13C Metabolic Flux Analysis Indicates Endothelial Cells Attenuate Metabolic Perturbations by Modulating TCA Activity

A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway

(2020) Jonathan M. Ghergurovich et al.   Nature Chemical Biology

MetaboAnalystR 3.0: Toward an Optimized Workflow for Global Metabolomics

(2020) Zhiqiang Pang et al.   Metabolites

O‐GlcNAcylation Mediates Glucose‐Induced Alterations in Endothelial Cell Phenotype in Human Diabetes Mellitus

(2020) Nobuyuki Masaki et al.   Journal of the American Heart Association

The Role of the Pentose Phosphate Pathway in Diabetes and Cancer

(2020) Tongxin Ge et al.   Frontiers in Endocrinology

Aldose reductase regulates hyperglycemia-induced HUVEC death via SIRT1/AMPK-α1/mTOR pathway

(2019) Pabitra B Pal et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Hallmarks of Endothelial Cell Metabolism in Health and Disease

(2019) Xuri Li et al.   Cell Metabolism

The MetaCyc database of metabolic pathways and enzymes - a 2019 update

(2019) Ron Caspi et al.   NUCLEIC ACIDS RESEARCH

Vascular endothelial dysfunction, a major mediator in diabetic cardiomyopathy

(2018) Maura Knapp et al.   ACTA PHARMACOLOGICA SINICA

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

(2018) Saar Vandekeere et al.   Cell Metabolism

The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids

(2018) Cholsoon Jang et al.   Cell Metabolism

Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism

(2018) Michael A. Reid et al.   Nature Communications

Malate and Aspartate Increase L-Arginine and Nitric Oxide and Attenuate Hypertension

(2017) Entai Hou et al.   Cell Reports

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium

(2017) David Wu et al.   eLife

Differential Effects of Hormones on Cellular Metabolism in Keratoconus In Vitro

(2017) Tina B. McKay et al.   Scientific Reports

The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis

(2016) Munehiro Kitada et al.   Aging-US

Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis

(2016) Laszlo Tretter et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

(2016) Anna Rita Cantelmo et al.   CANCER CELL

Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway

(2016) Concepción Peiró et al.   Cardiovascular Diabetology

Roles of O-GlcNAc in chronic diseases of aging

(2016) Partha S. Banerjee et al.   MOLECULAR ASPECTS OF MEDICINE

Sirt1 and the Mitochondria

(2016)   MOLECULES AND CELLS

2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process

(2015) Antero Salminen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Endothelial Cell Metabolism in Normal and Diseased Vasculature

(2015) Guy Eelen et al.   CIRCULATION RESEARCH

Sirtuins and the Metabolic Hurdles in Cancer

(2015) Natalie J. German et al.   CURRENT BIOLOGY

A roadmap for interpreting 13 C metabolite labeling patterns from cells

(2015) Joerg M Buescher et al.   CURRENT OPINION IN BIOTECHNOLOGY

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes

(2015) Tuomas Laukka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells

(2015) Andreas Kuehne et al.   MOLECULAR CELL

The mitochondrial carrier SLC25A10 regulates cancer cell growth

(2015) Xiaoshan Zhou et al.   Oncotarget

INCA: a computational platform for isotopically non-stationary metabolic flux analysis

(2014) J. D. Young   BIOINFORMATICS

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway

(2014) Anna Stincone et al.   BIOLOGICAL REVIEWS

The SIRT1/HIF2  Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy

(2014) C. Corbet et al.   CANCER RESEARCH

ProteinO-GlcNAcylation and Cardiovascular (Patho)physiology

(2014) Susan A. Marsh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake

(2013) Joanne C. McNelis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glucosamine Inhibits Decidualization of Human Endometrial Stromal Cells and Decreases Litter Sizes in Mice1

(2013) Jui-He Tsai et al.   BIOLOGY OF REPRODUCTION

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

DHEA-Mediated Inhibition of the Pentose Phosphate Pathway Alters Oocyte Lipid Metabolism in Mice

(2013) Patricia T. Jimenez et al.   ENDOCRINOLOGY

Nrf2 impacts cellular bioenergetics by controlling substrate availability for mitochondrial respiration

(2013) K. M. Holmstrom et al.   Biology Open

The Subcellular Compartmentalization of Arginine Metabolizing Enzymes and Their Role in Endothelial Dysfunction

(2013) Feng Chen et al.   Frontiers in Immunology

Exploratory urinary metabolic biomarkers and pathways using UPLC-Q-TOF-HDMS coupled with pattern recognition approach

(2012) Aihua Zhang et al.   ANALYST

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Targeting Aldose Reductase for the Treatment of Cancer

(2012) R. Tammali et al.   CURRENT CANCER DRUG TARGETS

Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on progression of diabetic neuropathy and other microvascular complications: multivariate epidemiological analysis based on patient background factors and severity of diabetic neurop

(2012) N. Hotta et al.   DIABETIC MEDICINE

PARP-1 Inhibition Increases Mitochondrial Metabolism through SIRT1 Activation

(2011) Péter Bai et al.   Cell Metabolism

O -GlcNAc Signaling in the Cardiovascular System

(2010) Gladys A. Ngoh et al.   CIRCULATION RESEARCH

The hexosamine biosynthesis inhibitor azaserine prevents endothelial inflammation and dysfunction under hyperglycemic condition through antioxidant effects

(2009) Angana Gupta Rajapakse et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY