonathan A. Lindquist et al.   Cell Communication and Signaling

Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration

(2018) Xue-Wei Wang et al.   Cell Reports

YB-1, an abundant core mRNA-binding protein, has the capacity to form an RNA nucleoprotein filament: a structural analysis

(2018) Dmitry A Kretov et al.   NUCLEIC ACIDS RESEARCH

Lin28 is induced in primed embryonic stem cells and regulates let-7-independent events

(2017) Silvia Parisi et al.   FASEB JOURNAL

The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules

(2017) Anthony Khong et al.   MOLECULAR CELL

H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance

(2017) Fei Peng et al.   Cell Death & Disease

LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation

(2017) Longfei Wang et al.   Cell Reports

Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer

(2017) Jun Yin et al.   PLoS One

LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency

(2016) Jin Zhang et al.   Cell Stem Cell

Principles and Properties of Stress Granules

(2016) David S.W. Protter et al.   TRENDS IN CELL BIOLOGY

The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion

(2015) Guramrit Singh et al.   Annual Review of Biochemistry

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

(2015) Amal M. El-Naggar et al.   CANCER CELL

eIF3 targets cell-proliferation messenger RNAs for translational activation or repression

(2015) Amy S. Y. Lee et al.   NATURE

mRNA and DNA selection via protein multimerization: YB-1 as a case study

(2015) Dmitry A. Kretov et al.   NUCLEIC ACIDS RESEARCH

Probing protein interactions in living mammalian cells on a microtubule bench

(2015) Mirela Boca et al.   Scientific Reports

Regulation of mRNA translation during mitosis

(2015) Marvin E Tanenbaum et al.   eLife

Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules

(2014) Ouissame Bounedjah et al.   NUCLEIC ACIDS RESEARCH

Lin28a regulates neuronal differentiation and controls miR-9 production

(2014) Jakub S. Nowak et al.   Nature Communications

Lin28: Primal Regulator of Growth and Metabolism in Stem Cells

(2013) Ng Shyh-Chang et al.   Cell Stem Cell

Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells

(2013) Liying Yan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular basis of UG-rich RNA recognition by the human splicing factor TDP-43

(2013) Peter J Lukavsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

LIN28A Is a Suppressor of ER-Associated Translation in Embryonic Stem Cells

(2012) Jun Cho et al.   CELL

LIN28 Binds Messenger RNAs at GGAGA Motifs and Regulates Splicing Factor Abundance

(2012) Melissa L. Wilbert et al.   MOLECULAR CELL

The Lin28 cold-shock domain remodels pre-let-7 microRNA

(2012) Florian Mayr et al.   NUCLEIC ACIDS RESEARCH

Molecular Basis for Interaction of let-7 MicroRNAs with Lin28

(2011) Yunsun Nam et al.   CELL

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28

(2011) Fionna E Loughlin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-Wide Studies Reveal That Lin28 Enhances the Translation of Genes Important for Growth and Survival of Human Embryonic Stem Cells

(2011) Shuping Peng et al.   STEM CELLS

LIN28 alters cell fate succession and acts independently of the let-7 microRNA during neurogliogenesis in vitro

(2010) E. Balzer et al.   DEVELOPMENT

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer

(2010) S Peng et al.   ONCOGENE

The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse

(2009) Ke Zheng et al.   BMC DEVELOPMENTAL BIOLOGY

Lin28-let7 Modulates Radiosensitivity of Human Cancer Cells With Activation of K-Ras

(2009) Jee-Sun Oh et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

A role for Lin28 in primordial germ-cell development and germ-cell malignancy

(2009) Jason A. West et al.   NATURE

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

Colocalization of fluorescent markers in confocal microscope images of plant cells

(2008) Andrew P French et al.   Nature Protocols

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE

P-LINCS:  A Parallel Linear Constraint Solver for Molecular Simulation

(2007) Berk Hess   Journal of Chemical Theory and Computation