Cold shock proteins: from cellular mechanisms to pathophysiology and disease

Structural features of the interaction of the 3′-untranslated region of mRNA containing exosomal RNA-specific motifs with YB-1, a potential mediator of mRNA sorting

(2018) Darya D. Yanshina et al.   BIOCHIMIE

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

(2018) Sebastian Markmiller et al.   CELL

Correction to: Cellular mechanisms responsible for cell-to-cell spreading of prions

(2018) Didier Vilette et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

YBX1 at the crossroads of non-coding transcriptome, exosomal, and cytoplasmic granular signaling

(2018) Padmanaban S. Suresh et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Anti-proliferative and pro-apoptotic effects of Uncaria tomentosa aqueous extract in squamous carcinoma cells

(2018) Francesca Ciani et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chilled in Translation: Adapting to Bacterial Climate Change

(2018) Susan Gottesman   MOLECULAR CELL

High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies

(2018) Ji-Young Youn et al.   MOLECULAR CELL

A Stress Response that Monitors and Regulates mRNA Structure Is Central to Cold Shock Adaptation

(2018) Yan Zhang et al.   MOLECULAR CELL

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons

(2018) Yingxiao Shi et al.   NATURE MEDICINE

RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome

(2018) Briana Van Treeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA buffers the phase separation behavior of prion-like RNA binding proteins

(2018) Shovamayee Maharana et al.   SCIENCE

O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress

(2017) Weiqi Xu et al.   JOURNAL OF HEPATOLOGY

Regulation of endogenous brakes to kidney fibrosis: turning the view upside down

(2017) Jonathan A. Lindquist et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Inflammatory cell infiltration and resolution of kidney inflammation is orchestrated by the cold-shock protein Y-box binding protein-1

(2017) Anja Bernhardt et al.   KIDNEY INTERNATIONAL

Protein O-GlcNAcylation: emerging mechanisms and functions

(2017) Xiaoyong Yang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

20 years of the SMART protein domain annotation resource

(2017) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

UNR/CDSE1 expression as prognosis biomarker in resectable pancreatic ductal adenocarcinoma patients: A proof-of-concept

(2017) Javier Martinez-Useros et al.   PLoS One

Macrophage Phenotype in Liver Injury and Repair

(2017) Y.-Y. Sun et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

RNA binding proteins and the pathological cascade in ALS/FTD neurodegeneration

(2017) Daisuke Ito et al.   Science Translational Medicine

Pathways of Unconventional Protein Secretion

(2017) Catherine Rabouille   TRENDS IN CELL BIOLOGY

NEMO Links Nuclear Factor-κB to Human Diseases

(2017) Gunter Maubach et al.   TRENDS IN MOLECULAR MEDICINE

A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells

(2017) Hyun Ju Lee et al.   Nature Communications

Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders

(2017) Brandon Maziuk et al.   Frontiers in Molecular Neuroscience

Antisense Oligonucleotides Targeting Y-Box Binding Protein-1 Inhibit Tumor Angiogenesis by Downregulating Bcl-xL-VEGFR2/-Tie Axes

(2017) Kiyoko Setoguchi et al.   Molecular Therapy-Nucleic Acids

UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis

(2016) Laurence Wurth et al.   CANCER CELL

RNA-binding protein Lin28 in cancer and immunity

(2016) Shuai Jiang et al.   CANCER LETTERS

RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts

(2016) Steffi Gieseler-Halbach et al.   CELL DEATH AND DIFFERENTIATION

p53 on the crossroad between regeneration and cancer

(2016) Meital Charni et al.   CELL DEATH AND DIFFERENTIATION

Y-box protein-1/p18 as novel serum marker for ovarian cancer diagnosis: A study by the Tumor Bank Ovarian Cancer (TOC)

(2016) Irena Rohr et al.   CYTOKINE

Hyper-O-GlcNAcylation of YB-1 affects Ser102 phosphorylation and promotes cell proliferation in hepatocellular carcinoma

(2016) Qingqing Liu et al.   EXPERIMENTAL CELL RESEARCH

ΔNp63αcontrols YB-1 protein stability: evidence on YB-1 as a new player in keratinocyte differentiation

(2016) Orsola di Martino et al.   GENES TO CELLS

Exosomes in the Pathology of Neurodegenerative Diseases

(2016) Jason Howitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ExoCarta: A Web-Based Compendium of Exosomal Cargo

(2016) Shivakumar Keerthikumar et al.   JOURNAL OF MOLECULAR BIOLOGY

Cold Shock Proteins Mediate GN with Mesangioproliferation

(2016) C. Zhu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A remedy for kidney disease successfully alters the cold shock protein response during inflammation

(2016) Sabine Brandt et al.   KIDNEY INTERNATIONAL

Therapeutic nuclear shuttling of YB-1 reduces renal damage and fibrosis

(2016) Jialin Wang et al.   KIDNEY INTERNATIONAL

Progranulin promotes peripheral nerve regeneration and reinnervation: role of notch signaling

(2016) Christine Altmann et al.   Molecular Neurodegeneration

Principles and Properties of Stress Granules

(2016) David S.W. Protter et al.   TRENDS IN CELL BIOLOGY

Hypo- and Hyper-Assembly Diseases of RNA–Protein Complexes

(2016) Siddharth Shukla et al.   TRENDS IN MOLECULAR MEDICINE

Crucial factors of the inflammatory microenvironment (IL-1β/ TNF-α/TIMP-1) promote the maintenance of the malignant hemopoietic clone of myelofibrosis: an in vitro study

(2016) Daria Sollazzo et al.   Oncotarget

Y-box protein 1 is required to sort microRNAs into exosomes in cells and in a cell-free reaction

(2016) Matthew J Shurtleff et al.   eLife

miR-155 acts as an anti-inflammatory factor in atherosclerosis-associated foam cell formation by repressing calcium-regulated heat stable protein 1

(2016) Xiaoyi Li et al.   Scientific Reports

Anti-fibrotic effects of a novel small compound on the regulation of cytokine production in a mouse model of colorectal fibrosis

(2015) Jin Imai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of the p53 response and its relationship to cancer

(2015) David W. Meek   BIOCHEMICAL JOURNAL

Post-transcriptional regulation of gene expression by Unr: Table 1

(2015) Swagat Ray et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Regulation of the expression and activity of Unr in mammalian cells

(2015) E. C. Anderson et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Stress granules, P-bodies and cancer

(2015) Paul Anderson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Hepatocytes: a key cell type for innate immunity

(2015) Zhou Zhou et al.   Cellular & Molecular Immunology

HACE1 mediated K27 ubiquitin linkage leads to YB-1 protein secretion

(2015) Vivek Reddy Palicharla et al.   CELLULAR SIGNALLING

Hepsin inhibits CDK11p58 IRES activity by suppressing unr expression and eIF-2α phosphorylation in prostate cancer

(2015) Chunyi Zhang et al.   CELLULAR SIGNALLING

Transcription factors that interact with p53 and Mdm2

(2015) Kazushi Inoue et al.   INTERNATIONAL JOURNAL OF CANCER

YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

(2015) Syam Prakash Somasekharan et al.   JOURNAL OF CELL BIOLOGY

Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 Ubiquitination

(2015) W. Dong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

TNF biology, pathogenic mechanisms and emerging therapeutic strategies

(2015) George D. Kalliolias et al.   Nature Reviews Rheumatology

mRNA and DNA selection via protein multimerization: YB-1 as a case study

(2015) Dmitry A. Kretov et al.   NUCLEIC ACIDS RESEARCH

Emerging Liver–Kidney Interactions in Nonalcoholic Fatty Liver Disease

(2015) Giovanni Musso et al.   TRENDS IN MOLECULAR MEDICINE

Critical role of phosphorylation of serine 165 of YBX1 on the activation of NF-κB in colon cancer

(2015) Lakshmi Prabhu et al.   Oncotarget

Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells

(2015) Bàrbara Castellana et al.   Oncotarget

Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression

(2015) Elizabeth Snyder et al.   PLoS Genetics

Downregulation of tumor necrosis factor and other proinflammatory biomarkers by polyphenols

(2014) Subash C. Gupta et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: Findings from 3-D melanoma skin equivalents and computational modeling

(2014) Deeba N. Syed et al.   BIOCHEMICAL PHARMACOLOGY

High prevalence of Y-box protein-1/p18 fragment in plasma of patients with malignancies of different origin

(2014) Frank Tacke et al.   BMC CANCER

p53 as a target for the treatment of cancer

(2014) Michael J. Duffy et al.   CANCER TREATMENT REVIEWS

Y-box binding protein 1 – A prognostic marker and target in tumour therapy

(2014) Corinna Kosnopfel et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Calcineurin-mediated YB-1 Dephosphorylation Regulates CCL5 Expression during Monocyte Differentiation

(2014) Christina Alidousty et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of cold shock domain proteins in inflammatory diseases

(2014) Jonathan A. Lindquist et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

PhosphoSitePlus, 2014: mutations, PTMs and recalibrations

(2014) Peter V. Hornbeck et al.   NUCLEIC ACIDS RESEARCH

Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules

(2014) Ouissame Bounedjah et al.   NUCLEIC ACIDS RESEARCH

Differential Control of Interleukin-6 mRNA Levels by Cellular Distribution of YB-1

(2014) Sujin Kang et al.   PLoS One

G-quadruplex structures contribute to the neuroprotective effects of angiogenin-induced tRNA fragments

(2014) Pavel Ivanov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of NF-κB by TNF family cytokines

(2014) Matthew S. Hayden et al.   SEMINARS IN IMMUNOLOGY

Inhibition of Akt/mTOR Signaling by the Dietary Flavonoid Fisetin

(2013) Deeba Syed et al.   Anti-Cancer Agents in Medicinal Chemistry

Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function

(2013) J. Ross Buchan et al.   CELL

Cold shock Y-box protein-1 proteolysis autoregulates its transcriptional activities

(2013) Claudia RC van Roeyen et al.   Cell Communication and Signaling

The proteolytic YB-1 fragment interacts with DNA repair machinery and enhances survival during DNA damaging stress

(2013) Ekaterina R Kim et al.   CELL CYCLE

Mechanisms of Lin28-Mediated miRNA and mRNA Regulation—A Structural and Functional Perspective

(2013) Florian Mayr et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

(2013) Marina Colombo et al.   JOURNAL OF CELL SCIENCE

YB-1 Is an Early and Central Mediator of Bacterial and Sterile Inflammation In Vivo

(2013) L. Hanssen et al.   JOURNAL OF IMMUNOLOGY

Imatinib: Novel Treatment of Immune-Mediated Kidney Injury

(2013) E. Wallace et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Transforming growth factor-  and the progression of renal disease

(2013) I. Loeffler et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Links between the Oncoprotein YB-1 and Small Non-Coding RNAs in Breast Cancer

(2013) Cherie Blenkiron et al.   PLoS One

Autism-specific maternal autoantibodies recognize critical proteins in developing brain

(2013) D Braunschweig et al.   Translational Psychiatry

Dietary flavonoid fisetin: A novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management

(2012) Vaqar Mustafa Adhami et al.   BIOCHEMICAL PHARMACOLOGY

The major mRNP protein YB-1: Structural and association properties in solution

(2012) Sergey G. Guryanov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Cell-free Formation of RNA Granules: Bound RNAs Identify Features and Components of Cellular Assemblies

(2012) Tina W. Han et al.   CELL

Rat Mrp2 gene expression is regulated by an interleukin-1β-stimulated biphasic response with enhanced transcription and subcellular shuttling of YB-1

(2012) Peter R. Mertens et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Up-regulation of dbpA mRNA in hepatocellular carcinoma associated with metabolic syndrome

(2012) Gulanbar Obulhasim et al.   Hepatology International

Lessons from mathematically modeling the NF-κB pathway

(2012) Soumen Basak et al.   IMMUNOLOGICAL REVIEWS

Y-Box Binding Protein 1 and RNase UK114 Mediate Monocyte Chemoattractant Protein 1 mRNA Stability in Vascular Smooth Muscle Cells

(2012) L. Dhawan et al.   MOLECULAR AND CELLULAR BIOLOGY

Translation suppression promotes stress granule formation and cell survival in response to cold shock

(2012) Sarah Hofmann et al.   MOLECULAR BIOLOGY OF THE CELL

Identification in the rat brain of a set of nuclear proteins interacting with H1° mRNA

(2012) C.M. Di Liegro et al.   NEUROSCIENCE

Formation of Amyloid-Like Fibrils by Y-Box Binding Protein 1 (YB-1) Is Mediated by Its Cold Shock Domain and Modulated by Disordered Terminal Domains

(2012) Sergey G. Guryanov et al.   PLoS One

Modification of RelA by O-linked N-acetylglucosamine links glucose metabolism to NF- B acetylation and transcription

(2012) D. F. Allison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy intersections with conventional and unconventional secretion in tissue development, remodeling and inflammation

(2012) Vojo Deretic et al.   TRENDS IN CELL BIOLOGY

How does Lin28 let-7 control development and disease?

(2012) James E. Thornton et al.   TRENDS IN CELL BIOLOGY

Y-box protein-1/p18 fragment identifies malignancies in patients with chronic liver disease

(2011) Frank Tacke et al.   BMC CANCER

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

Role of cold shock Y-box protein-1 in inflammation, atherosclerosis and organ transplant rejection

(2011) Ute Raffetseder et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Cold shock Y-box protein-1 participates in signaling circuits with auto-regulatory activities

(2011) Sabine Brandt et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Upregulation of mdr1 gene is related to activation of the MAPK/ERK signal transduction pathway and YB-1 nuclear translocation in B-cell lymphoma

(2011) Huiling Shen et al.   EXPERIMENTAL HEMATOLOGY

Cold-shock domain family member YB-1 expression in endometrium and endometriosis

(2011) C. G. T. Silveira et al.   HUMAN REPRODUCTION

Y-Box Binding Protein-1 Mediates Profibrotic Effects of Calcineurin Inhibitors in the Kidney

(2011) L. Hanssen et al.   JOURNAL OF IMMUNOLOGY

Extracellular YB-1 Blockade in Experimental Nephritis Upregulates Notch-3 Receptor Expression and Signaling

(2011) Ute Raffetseder et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

The RNA-Binding Protein Unr Prevents Mouse Embryonic Stem Cells Differentiation Toward the Primitive Endoderm Lineage

(2011) Habiba Elatmani et al.   STEM CELLS

YB-1 is capable of forming extended nanofibrils

(2010) O. M. Selivanova et al.   BIOCHEMISTRY-MOSCOW

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

(2010) C. Lagier-Tourenne et al.   HUMAN MOLECULAR GENETICS

Structure-Functional Analyses of CRHSP-24 Plasticity and Dynamics in Oxidative Stress Response

(2010) Hai Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Small Compound That Promotes Nuclear Translocation of YB-1 Ameliorates Experimental Hepatic Fibrosis in Mice

(2010) Kiyoshi Higashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-transcriptional Up-regulation of Tsc-22 by Ybx1, a Target of miR-216a, Mediates TGF-β-induced Collagen Expression in Kidney Cells

(2010) Mitsuo Kato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZONAB Promotes Proliferation and Represses Differentiation of Proximal Tubule Epithelial Cells

(2010) W. R. Lima et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

CARHSP1 Is Required for Effective Tumor Necrosis Factor Alpha mRNA Stabilization and Localizes to Processing Bodies and Exosomes

(2010) J. R. Pfeiffer et al.   MOLECULAR AND CELLULAR BIOLOGY

A Conserved Stem Loop Motif in the 5′Untranslated Region Regulates Transforming Growth Factor-β1 Translation

(2010) Robert H. Jenkins et al.   PLoS One

Imatinib and the Treatment of Fibrosis: Recent Trials and Tribulations

(2010) Jessica Gordon et al.   Current Rheumatology Reports

A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis

(2009) Minoru Hasegawa et al.   ARTHRITIS AND RHEUMATISM

Y-box protein-1 is actively secreted through a non-classical pathway and acts as an extracellular mitogen

(2009) Björn C Frye et al.   EMBO REPORTS

YB-1 Acts as a Ligand for Notch-3 Receptors and Modulates Receptor Activation

(2009) Thomas Rauen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein

(2008) Kirsty Sawicka et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Atomic force microscopy reveals binding of mRNA to microtubules mediated by two major mRNP proteins YB-1 and PABP

(2008) Konstantin G. Chernov et al.   FEBS LETTERS

A highly conserved molecular switch binds MSY-3 to regulate myogenin repression in postnatal muscle

(2008) L. Berghella et al.   GENES & DEVELOPMENT

IL-2 Family of Cytokines in T Regulatory Cell Development and Homeostasis

(2008) Thomas R. Malek et al.   JOURNAL OF CLINICAL IMMUNOLOGY

RBBP6 Interacts with Multifunctional Protein YB-1 through Its RING Finger Domain, Leading to Ubiquitination and Proteosomal Degradation of YB-1

(2008) Moredreck Chibi et al.   JOURNAL OF MOLECULAR BIOLOGY

Differential regulation of chemokine CCL5 expression in monocytes/macrophages and renal cells by Y-box protein-1

(2008) U.t.e. Raffetseder et al.   KIDNEY INTERNATIONAL

Regulatory Role of Human AP-Endonuclease (APE1/Ref-1) in YB-1-Mediated Activation of the Multidrug Resistance Gene MDR1

(2008) R. Chattopadhyay et al.   MOLECULAR AND CELLULAR BIOLOGY

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

The Biology of Interleukin-2

(2007) Thomas R. Malek   Annual Review of Immunology

Y-box protein-1 controls transforming growth factor-β1 translation in proximal tubular cells

(2007) D.J. Fraser et al.   KIDNEY INTERNATIONAL